Search Results - "Tang, Y T"
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Non-equilibrium conditions inside rock pores drive fission, maintenance and selection of coacervate protocells
Published in Nature chemistry (01-01-2022)“…Key requirements for the first cells on Earth include the ability to compartmentalize and evolve. Compartmentalization spatially localizes biomolecules from a…”
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2
Reversible pH‐Responsive Coacervate Formation in Lipid Vesicles Activates Dormant Enzymatic Reactions
Published in Angewandte Chemie International Edition (06-04-2020)“…In situ, reversible coacervate formation within lipid vesicles represents a key step in the development of responsive synthetic cellular models. Herein, we…”
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3
MaxSynBio: Avenues Towards Creating Cells from the Bottom Up
Published in Angewandte Chemie International Edition (08-10-2018)“…A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective…”
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4
Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning
Published in Nature chemistry (01-04-2022)“…It has long been proposed that phase-separated compartments can provide a basis for the formation of cellular precursors in prebiotic environments. However, we…”
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5
Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model
Published in Nature chemistry (01-06-2014)“…Mechanisms of prebiotic compartmentalization are central to providing insights into how protocellular systems emerged on the early Earth. Protocell models are…”
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6
In vitro gene expression within membrane-free coacervate protocells
Published in Chemical communications (Cambridge, England) (21-07-2015)“…Cell-free gene expression of a fluorescent protein (mCherry) is demonstrated within the molecularly crowded matrix of a polysaccharide/polypeptide coacervate…”
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7
Enhanced Ribozyme‐Catalyzed Recombination and Oligonucleotide Assembly in Peptide‐RNA Condensates
Published in Angewandte Chemie International Edition (06-12-2021)“…The ability of RNA to catalyze RNA ligation is critical to its central role in many prebiotic model scenarios, in particular the copying of information during…”
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8
Controlling Protein Nanocage Assembly with Hydrostatic Pressure
Published in Journal of the American Chemical Society (09-12-2020)“…Controlling the assembly and disassembly of nanoscale protein cages for the capture and internalization of protein or non-proteinaceous components is…”
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9
Microfluidic Formation of Membrane-Free Aqueous Coacervate Droplets in Water
Published in Angewandte Chemie International Edition (13-07-2015)“…We report on the formation of coacervate droplets from poly(diallyldimethylammonium chloride) with either adenosine triphosphate or carboxymethyl‐dextran using…”
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10
Microfluidic formation of proteinosomes
Published in Chemical communications (Cambridge, England) (2018)“…Herein we describe a novel microfluidic method for the generation of proteinosome micro-droplets, based on bovine serum albumin and glucose oxidase conjugated…”
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11
Frontiers in biomolecular condensate research
Published in Nature cell biology (01-04-2023)“…Biomolecular condensation of macromolecules is an increasingly important concept in cell biology. Indeed, research on condensates touches on multiple areas of…”
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12
Can coacervation unify disparate hypotheses in the origin of cellular life?
Published in Current opinion in colloid & interface science (01-04-2021)“…Here, we review the recent progress in the characterisation and utilisation of coacervates as protocell models in the origin of life studies. We provide…”
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13
Ribozyme activity modulates the physical properties of RNA-peptide coacervates
Published in eLife (16-06-2023)“…Condensed coacervate phases are now understood to be important features of modern cell biology, as well as valuable protocellular models in origin-of-life…”
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14
IMPACT OF TYPHOONS ON THE OCEAN IN THE PACIFIC
Published in Bulletin of the American Meteorological Society (01-09-2014)“…Tropical cyclones (TCs) change the ocean by mixing deeper water into the surface layers, by the direct air–sea exchange of moisture and heat from the sea…”
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15
Special Issue on Bottom‐Up Synthetic Biology
Published in Chembiochem : a European journal of chemical biology (15-10-2019)“…Bottom‐up synthetic biology uses both biological and artificial chemical building blocks to create biomimetic systems, including artificial cells. Existing and…”
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16
Gene-Mediated Chemical Communication in Synthetic Protocell Communities
Published in ACS synthetic biology (16-02-2018)“…A gene-directed chemical communication pathway between synthetic protocell signaling transmitters (lipid vesicles) and receivers (proteinosomes) was designed,…”
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17
Characterization of RNA content in individual phase-separated coacervate microdroplets
Published in Nature communications (12-05-2022)“…Condensates formed by complex coacervation are hypothesized to have played a crucial part during the origin-of-life. In living cells, condensation organizes…”
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18
Cell Free Expression in Proteinosomes Prepared from Native Protein‐PNIPAAm Conjugates
Published in Macromolecular bioscience (01-03-2024)“…Towards the goal of building synthetic cells from the bottom‐up, the establishment of micrometer‐sized compartments that contain and support cell free…”
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19
Guide Field Dependence of Energy Conversion and Magnetic Topologies in Reconnection Turbulent Outflow
Published in Geophysical research letters (16-07-2024)“…Energy conversion between the fields and the particles occurs through various physical processes within space environments. Magnetic reconnection stands out as…”
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20
Role of ultrasonography in the diagnosis of temporal arteritis
Published in British journal of surgery (01-12-2010)“…Background: Temporal artery (TA) biopsy is the current standard for diagnosing temporal arteritis, but has limited sensitivity. Colour duplex ultrasonography…”
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