Search Results - "Tangy, Frédéric"

Chikungunya Virus Vaccines: Viral Vector–Based Approaches by Ramsauer, Katrin, Tangy, Frédéric

“…In 2013, a major chikungunya virus (CHIKV) epidemic reached the Americas. In the past 2 years, >1.7 million people have been infected. In light of the current…”
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On Dihydroorotate Dehydrogenases and Their Inhibitors and Uses by Munier-Lehmann, Hélène, Vidalain, Pierre-Olivier, Tangy, Frédéric, Janin, Yves L

“…Proper nucleosides availability is crucial for the proliferation of living entities (eukaryotic cells, parasites, bacteria, and virus). Accordingly, the uses…”
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Measles-derived vaccines to prevent emerging viral diseases by Frantz, Phanramphoei N., Teeravechyan, Samaporn, Tangy, Frédéric

“…Infectious disease epidemics match wars and natural disasters in their capacity to threaten lives and damage economies. Like SARS previously and Zika recently,…”
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Viruses to rescue health: Vaccination by Tangy, Frédéric, Tournier, Jean-Nicolas

“…Viruses have been used as tools to prevent viral infections themselves for more than two centuries with impressive success. After the empirical discoveries of…”
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RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes by Chazal, Maxime, Beauclair, Guillaume, Gracias, Ségolène, Najburg, Valérie, Simon-Lorière, Etienne, Tangy, Frédéric, Komarova, Anastassia V., Jouvenet, Nolwenn

“…The flavivirus genus comprises major human pathogens, such as Dengue (DENV) and Zika (ZIKV) viruses. RIG-I and MDA5 are key cytoplasmic pathogen recognition…”
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A chromosome‐level assembly of the black tiger shrimp (Penaeus monodon) genome facilitates the identification of growth‐associated genes by Uengwetwanit, Tanaporn, Pootakham, Wirulda, Nookaew, Intawat, Sonthirod, Chutima, Angthong, Pacharaporn, Sittikankaew, Kanchana, Rungrassamee, Wanilada, Arayamethakorn, Sopacha, Wongsurawat, Thidathip, Jenjaroenpun, Piroon, Sangsrakru, Duangjai, Leelatanawit, Rungnapa, Khudet, Jutatip, Koehorst, Jasper J., Schaap, Peter J., Martins dos Santos, Vitor, Tangy, Frédéric, Karoonuthaisiri, Nitsara

“…To salvage marine ecosystems from fishery overexploitation, sustainable and efficient aquaculture must be emphasized. The knowledge obtained from available…”
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An ACE2-Based Bimodular Fusion Protein Enables Reorientation of Endogenous Anti–Epstein-Barr Virus Antibodies Toward SARS-CoV-2 Spike by Chêne, Arnaud, Desrames, Alexandra, Tomlinson, Alice, Ruffié, Claude, Tangy, Frédéric, Gamain, Benoît

“…Abstract The use of soluble recombinant angiotensin-converting enzyme 2 (rACE2) as a decoy capable of blocking SARS-CoV-2 entry into cells has been envisaged…”
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Species-specific impact of the autophagy machinery on Chikungunya virus infection by Judith, Delphine, Mostowy, Serge, Bourai, Mehdi, Gangneux, Nicolas, Lelek, Mickaël, Lucas-Hourani, Marianne, Cayet, Nadège, Jacob, Yves, Prévost, Marie-Christine, Pierre, Philippe, Tangy, Frédéric, Zimmer, Christophe, Vidalain, Pierre-Olivier, Couderc, Thérèse, Lecuit, Marc

“…Chikungunya virus (CHIKV) is a recently re‐emerged arbovirus that triggers autophagy. Here, we show that CHIKV interacts with components of the autophagy…”
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LGP2 binds to PACT to regulate RIG-I- and MDA5-mediated antiviral responses by Sanchez David, Raul Y, Combredet, Chantal, Najburg, Valérie, Millot, Gael A, Beauclair, Guillaume, Schwikowski, Benno, Léger, Thibaut, Camadro, Jean-Michel, Jacob, Yves, Bellalou, Jacques, Jouvenet, Nolwenn, Tangy, Frédéric, Komarova, Anastassia V

“…The retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) RIG-I, MDA5, and LGP2 stimulate inflammatory and antiviral responses by sensing nonself RNA…”
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DI-tector : defective interfering viral genomes' detector for next-generation sequencing data by Beauclair, Guillaume, Mura, Marie, Combredet, Chantal, Tangy, Frédéric, Jouvenet, Nolwenn, Komarova, Anastassia V

“…Defective interfering (DI) genomes, or defective viral genomes (DVGs), are truncated viral genomes generated during replication of most viruses, including live…”
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Comparative analysis of viral RNA signatures on different RIG-I-like receptors by Sanchez David, Raul Y, Combredet, Chantal, Sismeiro, Odile, Dillies, Marie-Agnès, Jagla, Bernd, Coppée, Jean-Yves, Mura, Marie, Guerbois Galla, Mathilde, Despres, Philippe, Tangy, Frédéric, Komarova, Anastassia V

