Search Results - "Taniai, Eriko"

Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats by Taniai, Eriko, Yafune, Atsunori, Nakajima, Masahiro, Hayashi, Shim-Mo, Nakane, Fumiyuki, Itahashi, Megu, Shibutani, Makoto

“…•Ochratoxin A induces karyomegaly in renal tubular cells without relation to induction of oxidative stress in rats.•Ochratoxin A causes cell cycle aberrations…”
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Aberrant activation of M phase proteins by cell proliferation-evoking carcinogens after 28-day administration in rats by Yafune, Atsunori, Taniai, Eriko, Morita, Reiko, Hayashi, Hitomi, Suzuki, Kazuhiko, Mitsumori, Kunitoshi, Shibutani, Makoto

“…•This study aimed to identify early prediction markers of carcinogens in rats.•Cellular distribution of cell cycle proteins was analyzed after 28-day…”
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Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action by Hayashi, Hitomi, Shimamoto, Keisuke, Taniai, Eriko, Ishii, Yuji, Morita, Reiko, Suzuki, Kazuhiko, Shibutani, Makoto, Mitsumori, Kunitoshi

“…Omeprazole (OPZ), a proton pump inhibitor, is a cytochrome P450 (CYP) 1A1/2 inducer. Some CYP1A inducers are known to have liver tumor promoting effects in…”
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Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats by Shimamoto, Keisuke, Hayashi, Hitomi, Taniai, Eriko, Morita, Reiko, Imaoka, Masako, Ishii, Yuji, Suzuki, Kazuhiko, Shibutani, Makoto, Mitsumori, Kunitoshi

“…Indole-3-carbinol (I3C) has a liver tumor promoting activity in rats, and is also known as a cytochrome p450 1A (CYP1A) inducer. The generation of reactive…”
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Pathophysiological analyses of skeletal muscle in obese type 2 diabetes SDT fatty rats by Kemmochi, Yusuke, Ohta, Takeshi, Motohashi, Yu, Kaneshige, Akihiro, Katsumi, Sohei, Kakimoto, Kochi, Yasui, Yuzo, Anagawa-Nakamura, Akiko, Toyoda, Kaoru, Taniai-Riya, Eriko, Takahashi, Akemi, Shoda, Toshiyuki, Yamada, Takahisa

“…Sarcopenia is the age-related decrease of muscle mass and function. Diabetes and obesity are known to be risk factors that exacerbate sarcopenia, but the…”
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Aberrant activation of ubiquitin D at G2 phase and apoptosis by carcinogens that evoke cell proliferation after 28-day administration in rats by Taniai, Eriko, Yafune, Atsunori, Hayashi, Hitomi, Itahashi, Megu, Hara-Kudo, Yukiko, Suzuki, Kazuhiko, Mitsumori, Kunitoshi, Shibutani, Makoto

“…We have previously reported that renal carcinogens examined in rats increase tubular cell proliferation and topoisomerase (Topo) IIα+ cells. The present study…”
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Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats by Shimamoto, Keisuke, Dewa, Yasuaki, Kemmochi, Sayaka, Taniai, Eriko, Hayashi, Hitomi, Imaoka, Masako, Shibutani, Makoto, Mitsumori, Kunitoshi

“…To investigate liver tumor-promoting potentials of indole-3-carbinol (I3C) and flutamide (FLU), changes in mRNA expression of Cyp1a and genes encoding…”
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Crosstalk between PTEN/Akt2 and TGFβ signaling involving EGF receptor down‐regulation during the tumor promotion process from the early stage in a rat two‐stage hepatocarcinogenesis model by Taniai, Eriko, Kawai, Masaomi, Dewa, Yasuaki, Nishimura, Jihei, Harada, Tomoaki, Saegusa, Yukie, Matsumoto, Sayaka, Takahashi, Miwa, Mitsumori, Kunitoshi, Shibutani, Makoto

“…The present study investigated the involvement of signaling of phosphatase and tensin homolog deleted on chromosome 10 (PTEN)/protein kinase B (Akt) and…”
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Fluctuations in cell proliferation, apoptosis, and cell cycle regulation at the early stage of tumor promotion in rat two-stage carcinogenesis models by Taniai, Eriko, Yafune, Atsunori, Kimura, Masayuki, Morita, Reiko, Nakane, Fumiyuki, Suzuki, Kazuhiko, Mitsumori, Kunitoshi, Shibutani, Makoto

“…We previously demonstrated that 28-day administration of carcinogens that evoked cell proliferation as determined by immunoreactivity for Ki-67 or…”
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Induction of ovarian toxicity in a subchronic oral toxicity study of citrinin in female BALB/c mice by Hayashi, Hitomi, Itahashi, Megu, Taniai, Eriko, Yafune, Atsunori, Sugita-Konishi, Yoshiko, Mitsumori, Kunitoshi, Shibutani, Makoto

“…The present study was performed to elucidate toxicity profile of citrinin (CTN) after repeated oral doses for 90 days, especially on the kidneys and female…”
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Disruption of Smad-dependent signaling for growth of GST-P-positive lesions from the early stage in a rat two-stage hepatocarcinogenesis model by Ichimura, Ryohei, Mizukami, Sayaka, Takahashi, Miwa, Taniai, Eriko, Kemmochi, Sayaka, Mitsumori, Kunitoshi, Shibutani, Makoto

