Search Results - "Tang, Wanhu"

IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms by Ha, Hye-Lin, Wang, Hongshan, Pisitkun, Prapaporn, Kim, Jin-Chul, Tassi, Ilaria, Tang, Wanhu, Morasso, Maria I., Udey, Mark C., Siebenlist, Ulrich

“…Psoriasis is a chronic inflammatory skin disease characterized by abnormal keratinocyte proliferation and differentiation and by an influx of inflammatory…”
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IL-20-Receptor Signaling Delimits IL-17 Production in Psoriatic Inflammation by Ha, Hye-Lin, Wang, Hongshan, Claudio, Estefania, Tang, Wanhu, Siebenlist, Ulrich

“…IL-17 cytokines, in particular IL-17A, are critical effectors in psoriasis. Antibodies that block IL-17A are highly efficacious in treating psoriasis…”
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IL-25 Orchestrates Activation of Th Cells via Conventional Dendritic Cells in Tissue to Exacerbate Chronic House Dust Mite-Induced Asthma Pathology by Claudio, Estefania, Wang, Hongshan, Kamenyeva, Olena, Tang, Wanhu, Ha, Hye-Lin, Siebenlist, Ulrich

“…House dust mite (HDM) extract is a common trigger of asthma in humans. Chronic exposure to HDM also induces asthma-like pathology in mice. Allergic responses…”
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The NF-κB regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8+ T cells during viral infection by Jaiswal, Hemant, Ciucci, Thomas, Wang, Hongshan, Tang, Wanhu, Claudio, Estefania, Murphy, Philip M, Bosselut, Rémy, Siebenlist, Ulrich

“…Bcl-3 is an atypical member of the IκB family that acts in the nucleus to modulate transcription of many NF-κB targets in a highly context-dependent manner…”
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SeqAcademy: an educational pipeline for RNA-Seq and ChIP-Seq analysis [version 4; peer review: 2 approved, 1 not approved] by Ather, Syed Hussain, Awe, Olaitan Igbagbo, Butler, Thomas J, Denka, Tamiru, Semick, Stephen Andrew, Tang, Wanhu, Busby, Ben

“…Quantification of gene expression and characterization of gene transcript structures are central problems in molecular biology. RNA sequencing (RNA-Seq) and…”
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Functional genomics of maize submergence tolerance and cloning of the related gene Sicyp51 by Tang, Wanhu, Zhang, Zuxin, Zou, Xiling, Zheng, Yonglian

“…In this study, SSH (Suppression Subtractive Hybridization) and cDNA microarray were used to identify genes associated with waterlogging response of maize…”
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IL-17-induced NF-κB Activation via CIKS/Act1: PHYSIOLOGIC SIGNIFICANCE AND SIGNALING MECHANISMS by Sønder, Søren Ulrik, Saret, Sun, Tang, Wanhu, Sturdevant, Dan E., Porcella, Stephen F., Siebenlist, Ulrich

“…Interleukin-17 (IL-17) is essential in host defense against extracellular bacteria and fungi, especially at mucosal sites, but it also contributes…”
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IL-25 orchestrates activation of Thelper cells via conventional dendritic cells in tissue to exacerbate chronic HDM-induced asthma pathology by Claudio, Estefania, Wang, Hongshan, Kamenyeva, Olena, Tang, Wanhu, Ha, Hye-lin, Siebenlist, Ulrich

“…House dust mites (HDM) extract is a common trigger of asthma in humans. Chronic exposure to HDM also induces asthma-like pathology in mice. Allergic responses…”
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Cutting Edge: IL-25 Targets Dendritic Cells To Attract IL-9-Producing T Cells in Acute Allergic Lung Inflammation by Claudio, Estefania, Tassi, Ilaria, Wang, Hongshan, Tang, Wanhu, Ha, Hye-Lin, Siebenlist, Ulrich

“…Asthma is a common inflammatory disease of airways that is often associated with type 2 responses triggered by allergens, such as house dust mites (HDMs)…”
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Bcl‐3 inhibits lupus‐like phenotypes in BL6/lpr mice by Tang, Wanhu, Wang, Hongshan, Tian, Ruxiao, Saret, Sun, Cheon, HeeJin, Claudio, Estefania, Siebenlist, Ulrich

