Search Results - "Tannous, Elias A"

A DNA damage–induced phosphorylation circuit enhances Mec1ATR Ddc2ATRIP recruitment to Replication Protein A by Yates, Luke A, Tannous, Elias A, Morgan, R Marc, Burgers, Peter M, Zhang, Xiaodong

“…The cell cycle checkpoint kinase Mec1ATR and its integral partner Ddc2ATRIP are vital for the DNA damage and replication stress response. Mec1–Ddc2 "senses"…”
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Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM) by Tannous, Elias A, Burgers, Peter M

“…DNA replication is a highly precise process which usually functions in a perfect rhythm with cell cycle progression. However, cells are constantly faced with…”
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A DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A by Yates, Luke A, Tannous, Elias A, Morgan, R Marc, Burgers, Peter M, Zhang, Xiaodong

“…The cell cycle checkpoint kinase Mec1 and its integral partner Ddc2 are vital for the DNA damage and replication stress response. Mec1-Ddc2…”
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Mechanism of auto-inhibition and activation of Mec1ATR checkpoint kinase by Tannous, Elias A., Yates, Luke A., Zhang, Xiaodong, Burgers, Peter M.

“…In response to DNA damage or replication fork stalling, the basal activity of Mec1 ATR is stimulated in a cell-cycle-dependent manner, leading to cell-cycle…”
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Mechanism of auto-inhibition and activation of Mec1 ATR checkpoint kinase by Tannous, Elias A, Yates, Luke A, Zhang, Xiaodong, Burgers, Peter M

“…In response to DNA damage or replication fork stalling, the basal activity of Mec1 is stimulated in a cell-cycle-dependent manner, leading to cell-cycle arrest…”
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