Search Results - "Tang, Xiuwei"

Resveratrol: A review of preclinical studies for human cancer prevention by Athar, Mohammad, Back, Jung Ho, Tang, Xiuwei, Kim, Kwang Ho, Kopelovich, Levy, Bickers, David R., Kim, Arianna L.

“…The search for novel and effective cancer chemopreventive agents has led to the identification of various naturally occurring compounds one of which is…”
Get full text

Hedgehog signalling in skin development and cancer by Athar, Mohammad, Tang, Xiuwei, Lee, Juliette L., Kopelovich, Levy, Kim, Arianna L.

“…:  Basal cell carcinoma (BCC) is the most common human malignancy, affecting 750 000 Americans each year. The understanding of mutations that are known to…”
Get full text

Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome by Chaudhary, Sandeep C, Tang, Xiuwei, Arumugam, Aadithya, Li, Changzhao, Srivastava, Ritesh K, Weng, Zhiping, Xu, Jianmin, Zhang, Xiao, Kim, Arianna L, McKay, Kristopher, Elmets, Craig A, Kopelovich, Levy, Bickers, David R, Athar, Mohammad

“…Nevoid basal cell carcinoma syndrome (NBCCS) is a rare autosomal dominant disorder that is due, in large measure, to aberrant Shh signaling driven by mutations…”
Get full text

Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells by LIU, Su-Xian, DAVIDSON, Mercy M, XIUWEI TANG, WALKER, Winsome F, ATHAR, Mohammad, IVANOV, Vladimir, HEI, Tom K

“…Arsenic is an important environmental carcinogen that affects millions of people worldwide through contaminated water supplies. For decades, arsenic was…”
Get full text

Correction: Inhibition of p38 MAPK Signaling Augments Skin Tumorigenesis via NOX2 Driven ROS Generation by Liu, Liang, Rezvani, Hamid Reza, Back, Jung Ho, Hosseini, Mohsen, Tang, Xiuwei, Zhu, Yucui, Mahfouf, Walid, Raad, Houssam, Ragi, Grace, Athar, Mohammad, Kim, Arianna L, Bickers, David R

“…[This corrects the article DOI: 10.1371/journal.pone.0097245.]…”
Get full text

Role of p38 MAPK in UVB-Induced Inflammatory Responses in the Skin of SKH-1 Hairless Mice by Kim, Arianna L., Labasi, Jeffrey M., Zhu, Yucui, Tang, Xiuwei, McClure, Kim, Gabel, Christopher A., Athar, Mohammad, Bickers, David R.

“…The p38 mitogen-activated protein kinase (MAPK) signaling pathway is activated by numerous inflammatory mediators and environmental stresses. We assessed the…”
Get full text

Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis by ATHAR, Mohammad, CHENGXIN LI, BICKERS, David R, JINGWU XIE, XIUWEI TANG, SUMIN CHI, XIAOLI ZHANG, KIM, Arianna L, TYRING, Stephen K, KOPELOVICH, Levy, HEBERT, Jennifer, EPSTEIN, Ervin H

“…Abnormal activation of the hedgehog-signaling pathway is the pivotal abnormality driving the growth of basal cell carcinomas (BCCs), the most common type of…”
Get full text

Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling by Kim, Hyunmi, Casta, Alexandre, Tang, Xiuwei, Luke, Courtney T, Kim, Arianna L, Bickers, David R, Athar, Mohammad, Christiano, Angela M

“…In order to model squamous cell carcinoma development in vivo, researchers have long preferred hairless mouse models such as SKH-1 mice that have traditionally…”
Get full text

Cyclooxygenase-2 Expression in Murine and Human Nonmelanoma Skin Cancers: Implications for Therapeutic Approaches by An, Kathy P., Athar, Mohammad, Tang, Xiuwei, Katiyar, Santosh K., Russo, Justin, Beech, J., Aszterbaum, Michelle, Kopelovich, Levy, Epstein, Ervin H., Mukhtar, Hasan, Bickers, David R.

“…Inflammatory stimuli result in the production of cutaneous eicosanoids, which are known to contribute to the process of tumor promotion. Cyclooxygenase (COX),…”
Get full text

Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation by Liu, Liang, Rezvani, Hamid Reza, Back, Jung Ho, Hosseini, Mohsen, Tang, Xiuwei, Zhu, Yucui, Mahfouf, Walid, Raad, Houssam, Ragi, Grace, Athar, Mohammad, Kim, Arianna L, Bickers, David R

“…p38 mitogen-activated protein kinases (MAPKs) respond to a wide range of extracellular stimuli. While the inhibition of p38 signaling is implicated in the…”
Get full text

Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice by Tang, Xiuwei, Kim, Arianna L, Feith, David J, Pegg, Anthony E, Russo, Justin, Zhang, Hong, Aszterbaum, Michelle, Kopelovich, Levy, Epstein, Jr, Ervin H, Bickers, David R, Athar, Mohammad