“…Bcl‐3 is an atypical member of the IκB family that modulates NF‐κB activity in nuclei. lpr mice carry the lpr mutation in Fas, resulting in functional loss of…”
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The Oncoprotein and Transcriptional Regulator Bcl-3 Governs Plasticity and Pathogenicity of Autoimmune T Cells by Tang, Wanhu, Wang, Hongshan, Claudio, Estefania, Tassi, Ilaria, Ha, Hye-lin, Saret, Sun, Siebenlist, Ulrich

“…Bcl-3 is an atypical member of the IκB family that modulates transcription in the nucleus via association with p50 (NF-κB1) or p52 (NF-κB2) homodimers. Despite…”
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Bcl‐3 suppresses differentiation of RORγt+ regulatory T cells by Tang, Wanhu, Saret, Sun, Tian, Ruxiao, Wang, Hongshan, Claudio, Estefania, Murphy, Philip M, Siebenlist, Ulrich

“…Regulatory T cells (Tregs) exert inhibitory function under various physiological conditions and adopt diverse characteristics following environmental cues…”
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The NF-[kappa]B regulator Bcl-3 restricts terminal differentiation and promotes memory cell formation of CD8.sup.+ T cells during viral infection by Jaiswal, Hemant, Ciucci, Thomas, Wang, Hongshan, Tang, Wanhu, Claudio, Estefania, Murphy, Philip M, Bosselut, Rémy, Siebenlist, Ulrich, Thiel, Volker, Channappanavar, Rudra

“…Bcl-3 is an atypical member of the I[kappa]B family that acts in the nucleus to modulate transcription of many NF-[kappa]B targets in a highly…”
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Functions of the ‘alarmin’ cytokine IL-25 in house dust mites-induced allergic asthma-like chronic pulmonary inflammation by Etienne, Estefania, Wang, Hongshan, Tang, Wanhu, Ha, Hye-Lin, Siebenlist, Ulrich

“…Allergic inflammatory lung disease is a complex immune response orchestrated by many cytokines, chemokines and other factors signaling danger. One of these is…”
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Abstract 1661: The pro-inflammatory role of the putative oncogene Bcl-3 by Tang, Wanhu, Wang, Hongshan, Claudio, Estefania, Siebenlist, Ulrich

“…Bcl-3 is an oncogene first identified by its translocation into the immunoglobulin alpha-locus in some cases of chronic B cell lymphocytic leukemia. Bcl-3 is…”
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IL-17 drives but can also restrain psoriatic inflammation via distinct, target cell-specific mechanisms by Siebenlist, Ulrich, Ha, Hye-lin, Wang, Hongshan, Claudio, Estefania, Tang, Wanhu

“…Psoriasis is a chronic inflammatory skin disease characterized by abnormal keratinocyte proliferation and differentiation and by an influx of inflammatory…”
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The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity by Tassi, Ilaria, Claudio, Estefania, Wang, Hongshan, Tang, Wanhu, Ha, Hye-lin, Saret, Sun, Ramaswamy, Madhu, Siegel, Richard, Siebenlist, Ulrich

“…Bcl-3 is an atypical member of the IκB family and modulates gene expression via interaction with p50/NF-κB1 or p52/NF-κB2 homodimers. We report in the present…”
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IL-25 targets dendritic cells to attract IL-9-producing T cells in acute allergic lung inflammation by Claudio, Estefania, Tassi, Ilaria, Wang, Hongshan, Tang, Wanhu, Ha, Hye-lin, Siebenlist, Ulrich

“…Asthma is a common inflammatory disease of airways, often associated with type2 responses triggered by allergens such as house dust mites (HDM). IL-25 is a key…”
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Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B by Tang, Wanhu, Wang, Weimin, Zhang, Yaxi, Liu, Shilian, Liu, Yanxin, Zheng, Dexian

“…Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in a variety of tumour cells, but not in most normal cells, and has…”
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TRAIL receptor mediates inflammatory cytokine release in an NF-[kappa]B-dependent manner by Tang, Wanhu, Wang, Weimin, Zhang, Yaxi, Liu, Shilian, Liu, Yanxin, Zheng, Dexian

“…In the present article, we report that DR4 or DR5 overexpression dramatically activates the release of the inflammatory cytokines IL-8, TNF-alpha, CCL20, MIP-2…”
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