Search Results - "Tao, Huizhong W"
-
1
Synaptic Specificity and Application of Anterograde Transsynaptic AAV for Probing Neural Circuitry
Published in The Journal of neuroscience (15-04-2020)“…Revealing the organization and function of neural circuits is greatly facilitated by viral tools that spread transsynaptically. Adeno-associated virus (AAV)…”
Get full text
Journal Article -
2
Sensory Cortical Control of a Visually Induced Arrest Behavior via Corticotectal Projections
Published in Neuron (Cambridge, Mass.) (06-05-2015)“…Innate defense behaviors (IDBs) evoked by threatening sensory stimuli are essential for animal survival. Although subcortical circuits are implicated in IDBs,…”
Get full text
Journal Article -
3
Distinct Inhibitory Circuits Orchestrate Cortical beta and gamma Band Oscillations
Published in Neuron (Cambridge, Mass.) (20-12-2017)“…Distinct subtypes of inhibitory interneuron are known to shape diverse rhythmic activities in the cortex, but how they interact to orchestrate specific band…”
Get full text
Journal Article -
4
Thalamocortical Innervation Pattern in Mouse Auditory and Visual Cortex: Laminar and Cell-Type Specificity
Published in Cerebral cortex (New York, N.Y. 1991) (01-06-2016)“…Despite many previous studies, the functional innervation pattern of thalamic axons and their target specificity remains to be investigated thoroughly. Here,…”
Get full text
Journal Article -
5
Scaling down of balanced excitation and inhibition by active behavioral states in auditory cortex
Published in Nature neuroscience (01-06-2014)“…The authors report that in mouse auditory cortex, the sensory-evoked spike responses of layer 2/3 (L2/3) excitatory cells were scaled down with preserved…”
Get full text
Journal Article -
6
Corticostriatal control of defense behavior in mice induced by auditory looming cues
Published in Nature communications (15-02-2021)“…Animals exhibit innate defense behaviors in response to approaching threats cued by the dynamics of sensory inputs of various modalities. The underlying neural…”
Get full text
Journal Article -
7
Contextual and cross-modality modulation of auditory cortical processing through pulvinar mediated suppression
Published in eLife (06-03-2020)“…Lateral posterior nucleus (LP) of thalamus, the rodent homologue of primate pulvinar, projects extensively to sensory cortices. However, its functional role in…”
Get full text
Journal Article -
8
Sensory- and Motor-Related Responses of Layer 1 Neurons in the Mouse Visual Cortex
Published in The Journal of neuroscience (11-12-2019)“…Cortical layer 1 (L1) contains a sparse and molecularly distinct population of inhibitory interneurons. Their location makes them ideally suited for affecting…”
Get full text
Journal Article -
9
A bottom-up reward pathway mediated by somatostatin neurons in the medial septum complex underlying appetitive learning
Published in Nature communications (07-03-2022)“…Valence detection and processing are essential for the survival of animals and their life quality in complex environments. Neural circuits underlying the…”
Get full text
Journal Article -
10
Lateral Sharpening of Cortical Frequency Tuning by Approximately Balanced Inhibition
Published in Neuron (Cambridge, Mass.) (10-04-2008)“…Cortical inhibition plays an important role in shaping neuronal processing. The underlying synaptic mechanisms remain controversial. Here, in vivo whole-cell…”
Get full text
Journal Article -
11
A feedforward inhibitory circuit mediates lateral refinement of sensory representation in upper layer 2/3 of mouse primary auditory cortex
Published in The Journal of neuroscience (08-10-2014)“…Sensory information undergoes ordered and coordinated processing across cortical layers. Whereas cortical layer (L) 4 faithfully acquires thalamic information,…”
Get full text
Journal Article -
12
Fine-tuning of pre-balanced excitation and inhibition during auditory cortical development
Published in Nature (London) (17-06-2010)“…Functional receptive fields of neurons in sensory cortices undergo progressive refinement during development. Such refinement may be attributed to the pruning…”
Get full text
Journal Article -
13
Interaural Level Difference-Dependent Gain Control and Synaptic Scaling Underlying Binaural Computation
Published in Neuron (Cambridge, Mass.) (21-08-2013)“…Binaural integration in the central nucleus of inferior colliculus (ICC) plays a critical role in sound localization. However, its arithmetic nature and…”
Get full text
Journal Article -
14
Phasic Off responses of auditory cortex underlie perception of sound duration
Published in Cell reports (Cambridge) (20-04-2021)“…It has been proposed that sound information is separately streamed into onset and offset pathways for parallel processing. However, how offset responses…”
Get full text
Journal Article -
15
Sensory processing deficits and related cortical pathological changes in Alzheimer's disease
Published in Frontiers in aging neuroscience (15-08-2023)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily affecting cognitive functions. However, sensory deficits in AD start to draw…”
Get full text
Journal Article -
16
Selective Strengthening of Intracortical Excitatory Input Leads to Receptive Field Refinement during Auditory Cortical Development
Published in The Journal of neuroscience (13-02-2019)“…In the primary auditory cortex (A1) of rats, refinement of excitatory input to layer (L)4 neurons contributes to the sharpening of their frequency selectivity…”
Get full text
Journal Article -
17
Visual Receptive Field Structure of Cortical Inhibitory Neurons Revealed by Two-Photon Imaging Guided Recording
Published in The Journal of neuroscience (26-08-2009)“…Synaptic inhibition plays an important role in shaping receptive field (RF) properties in the visual cortex. However, the underlying mechanisms remain not well…”
Get full text
Journal Article -
18
Synaptic mechanisms underlying functional dichotomy between intrinsic-bursting and regular-spiking neurons in auditory cortical layer 5
Published in The Journal of neuroscience (20-03-2013)“…Corticofugal projections from the primary auditory cortex (A1) have been shown to play a role in modulating subcortical processing. However, functional…”
Get full text
Journal Article -
19
From elementary synaptic circuits to information processing in primary auditory cortex
Published in Neuroscience and biobehavioral reviews (01-11-2011)“…A key for understanding how information is processed in the cortex is to unravel the dauntingly complex cortical neural circuitry. Recent technical…”
Get full text
Journal Article -
20
Generation of intensity selectivity by differential synaptic tuning: fast-saturating excitation but slow-saturating inhibition
Published in The Journal of neuroscience (12-12-2012)“…Intensity defines one fundamental aspect of sensory information and is specifically represented in each sensory modality. Interestingly, only in the central…”
Get full text
Journal Article