Search Results - "Tannous, BA"

miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells by Würdinger, Thomas, Tannous, Bakhos A., Saydam, Okay, Skog, Johan, Grau, Stephan, Soutschek, Jürgen, Weissleder, Ralph, Breakefield, Xandra O., Krichevsky, Anna M.

“…A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here, we demonstrate that a small regulatory microRNA, miR-296,…”
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Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo by Tannous, Bakhos A, Kim, Dong-Eog, Fernandez, Juliet L, Weissleder, Ralph, Breakefield, Xandra O

“…Photoproteins have played a major role in advancing our understanding of biological processes. A broader array of biocompatible, nontoxic, and novel reporters…”
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Metabolic biotinylation of cell surface receptors for in vivo imaging by Weissleder, Ralph, Tannous, Bakhos A, Grimm, Jan, Perry, Katherine F, Chen, John W, Breakefield, Xandra O

“…We have developed a versatile, potent technique for imaging cells in culture and in vivo by expressing a metabolically biotinylated cell-surface receptor and…”
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Abstract P3-12-03: Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases by Kodack, DP, Chung, E, Yamashita, H, Incio, J, Peters, A, Song, Y, Ager, E, Huang, Y, Farrar, C, Lussiez, A, Goel, S, Snuderl, M, Kamoun, W, Hiddingh, L, Tannous, BA, Fukumura, D, Engelman, JA, Jain, RK

“…Abstract Brain metastases remain a serious obstacle in the treatment of patients with human epidermal growth factor receptor-2 (HER2)-amplified breast cancer…”
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Suicidal gene therapy in an NF-κB-controlled tumor environment as monitored by a secreted blood reporter by Badr, C E, Niers, J M, Morse, D, Koelen, J A, Vandertop, P, Noske, D, Wurdinger, T, Zalloua, P A, Tannous, B A

“…The nuclear factor-κB (NF-κB) is known to be activated in many cancer types including lung, ovarian, astrocytomas, melanoma, prostate as well as glioblastoma,…”
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Combined flash- and glow-type chemiluminescent reactions for high-throughput genotyping of biallelic polymorphisms by Tannous, Bakhos A, Verhaegen, Monique, Christopoulos, Theodore K, Kourakli, Alexandra

“…The difference in light-emission kinetics between the Ca 2+-triggered bioluminescent reaction of the photoprotein aequorin (AEQ) and the alkaline phosphatase…”
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Heterobifunctional linker between antibodies and reporter genes for immunoassay development by Tannous, Bakhos A., Chiu, Norman H.L., Christopoulos, Theodore K.

“…The amplification inherent in transcription and translation of DNA has already been exploited for the development of highly sensitive immunoassays by using a…”
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T7 RNA polymerase as a self‐replicating label for antigen quantification by Tannous, Bakhos A., Laios, Eleftheria, Christopoulos, Theodore K.

“…Enzymes are used widely as labels in binding assays for protein analytes, because they provide signal amplification. Efforts at improving the assay sensitivity…”
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