Search Results - "Tani, Eiichi"
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Involvement of Rho-Kinase–Mediated Phosphorylation of Myosin Light Chain in Enhancement of Cerebral Vasospasm
Published in Circulation research (04-08-2000)“…Subarachnoid hemorrhage (SAH) often induces a long-term narrowing of the cerebral artery called cerebral vasospasm. Myosin light chain (MLC) in the spastic…”
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Molecular mechanisms involved in development of cerebral vasospasm
Published in Neurosurgical focus (15-03-2002)“…Although the agents responsible for production of vasospasm have not yet been clearly identified, the author reviews the molecular mechanisms involved in…”
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3
Endovascular treatment of ruptured dissecting aneurysms aimed at occlusion of the dissected site by using Guglielmi detachable coils
Published in Journal of neurosurgery (01-05-1999)“…Surgical or endovascular occlusion of the parent artery proximal to an aneurysm has been recommended for treatment of dissecting aneurysms of the intracranial…”
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4
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas
Published in Journal of neurosurgery (01-08-1995)“…The gene expression of five matrix metalloproteinases (MMPs) and two tissue inhibitors of metalloproteinases (TIMPs) was studied in human gliomas in vivo and…”
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5
Activation of Stress-activated Protein Kinase/c-Jun NH2-terminal Kinase and p38 Kinase in Calphostin C-induced Apoptosis Requires Caspase-3-like Proteases but Is Dispensable for Cell Death
Published in The Journal of biological chemistry (26-02-1999)“…Apoptosis was induced in human glioma cell lines by exposure to 100 n m calphostin C, a specific inhibitor of protein kinase C. Calphostin C-induced apoptosis…”
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6
Continuous elevation of intracellular Ca2+ is essential for the development of cerebral vasospasm
Published in Current vascular pharmacology (01-01-2004)“…Subarachnoid hemorrhage (SAH)-induced cerebral vasospasm causes serious neurological morbidity and mortality mainly because of the absence of effective…”
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7
Cytotoxic fragment of amyloid precursor protein accumulates in hippocampus after global forebrain ischemia
Published in Journal of cerebral blood flow and metabolism (01-11-1996)“…We developed an antibody specific to beta-amyloid precursor protein (beta APP) fragments possessing the exact amino terminus of the beta-amyloid peptide and…”
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8
Calpain inhibitor entrapped in liposome rescues ischemic neuronal damage
Published in Brain research (20-02-1999)“…Transient forebrain ischemia induces activation of calpain and proteolysis of a neuronal cytoskeleton, fodrin, in gerbil hippocampus. This phenomenon precedes…”
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9
Activation of Protein Kinases in Canine Basilar Artery in Vasospasm
Published in Journal of cerebral blood flow and metabolism (01-01-1999)“…Subarachnoid hemorrhage (SAH) often leads to a long-term narrowing of cerebral artery called vasospasm. To understand the molecular mechanisms in vasospasm,…”
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10
Up- and down-regulation of calpain inhibitor polypeptide, calpastatin, in postischemic hippocampus
Published in Neuroscience letters (16-05-1997)“…Based on our previous observation that transient forebrain ischemia induces calpain-catalyzed proteolysis in gerbil hippocampus in a region-specific manner, we…”
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11
Generation of the catalytic fragment of protein kinase C alpha in spastic canine basilar artery
Published in Journal of neurosurgery (01-11-1997)“…In previous studies of topical application of calphostin C, a specific inhibitor of the regulatory domain of protein kinase C (PKC), and calpeptin, a selective…”
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12
Expression of P-glycoprotein in human glioma cell lines and surgical glioma specimens
Published in Journal of neurosurgery (01-03-1991)“…✓ The expression of P-glycoprotein, a product of multidrug resistance gene 1, was studied by Western blotting and immunohistochemistry in five human glioma…”
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13
Activity of smooth muscle phosphatases 1 and 2A in rabbit basilar artery in vasospasm
Published in Stroke (1970) (01-12-1995)“…Subarachnoid hemorrhage frequently leads to a long-term cerebral artery narrowing called vasospasm. Recently, the involvement of myosin light chain kinase has…”
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14
Effects of ML-9 on experimental delayed cerebral vasospasm
Published in Journal of neurosurgery (01-12-1989)“…Experimental delayed cerebral vasospasm was produced in a two-hemorrhage canine model. The spastic basilar artery was exposed via the transclival route under a…”
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15
S-A-2. Polygonal Crystalline Structures in a Human Oilgodendroglioma
Published in Neurologia medico-chirurgica (1965)Get full text
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16
Proteasome inhibitors induce Fas‐mediated apoptosis by c‐Myc accumulation and subsequent induction of FasL message in human glioma cells
Published in FEBS letters (24-08-2001)“…Proteasome inhibitors were shown previously to induce mitochondria‐independent and caspase‐3‐dependent apoptosis in human glioma cell lines by unknown…”
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17
Effect of selective inhibitor of thromboxane A2 synthetase on cerebral vasospasm after early surgery
Published in Journal of neurosurgery (01-07-1984)“…The authors report the results of inhibition of thromboxane A2 synthetase in 49 consecutive patients with subarachnoid hemorrhage (SAH). These unselected Grade…”
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18
Proteasome inhibitors induce mitochondria-independent apoptosis in human glioma cells
Published in FEBS letters (29-01-1999)“…The proteasome inhibitors lactacystin and AcLLNal induced p53-independent apoptosis in two human glioma cell lines, and the apoptosis was accompanied by…”
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19
Spatial resolution of fodrin proteolysis in postischemic brain
Published in The Journal of biological chemistry (25-11-1993)“…One of the major obstacles in investigating in vivo proteolytic phenomena has been the inaccessibility to spatial information as to where in the tissue the…”
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20
Morphological Study of Experimental Cerebral Vasospasm
Published in Neurologia medico-chirurgica (1977)“…Canine basilar artery was studied in vivo and in vitro. Cell membranes of vascular smooth muscle were differentiated into caveolae intracellulares zones and…”
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