Search Results - "Tang, Zhaohua"
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Tanshinone IIA reduces AQP4 expression and astrocyte swelling after OGD/R by inhibiting the HMGB1/RAGE/NF-κB/IL-6 pro-inflammatory axis
Published in Scientific reports (18-08-2022)“…This study aimed to investigate the role of tanshinone IIA (TSO IIA) in astrocytic swelling caused by ischemia–reperfusion-like injury in an in vitro model and…”
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Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas
Published in Cancer cell international (03-01-2020)“…Gliomas account for the major part of primary brain tumors. Based on their histology and molecular alternations, adult gliomas have been classified into four…”
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Protective effects and regulatory pathways of melatonin in traumatic brain injury mice model: Transcriptomics and bioinformatics analysis
Published in Frontiers in molecular neuroscience (09-09-2022)“…Traumatic brain injury (TBI) is the leading cause of disability and mortality globally. Melatonin (Mel) is a neuroendocrine hormone synthesized from the pineal…”
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Protective effects of erythropoietin on astrocytic swelling after oxygen–glucose deprivation and reoxygenation: Mediation through AQP4 expression and MAPK pathway
Published in Neuropharmacology (01-04-2013)“…Recent in vivo studies have shown that erythropoietin (EPO) offers strong protection against brain edema. However, the intracellular and molecular mechanisms…”
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Comparative Genomic Screen in Two Yeasts Reveals Conserved Pathways in the Response Network to Phenol Stress
Published in G3 : genes - genomes - genetics (01-03-2019)“…Living organisms encounter various perturbations, and response mechanisms to such perturbations are vital for species survival. Defective stress responses are…”
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γ射线在文献档案纸张杀虫灭菌中的应用
Published in 辐射研究与辐射工艺学报 (2020)“…TL99; 采用γ射线对纸张(模拟纸质文献档案)样品进行辐照,考察杀虫灭菌效果.分析辐照后纸张的力学性能和图案字迹颜色等,优化辐照最佳吸收剂量.结果表明:吸收剂量为2…”
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Model Organisms for Studying the Cell Cycle
Published in Methods in molecular biology (Clifton, N.J.) (2016)“…Regulation of the cell-division cycle is fundamental for the growth, development, and reproduction of all species of life. In the past several decades, a…”
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Phosphorylation by SR kinases regulates the binding of PTB-associated splicing factor (PSF) to the pre-mRNA polypyrimidine tract
Published in FEBS letters (23-01-2007)“…PSF (PTB-associated splicing factor) is a multi-functional protein that participates in transcription and RNA processing. While phosphorylation of PSF has been…”
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Two distinct mechanisms for negative regulation of the Wee1 protein kinase
Published in The EMBO journal (01-09-1993)“…The Wee1 protein kinase negatively regulates the entry into mitosis by catalyzing the inhibitory tyrosine phosphorylation of the Cdc2 protein. To examine the…”
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Influence of γ‐irradiation dose on the mechanical and tribological properties of fluoroelastomer
Published in Polymer engineering and science (01-10-2024)“…Abstract Fluoroelastomer (FKM) undergo various degrees of degradation in a gamma‐irradiated environment, leading to changes in their mechanical and…”
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A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after traumatic brain injury
Published in Molecular psychiatry (01-11-2022)“…Traumatic brain injury (TBI) can lead to different neurological and psychiatric disorders. Circular RNAs (circRNAs) are highly expressed in the nervous system…”
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Biochemical and Genetic Conservation of Fission Yeast Dsk1 and Human SR Protein-Specific Kinase 1
Published in Molecular and Cellular Biology (01-02-2000)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Fission Yeast Mitotic Regulator Dsk1 Is an SR Protein-specific Kinase
Published in The Journal of biological chemistry (06-03-1998)“…Intricate interplay may exist between pre-mRNA splicing and the cell division cycle, and fission yeast Dsk1 appears to play a role in such a connection…”
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AKT/GSK-3β/β-catenin signaling pathway participates in erythropoietin-promoted glioma proliferation
Published in Journal of neuro-oncology (01-09-2020)“…Purpose Although erythropoietin (EPO) has been proven to significantly promote the proliferation of cancer cells, the mechanism for promoting glioma…”
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Phosphoproteomics Reveals Novel Targets and Phosphoprotein Networks in Cell Cycle Mediated by Dsk1 Kinase
Published in Journal of proteome research (03-04-2020)“…As the ortholog of human SR protein kinase 1 in fission yeast Schizosaccharomyces pombe, Dsk1 specifically phosphorylates SR proteins (serine/arginine-rich…”
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Correlation Between SNPs at the 3'UTR of the FGF2 Gene and Their Interaction with Environmental Factors in Han Chinese Diabetic Peripheral Neuropathy Patients
Published in Journal of molecular neuroscience (01-02-2021)“…FGF2 is a neurotrophic factor that can act as a key regulatory molecule of neuroprotection, neurogenesis, and angiogenesis in various injuries. To explore the…”
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Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition
Published in Neuropharmacology (01-11-2014)“…Recently, increasing evidence has shown that cell cycle activation is a key factor of neuronal death and neurological dysfunction after traumatic brain injury…”
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Apolipoprotein E protects astrocytes from hypoxia and glutamate-induced apoptosis
Published in FEBS letters (16-01-2013)“…► ApoE protects astrocytes from hypoxia-induced apoptosis in a dose-dependent manner. ► The protective effect of apoE was mimicked by MK-801. ► ApoE decreased…”
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The Crucial Role of Cyclin-Dependent Kinase-5-Ataxia-Telangiectasia Mutated Axis in ICH-Induced Neuronal Injury of Rat Model
Published in Molecular neurobiology (01-11-2016)“…Cyclin-dependent kinase 5 (CDK5) and ataxia-telangiectasia mutated (ATM) are involved in normal human neurodevelopment and serves as a switch between neuronal…”
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