“…The RIG-I-like receptors (RLRs) play a major role in sensing RNA virus infection to initiate and modulate antiviral immunity. They interact with particular…”
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Measles virus induces oncolysis of mesothelioma cells and allows dendritic cells to cross-prime tumor-specific CD8 response by Gauvrit, Anne, Brandler, Samantha, Sapede-Peroz, Carole, Boisgerault, Nicolas, Tangy, Frédéric, Gregoire, Marc

“…Despite conventional medical and surgical treatments, malignant pleural mesothelioma (MPM) remains incurable. Oncovirotherapy (i.e., the use of…”
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A Human Coronavirus Responsible for the Common Cold Massively Kills Dendritic Cells but Not Monocytes by MESEL-LEMOINE, Mariana, MILLET, Jean, VIDALAIN, Pierre-Olivier, LAW, Helen, VABRET, Astrid, LORIN, Valérie, ESCRIOU, Nicolas, ALBERT, Matthew L, NAL, Beatrice, TANGY, Frederic

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Discovery of Genes that Modulate Flavivirus Replication in an Interferon-Dependent Manner by Lesage, Sarah, Chazal, Maxime, Beauclair, Guillaume, Batalie, Damien, Cerboni, Silvia, Couderc, Elodie, Lescure, Aurianne, Del Nery, Elaine, Tangy, Frédéric, Martin, Annette, Manel, Nicolas, Jouvenet, Nolwenn

“…[Display omitted] •Numerous genes that contribute to the antiviral state remain to be identified.•A screen recovered host proteins that modulate ZIKV…”
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Measles Virus Vaccine―Infected Tumor Cells Induce Tumor Antigen Cross-Presentation by Human Plasmacytoid Dendritic Cells by GUILLERME, Jean-Baptiste, BOISGERAULT, Nicolas, ROULOIS, David, MENAGER, Jérémie, COMBREDET, Chantal, TANGY, Frédéric, FONTENEAU, Jean-François, GREGOIRE, Marc

“…Plasmacytoid dendritic cells (pDC) are antigen-presenting cells specialized in antiviral response. The measles virus vaccine is proposed as an antitumor agent…”
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Sustained autophagy contributes to measles virus infectivity by Richetta, Clémence, Grégoire, Isabel P, Verlhac, Pauline, Azocar, Olga, Baguet, Joël, Flacher, Monique, Tangy, Frédéric, Rabourdin-Combe, Chantal, Faure, Mathias

“…The interplay between autophagy and intracellular pathogens is intricate as autophagy is an essential cellular response to fight against infections, whereas…”
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Measles-vectored vaccine approaches against viral infections: a focus on Chikungunya by Gerke, Christiane, Frantz, Phanramphoei N, Ramsauer, Katrin, Tangy, Frédéric

“…The large global burden of viral infections and especially the rapidly spreading vector-borne diseases and other emerging viral diseases show the need for new…”
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Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity by Lucas-Hourani, Marianne, Dauzonne, Daniel, Jorda, Pierre, Cousin, Gaëlle, Lupan, Alexandru, Helynck, Olivier, Caignard, Grégory, Janvier, Geneviève, André-Leroux, Gwénaëlle, Khiar, Samira, Escriou, Nicolas, Desprès, Philippe, Jacob, Yves, Munier-Lehmann, Hélène, Tangy, Frédéric, Vidalain, Pierre-Olivier

“…Searching for stimulators of the innate antiviral response is an appealing approach to develop novel therapeutics against viral infections. Here, we…”
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NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway by Cui, Shuzhi, Xia, Tian, Zhao, Jianjin, Ren, Xiaoyu, Wu, Tingtao, Kameni, Mireille, Guo, Xiaoju, He, Li, Guo, Jingao, Duperray-Susini, Aléria, Levillayer, Florence, Collard, Jean-Marc, Zhong, Jin, Pan, Lifeng, Tangy, Frédéric, Vidalain, Pierre-Olivier, Zhou, Dongming, Jiu, Yaming, Faure, Mathias, Wei, Yu

“…Autophagy receptor NDP52 triggers bacterial autophagy against infection. However, the ability of NDP52 to protect against viral infection has not been…”
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A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters by Frantz, Phanramphoei N., Barinov, Aleksandr, Ruffié, Claude, Combredet, Chantal, Najburg, Valérie, de Melo, Guilherme Dias, Larrous, Florence, Kergoat, Lauriane, Teeravechyan, Samaporn, Jongkaewwattana, Anan, Billon-Denis, Emmanuelle, Tournier, Jean-Nicolas, Prot, Matthieu, Levillayer, Laurine, Conquet, Laurine, Montagutelli, Xavier, Tichit, Magali, Hardy, David, Fernandes, Priyanka, Strick-Marchand, Hélène, Di Santo, James, Simon-Lorière, Etienne, Bourhy, Hervé, Tangy, Frédéric

“…Several COVID-19 vaccines have now been deployed to tackle the SARS-CoV-2 pandemic, most of them based on messenger RNA or adenovirus vectors.The duration of…”
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