Search Results - "Taniuchi, Hideyuki"

JTP-103237, a novel monoacylglycerol acyltransferase inhibitor, modulates fat absorption and prevents diet-induced obesity by Okuma, Chihiro, Ohta, Takeshi, Tadaki, Hironobu, Hamada, Hiromi, Oda, Tomohiro, Taniuchi, Hideyuki, Yamanaka, Kenji, Ishii, Yukihito, Ohe, Yasuhiro, Yata, Shinji, Nishiu, Jun, Aratsu, Yusuke, Oshida, Shinichi, Kume, Shinichi, Kakutani, Makoto

“…Monoacylglycerol acyltransferase 2 (MGAT2) plays an important role in intestinal fat absorption. We discovered the novel MGAT2 inhibitor, JTP-103237, and…”
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JTP-103237, a monoacylglycerol acyltransferase inhibitor, prevents fatty liver and suppresses both triglyceride synthesis and de novo lipogenesis by Okuma, Chihiro, Ohta, Takeshi, Tadaki, Hironobu, Ishigure, Tatsuya, Sakata, Shohei, Taniuchi, Hideyuki, Sano, Ryuhei, Hamada, Hiromi, Kume, Shinichi, Nishiu, Jun, Kakutani, Makoto

“…Monoacyglycerol acyltransferases (MGATs) are known to play important roles in intestinal TG absorption. In contrast, the role of MGATs in the liver is still…”
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Copper-62-ATSM: A New Hypoxia Imaging Agent with High Membrane Permeability and Low Redox Potential by Fujibayashi, Yasuhisa, Taniuchi, Hideyuki, Yonekura, Yoshiharu, Ohtani, Hiroshi, Konishi, Junji, Yokoyama, Akira

“…An ideal hypoxia imaging agent should have high membrane permeability for easy access to intracellular mitochondria and low redox potential to confer stability…”
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Differential mechanism of retention of Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) (Cu-PTSM) by brain and tumor: a novel radiopharmaceutical for positron emission tomography imaging by Fujibayashi, Y, Taniuchi, H, Wada, K, Yonekura, Y, Konishi, J, Yokoyama, A

“…The reductive retention of 62Cu-PTSM was comparatively studied in the brain and Ehrlich ascites tumor cells by electron spin resonance spectrometry and…”
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Intracellular metabolism of 99mTc-d, l-HMPAO in vitro : A basic approach for understanding the hyperfixation mechanism in damaged brain by FUJIBAYASHI, Y, TANIUCHI, H, WAKI, A, YOKOYAMA, A, ISHII, Y, YONEKURA, Y

“…The mechanism of technetium-99m-labeled d,l-hexamethylpropylene amine oxime (99mTc-HMPAO) hyperfixation in damaged brain was elucidated using in vitro…”
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Development of Glycoside-Bound Radiopharmaceuticals : Novel Radioiodination Method for Digoxin by TAKEMURA, Yasutaka, FUJIBAYASHI, Yasuhisa, DOTE, Nobuhito, TANIUCHI, Hideyuki, IIJIMA, Naoko, KONISHI, Junji, YOKOYAMA, Akira

“…We combined 2-hydroxy-3-methylbenzoylhydrazide (HMBH) with glycosides as a novel method for the radioiodination of physiologically active glycosides. This…”
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Mitochondria-Selective Reduction of 62Cu-Pyruvaldehyde Bis(N4-methylthiosemicarbazone) (62Cu-PTSM) in the Murine Brain; a Novel Radiopharmaceutical for Brain Positron Emission Tomography (PET) Imaging by FUJIBAYASHI, Yasuhisa, WADA, Kouichi, TANIUCHI, Hideyuki, YONEKURA, Yoshiharu, KONISHI, Junji, YOKOYAMA, Akira

