Search Results - "Tanno, Tomohiro"
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Blood Pressure-Independent Effect of Olmesartan on Albuminuria in Mice Overexpressing Renin: Its Beneficial Role in the ACE2/Ang (1-7)/Mas Axis and NADPH Oxidase Expression
Published in International Heart Journal (30-11-2018)“…Enhanced renin-angiotensin activity contributes to hypertension, albuminuria, and glomerular hypertrophy. The angiotensin (Ang)-converting enzyme (ACE) 2/Ang…”
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Enhanced p122RhoGAP/DLC-1 Expression Can Be a Cause of Coronary Spasm
Published in PloS one (01-12-2015)“…We previously showed that phospholipase C (PLC)-δ1 activity was enhanced by 3-fold in patients with coronary spastic angina (CSA). We also reported that…”
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Impact of Sex Difference on Severity and Functional Outcome in Patients with Cardioembolic Stroke
Published in Journal of stroke and cerebrovascular diseases (01-11-2015)“…Introduction Female sex is a risk factor for thromboembolic events in Caucasian, but not in Japanese, patients with nonvalvular atrial fibrillation. However,…”
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NF-κB-dependent increase in tissue factor expression is responsible for hypoxic podocyte injury
Published in Clinical and experimental nephrology (01-10-2016)“…Background Fibrin deposition within glomeruli is commonly seen in kidney biopsy specimens, suggesting enhanced coagulant activity. Tissue factor (TF) is a…”
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Olmesartan Inhibits Cardiac Hypertrophy in Mice Overexpressing Renin Independently of Blood Pressure: Its Beneficial Effects on ACE2/Ang(1–7)/Mas Axis and NADPH Oxidase Expression
Published in Journal of cardiovascular pharmacology (01-06-2016)“…Enhanced renin–angiotensin activity causes hypertension and cardiac hypertrophy. The angiotensin (Ang)-converting enzyme (ACE)2/Ang(1–7)/Mas axis pathway…”
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Abstract 16460: Enhanced Trpc Channel-Mediated Ca2+ Influx in the Cells With Phospholipase C-δ1 Overexpression
Published in Circulation (New York, N.Y.) (25-11-2014)“…Abstract only Background: We recently showed that ergometrine induces coronary spasm in the mice with enhanced phospholipase C (PLC)-δ1 activity, which was…”
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Enhanced transient receptor potential channel-mediated Ca2+ influx in the cells with phospholipase C-[delta]1 overexpression: its possible role in coronary artery spasm
Published in Fundamental & clinical pharmacology (01-08-2017)“…We reported that coronary spasm was induced in the transgenic mice with the increased phospholipase C (PLC)-[delta]1 activity. We investigated the effect of…”
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Journal Article -
8
Blood Pressure-Independent Effect of Olmesartan on Albuminuria in Mice Overexpressing Renin: Its Beneficial Role in the ACE2/Ang (1-7)/Mas Axis and NADPH Oxidase Expression
Published in International Heart Journal (2018)“…Enhanced renin-angiotensin activity contributes to hypertension, albuminuria, and glomerular hypertrophy. The angiotensin (Ang)-converting enzyme (ACE) 2/Ang…”
Get full text
Journal Article -
9
Enhanced transient receptor potential channel‐mediated Ca2+ influx in the cells with phospholipase C‐δ1 overexpression: its possible role in coronary artery spasm
Published in Fundamental & clinical pharmacology (01-08-2017)“…We reported that coronary spasm was induced in the transgenic mice with the increased phospholipase C (PLC)‐δ1 activity. We investigated the effect of enhanced…”
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Journal Article -
10
Enhanced transient receptor potential channel-mediated Ca 2+ influx in the cells with phospholipase C-δ1 overexpression: its possible role in coronary artery spasm
Published in Fundamental & clinical pharmacology (01-08-2017)“…We reported that coronary spasm was induced in the transgenic mice with the increased phospholipase C (PLC)-δ1 activity. We investigated the effect of enhanced…”
Get full text
Journal Article -
11
NF-[kappa]B-dependent increase in tissue factor expression is responsible for hypoxic podocyte injury
Published in Clinical and experimental nephrology (01-10-2016)“…Background Fibrin deposition within glomeruli is commonly seen in kidney biopsy specimens, suggesting enhanced coagulant activity. Tissue factor (TF) is a…”
Get full text
Journal Article -
12
Blood Pressure-Independent Effect of Olmesartan on Albuminuria in Mice Overexpressing Renin
Published in International heart journal (28-11-2018)“…Enhanced renin-angiotensin activity contributes to hypertension, albuminuria, and glomerular hypertrophy. The angiotensin (Ang)-converting enzyme (ACE) 2/Ang…”
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