“…To clarify the involvement of signaling of transforming growth factor (TGF)-β during the hepatocarcinogenesis, the immunohistochemical distribution of related…”
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Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model by Mizukami, Sayaka, Ichimura, Ryohei, Kemmochi, Sayaka, Wang, Liyun, Taniai, Eriko, Mitsumori, Kunitoshi, Shibutani, Makoto

“…To investigate liver tumor promotion mechanisms of copper (Cu)- and iron (Fe)-overloading, immunolocalization of metal-related biomolecules and lipid…”
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Threshold dose of liver tumor promoting effect of β-naphthoflavone in rats by Hayashi, Hitomi, Taniai, Eriko, Morita, Reiko, Yafune, Atsunori, Suzuki, Kazuhiko, Shibutani, Makoto, Mitsumori, Kunitoshi

“…To determine the threshold dose of β-Naphthoflavone (BNF) that induces hepatocellular tumor promoting effects, reactive oxygen species (ROS) generation and…”
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Hepatocellular adenoma with severe fatty change in a male Spontaneously Diabetic Torii rat by Taniai-Riya, Eriko, Miyajima, Katsuhiro, Kakimoto, Kochi, Ohta, Takeshi, Yasui, Yuzo, Kemmochi, Yusuke, Anagawa-Nakamura, Akiko, Toyoda, Kaoru, Takahashi, Akemi, Shoda, Toshiyuki

“…The Spontaneously Diabetic Torii (SDT) rat is a rat model of nonobese type 2 diabetes mellitus, and hepatocellular adenomas have not been reported in this…”
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Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone by Hayashi, Hitomi, Taniai, Eriko, Morita, Reiko, Hayashi, Masahiro, Nakamura, Daichi, Wakita, Atsushi, Suzuki, Kazuhiko, Shibutani, Makoto, Mitsumori, Kunitoshi

“…Omeprazole (OPZ) and β-naphthoflavone (BNF) are cytochrome P450 (CYP)1A inducers and have liver tumor promoting effects. In this study, we investigated the…”
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A novel JAK inhibitor JTE‐052 reduces skin inflammation and ameliorates chronic dermatitis in rodent models: Comparison with conventional therapeutic agents by Tanimoto, Atsuo, Shinozaki, Yuichi, Yamamoto, Yasuo, Katsuda, Yoshiaki, Taniai‐Riya, Eriko, Toyoda, Kaoru, Kakimoto, Kochi, Kimoto, Yukari, Amano, Wataru, Konishi, Noriko, Hayashi, Mikio

“…Janus kinases (JAKs) are required for several inflammatory cytokine signalling pathways and are implicated in the pathogenesis of chronic dermatitis, including…”
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Hepatocarcinogenic Susceptibility of Fenofibrate and Its Possible Mechanism of Carcinogenicity in a Two-Stage Hepatocarcinogenesis Model of rasH2 Mice by Kawai, Masaomi, Jin, Meilan, Nishimura, Jihei, Dewa, Yasuaki, Saegusa, Yukie, Matsumoto, Sayaka, Taniai, Eriko, Shibutani, Makoto, Mitsumori, Kunitoshi

“…Fenofibrate (FF) has previously been shown to induce hepatocellular neoplasia in a conventional mouse bioassay (NDA 1993), but there has been no report to…”
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Reversible aberration of neurogenesis targeting late-stage progenitor cells in the hippocampal dentate gyrus of rat offspring after maternal exposure to acrylamide by Ogawa, Bunichiro, Wang, Liyun, Ohishi, Takumi, Taniai, Eriko, Akane, Hirotoshi, Suzuki, Kazuhiko, Mitsumori, Kunitoshi, Shibutani, Makoto

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Protective Effect of Stachybotrys microspora Triprenyl Phenol-7 on the Deposition of IgA to the Glomerular Mesangium in Nivalenol-induced IgA Nephropathy Using BALB/c Mice by Sayaka Kemmochi, Hitomi Hayashi, Eriko Taniai, Keiji Hasumi, Yoshiko Sugita-Konishi, Susumu Kumagai, Kunitoshi Mitsumori, Makoto Shibutani

“…Abstract: Activators of tissue proteolysis including Stachybotrys microspora triprenyl phenol (SMTP)-7 are a new class of agents that are expected to be…”
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Protective Effect of Stachybotrys microspora Triprenyl Phenol-7on the Deposition of IgA to the Glomerular Mesangium in Nivalenol-induced IgA Nephropathy Using BALB/c Mice by Kemmochi, Sayaka, Hayashi, Hitomi, Taniai, Eriko, Hasumi, Keiji, Sugita-Konishi, Yoshiko, Kumagai, Susumu, Mitsumori, Kunitoshi, Shibutani, Makoto

“…Activators of tissue proteolysis including Stachybotrys microspora triprenyl phenol (SMTP)-7 are a new class of agents that are expected to be effective for…”
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