“…The retention mechanism of 62Cu-pyruvaldehyde bis(N4-methylthiosemicarbazone) (62Cu-PTSM) in the murine brain was evaluated. For this purpose, stable Cu-PTSM…”
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Hyperfixation of Copper-62-PTSM in Rat Brain After Transient Global Ischemia by Taniuchi, Hideyuki, Fujibayashi, Yasuhisa, Yonekura, Yoshiharu, Konishi, Junji, Yokoyama, Akira

“…We evaluated the regional distribution of 62Cu-pyruvaldehyde bis(N4-methylthiosemicarbazone) (62Cu-PTSM), a potential PET perfusion agent, in the rat brain and…”
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Intracellular Metabolism of 99mT c-d,l-HMPAO In Vitro: A Basic Approach for Understanding the Hyperfixation Mechanism in Damaged Brain by Fujibayashi, Yasuhisa, Taniuchi, Hideyuki, Waki, Atsuo, Yokoyama, Akira, Ishii, Yasushi, Yonekura, Yoshiharu

“…The mechanism of technetium-99m-labeled d,l-hexamethylpropylene amine oxime ( 99mTc-HMPAO) hyperfixation in damaged brain was elucidated using in vitro…”
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Cu-Pyruvaldehyde-bis (N4-methylthiosemicarbazone) (Cu-PTSM), a Metal Complex with Selective NADH-Dependent Reduction by Complex I in Brain Mitochondria : A Potential Radiopharmaceutical for Mitochondria-Functional Imaging with Positron Emission Tomography (PET) by TANIUCHI, Hideyuki, FUJIBAYASHI, Yasuhisa, OKAZAWA, Hidehiko, YONEKURA, Yoshiharu, KONISHI, Junji, YOKOYAMA, Akira

“…The reductive retention mechanism of copper (II)-pyruvaldehyde-bis (N4-methylthiosemicarbazone) (Cu-PTSM), a generator-produced positron-emitting 62Cu-labeled…”
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Cu-Pyruvaldehyde-bis (N4-methylthiosemicarbazone) (Cu-PTSM), a Metal Complex with Selective NADH-Dependent Reduction by Complex I in Brain Mitochondria by TANIUCHI, Hideyuki, FUJIBAYASHI, Yasuhisa, OKAZAWA, Hidehiko, YONEKURA, Yoshiharu, KONISHI, Junji, YOKOYAMA, Akira

“…The reductive retention mechanism of copper (II)-pyruvaldehyde-bis (N4-methylthiosemicarbazone) (Cu-PTSM), a generator-produced positron-emitting 62Cu-labeled…”
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Erratum to: Differential mechanism of retention of Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) (Cu-PTSM) by brain and tumor: A novel radiopharmaceutical for positron emission tomography imaging by Fujibayashi, Yasuhisa, Taniuchi, Hideyuki, Wada, Kouichi, Yonekura, Yoshiharu, Konishi, Junji, Yokoyama, Akira

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Development of Glycoside-Bound Radiopharmaceuticals by TAKEMURA, Yasutaka, FUJIBAYASHI, Yasuhisa, DOTE, Nobuhito, TANIUCHI, Hideyuki, IIJIMA, Naoko, KONISHI, Junji, YOKOYAMA, Akira

“…We combined 2-hydroxy-3-methylbenzoylhydrazide (HMBH) with glycosides as a novel method for the radioiodination of physiologically active glycosides. This…”
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Basic evaluation ofGa labeled digoxin derivative as a metal-labeled bifunctional radiopharmaceutical by Fujibayashi, Yasuhisa, Takemura, Yasutaka, Taniuchi, Hideyuki, Iijima, Naoko, Konishi, Junji, Yokoyama, Akira

“…To develop metal-labeled digoxin radiopharmaceuticals with affinity with anti-digoxin antibody as well as Na,K-ATPase, a digoxin derivative conjugated with…”
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Basic evaluation of67Ga labeled digoxin derivative as a metal-labeled bifunctional radiopharmaceutical by Fujibayashi, Yasuhisa, Takemura, Yasutaka, Taniuchi, Hideyuki, Iijima, Naoko, Konishi, Junji, Yokoyama, Akira

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