Magnetic resonance imaging of disorders with white matter changes in children and adolescents: a pictorial essay

White matter changes are seen in a spectrum of disorders in children and adolescents. Understanding their distribution and appearance helps to reach diagnoses in daily radiologic practice. This pictorial essay will outline the magnetic resonance imaging (MRI) appearances of diseases with white matte...

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Bibliographic Details
Published in:	Pediatric radiology Vol. 53; no. 6; pp. 1188 - 1206
Main Authors:	Kwok, Po Lam, Lai, Alta Y. T., Lai, Billy M. H., Luk, Shiobhon Y., Tang, Kendrick Y. K., Wong, Wendy W. C., Khoo, Jennifer L. S.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01-05-2023 Springer Nature B.V
Subjects:	Adolescent Adolescents Autoimmune diseases Child Children Clinical aspects Cytokines Demyelinating diseases Demyelinating Diseases - diagnosis Demyelinating Diseases - pathology Demyelination Disease Disorders Encephalomyelitis Humans Imaging Leukodystrophy Leukoencephalopathies - diagnostic imaging Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical imaging Medicine Medicine & Public Health Mitochondria Multiple sclerosis Nervous system Neurocutaneous Syndromes Neuroradiology Nuclear Medicine Oncology Pediatrics Pictorial Essay Radiology Signs and symptoms Substantia alba Teenagers Ultrasound White Matter - diagnostic imaging White Matter - pathology Neurocutaneous syndromes Magnetic resonance imaging Leukodystrophy White matter disease Children Adolescents Mitochondrial disease
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Summary:	White matter changes are seen in a spectrum of disorders in children and adolescents. Understanding their distribution and appearance helps to reach diagnoses in daily radiologic practice. This pictorial essay will outline the magnetic resonance imaging (MRI) appearances of diseases with white matter changes including demyelinating diseases, dysmyelinating disorders/leukodystrophies, infections, autoimmune diseases, vascular causes, mitochondrial disorders and neurocutaneous syndromes, along with a brief overview of clinical aspects of the diseases such as typical age of presentation, etiology, symptoms and signs and treatment options. This article highlights important features in common white matter diseases in children and adolescents.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1432-1998 0301-0449 1432-1998
DOI:	10.1007/s00247-022-05580-8