“…Solar ultraviolet B (UVB) radiation induces cutaneous ornithine decarboxylase (ODC), the first enzyme in the polyamine-biosynthesis pathway, which drives…”
Get full text

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice by Tang, Xiuwei, Zhu, Yucui, Han, Lydia, Kim, Arianna L, Kopelovich, Levy, Bickers, David R, Athar, Mohammad

“…Mutations in the tumor suppressor p53 are detectable in over 50% of all human malignancies. Mutant p53 protein is incapable of transactivating its downstream…”
Get full text

XPC silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species by Rezvani, Hamid Reza, Rossignol, Rodrigue, Ali, Nsrein, Benard, Giovanni, Tang, Xiuwei, Yang, Hee Seung, Jouary, Thomas, de Verneuil, Hubert, Taïeb, Alain, Kim, Arianna L., Mazurier, Frédéric

“…Cancer cells utilize complex mechanisms to remodel their bioenergetic properties. We exploited the intrinsic genomic stability of xeroderma pigmentosum C (XPC)…”
Get full text

AKT1 Activation is Obligatory for Spontaneous BCC Tumor Growth in a Murine Model that Mimics Some Features of Basal Cell Nevus Syndrome by Kim, Arianna L, Back, Jung Ho, Zhu, Yucui, Tang, Xiuwei, Yardley, Nathan P, Kim, Katherine J, Athar, Mohammad, Bickers, David R

“…Patients with basal cell nevus syndrome (BCNS), also known as Gorlin syndrome, develop numerous basal cell carcinomas (BCC) due to germline mutations in the…”
Get full text

Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch +/− Mice by Xu, Jianmin, Weng, Zhiping, Arumugam, Aadithya, Tang, Xiuwei, Chaudhary, Sandeep C, Li, Changzhao, Christiano, Angela M, Elmets, Craig A, Bickers, David R, Athar, Mohammad

“…Hairless mice carrying homozygous mutations in hairless gene manifest rudimentary hair follicles (HFs), epidermal cysts, hairless phenotype, and enhanced…”
Get full text

LBP34: ANTI-HUMAN GLOBULIN (AHG) ENHANCED C1q ASSAY IMPROVES DETECTION OF DONOR SPECIFIC HLA ANTIBODIES (DSA) IN HEART TRANSPLANT RECIPIENTS WITH ANTIBODY MEDIATED REJECTION by Ge, Fengxia, Li, Lingzhi, Tang, Xiuwei, Ho, Eric, Marboe, Charles-Chuck, Vesilescu, Rodica, Liwski, Robert, Clynes, Raphael A.

“…The C1qScreen assay detects complement binding HLA antibodies. Recent studies in cardiac transplant recipients suggest that the presence of C1q positive donor…”
Get full text

Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice by Tang, Jean Y, Aszterbaum, Michelle, Athar, Mohammad, Barsanti, Franco, Cappola, Carol, Estevez, Nini, Hebert, Jennifer, Hwang, Jimmy, Khaimskiy, Yefim, Kim, Arianna, Lu, Ying, So, Po-Lin, Tang, Xiuwei, Kohn, Michael A, McCulloch, Charles E, Kopelovich, Levy, Bickers, David R, Epstein, Jr, Ervin H

“…In vitro and epidemiologic studies favor the efficacy of nonsteroidal anti-inflammatory drugs (NSAID) in preventing skin squamous photocarcinogenesis, but…”
Get full text

Donor-specific antibodies in kidney deceased donor transplantation by Ho, Eric K, Tang, Xiuwei, Lingzhi, Li, Ratner, Lloyd E, Vlad, George, Vasilescu, Rodica E

“…Aim Pre-sensitization against a broad array of HLA is associated with prolonged waiting times and inferior kidney allograft survival. Although the use of solid…”
Get full text

LBP34 by Ge, Fengxia, Li, Lingzhi, Tang, Xiuwei, Ho, Eric, Marboe, Charles-Chuck, Vesilescu, Rodica, Liwski, Robert, Clynes, Raphael A

“…Aim The C1qScreen assay detects complement binding HLA antibodies. Recent studies in cardiac transplant recipients suggest that the presence of C1q positive…”
Get full text

P015 : EVALUATION OF THE RELATIONSHIP BETWEEN PRE-TRANSPLANT EVALUATION OF DSA BY VARIOUS METHODS AND INCIDENCE OF AMR IN KIDNEY ALLOGRAFT RECIPIENTS by Ho, Eric K., Ratner, Lloyd E., Cohen, David J., Li, Lingzhi, Tang, Xiuwei, Clynes, Raphael A., Suciu-Foca, Nicole, Vlad, George, Rodica Vasilescu, E.

“…The aim of this study was to evaluate the prognostic value of the C1q-SPA assay in recipients of kidney from deceased donors. The study population consisted of…”
Get full text