Search Results - "Tang, Jonathan Cy"

A general approach for stabilizing nanobodies for intracellular expression by Dingus, John G, Tang, Jonathan C Y, Amamoto, Ryoji, Wallick, Grace K, Cepko, Constance L

“…Conventional antibodies and their derived fragments are difficult to deploy against intracellular targets in live cells, due to their bulk and structural…”
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Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies by Tang, Jonathan Cy, Drokhlyansky, Eugene, Etemad, Behzad, Rudolph, Stephanie, Guo, Binggege, Wang, Sui, Ellis, Emily G, Li, Jonathan Z, Cepko, Constance L

“…The ability to detect and/or manipulate specific cell populations based upon the presence of intracellular protein epitopes would enable many types of studies…”
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Vitamin D Supplementation for 12 Months in Older Adults Alters Regulators of Bone Metabolism but Does Not Change Wnt Signaling Pathway Markers by Christodoulou, Marilena, Aspray, Terence J, Piec, Isabelle, Washbourne, Christopher, Tang, Jonathan CY, Fraser, William D, Schoenmakers, Inez

“…ABSTRACT Vitamin D status and supplementation regulates bone metabolism and may modulate Wnt signaling. We studied the response of hormonal regulators of bone…”
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Effect of Menstrual Cycle and Hormonal Contraception on Musculoskeletal Health and Performance: Protocol for a Prospective Cohort Design and Cross-Sectional Comparison by Myers, Sarah J, Knight, Rebecca L, Wardle, Sophie L, Waldock, Kirsty Am, O'Leary, Thomas J, Jones, Richard K, Muckelt, Paul E, Eisenhauer, Anton, Tang, Jonathan Cy, Fraser, William D, Greeves, Julie P

“…Women of reproductive age experience cyclical variation in the female sex steroid hormones 17β-estradiol and progesterone during the menstrual cycle that is…”
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The Collagen Synthesis Response to an Acute Bout of Resistance Exercise Is Greater when Ingesting 30 g Hydrolyzed Collagen Compared with 15 g and 0 g in Resistance-Trained Young Men by Lee, Joonsung, Tang, Jonathan C Y, Dutton, John, Dunn, Rachel, Fraser, William D, Enright, Kevin, Clark, David R, Stewart, Claire E, Erskine, Robert M

“…Resistance exercise (RE) stimulates collagen synthesis in skeletal muscle and tendon but there is limited and equivocal evidence regarding an effect of…”
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EFFICACY OF ORAL VITAMIN D SUPPLEMENTATION OR SIMULATED SUNLIGHT ON BONE DURING MILITARY TRAINING: 1827 Board #7 May 28 1:30 PM - 3:30 PM by O'Leary, Thomas J., Izard, Rachel M., Walsh, Neil P., Tang, Jonathan CY, Fraser, William D., Greeves, Julie P.

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Vitamin D metabolites are associated with musculoskeletal injury in young adults: a prospective cohort study by Carswell, Alexander T, O'Leary, Thomas J, Swinton, Paul, Jackson, Sarah, Tang, Jonathan C Y, Oliver, Samuel J, Izard, Rachel M, Walsh, Neil P, Fraser, William D, Greeves, Julie P

“…The relationship between vitamin D metabolites and lower body (pelvis and lower limb) overuse injury is unclear. In a prospective cohort study, we investigated…”
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Causes of Musculoskeletal Pain in Paget’s Disease of Bone by Berg, Kathryn, Dockrell, Dervil, Colvin, Lesley, Fraser, William D, Tang, Jonathan CY, Aspray, Terry, Dennison, Elaine, Divyateja, Hrushikesh, Ghouri, Nazim, Hanison, Esther, Keen, Richard, McCloskey, Eugene, O’Neill, Terence W, Rahman, Faizanur, Siddiqi, Mashood, Tuck, Stephen, Turton, Jane, Ralston, Stuart H

“…Paget’s disease of bone (PDB) is characterised by increased and disorganised bone remodelling leading to various complications, such as bone deformity,…”
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Supplementary Energy Increases Bone Formation during Arduous Military Training by O’LEARY, THOMAS J., WALSH, NEIL P., CASEY, ANNA, IZARD, RACHEL M., TANG, JONATHAN C. Y., FRASER, WILLIAM D., GREEVES, JULIE P.

“…PURPOSETo investigate the effect of supplementary energy on bone formation and resorption during arduous military training in energy deficit. METHODSThirty…”
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The Relationship Between Oral Contraceptive Use With Total Hydroxyvitamin D And Its Metabolites In Young Adult Women: 2103 Board #259 May 30 3:30 PM - 5:00 PM by Greeves, Julie P., Tang, Jonathan CY, Jackson, Sarah, Walsh, Neil P., Izard, Rachel M., Fraser, William D.

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EFFECTS OF ORAL VITAMIN D OR SIMULATED SUNLIGHT ON VITAMIN D METABOLISM DURING MILITARY TRAINING: 3960 Board #277 May 30 9:00 AM - 10:30 AM by Greeves, Julie P., Izard, Rachel M., Walsh, Neil P., Tang, Jonathan CY, Fraser, William D., O’Leary, Thomas J.

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A Rare Mutation in SMAD9 Associated With High Bone Mass Identifies the SMAD‐Dependent BMP Signaling Pathway as a Potential Anabolic Target for Osteoporosis by Gregson, Celia L, Bergen, Dylan J. M., Leo, Paul, Sessions, Richard B, Wheeler, Lawrie, Hartley, April, Youlten, Scott, Croucher, Peter I, McInerney‐Leo, Aideen M, Fraser, William, Tang, Jonathan CY, Anderson, Lisa, Marshall, Mhairi, Sergot, Leon, Paternoster, Lavinia, Davey Smith, George, Brown, Matthew A, Hammond, Chrissy, Kemp, John P, Tobias, Jon H, Duncan, Emma L

“…ABSTRACT Novel anabolic drug targets are needed to treat osteoporosis. Having established a large national cohort with unexplained high bone mass (HBM), we…”
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A Nanobody-Based System Using Fluorescent Proteins as Scaffolds for Cell-Specific Gene Manipulation by Tang, Jonathan C.Y., Szikra, Tamas, Kozorovitskiy, Yevgenia, Teixiera, Miguel, Sabatini, Bernardo L., Roska, Botond, Cepko, Constance L.

“…Fluorescent proteins are commonly used to label cells across organisms, but the unmodified forms cannot control biological activities. Using GFP-binding…”
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The Effect Of Protein Supplementation On Bone Metabolism During Arduous Military Exercise In Energy Deficit: 1118 by Wardle, Sophie L., O'Leary, Thomas J., Coombs, Charlotte V., Edwards, Victoria C., Double, Rebecca L., Manderson-Koivula, Fiona N., Blacker, Sam D., Tang, Jonathan CY, Fraser, William D., Greeves, Julie P.

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Sex Differences In Bone Metabolism During An Arduous Military Field Exercise: 404 by Coombs, Charlotte V., O'Leary, Thomas J., Edwards, Victoria C., Blacker, Sam D., Double, Rebecca L., Manderson-Koivula, Fiona N., Tang, Jonathan CY, Fraser, William D., Wardle, Sophie L., Greeves, Julie P.

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The Effect Of Protein Supplementation On Bone Metabolism During Arduous Military Exercise In Energy Deficit: 1118 by Wardle, Sophie L., O'Leary, Thomas J., Coombs, Charlotte V., Edwards, Victoria C., Double, Rebecca L., Manderson-Koivula, Fiona N., Blacker, Sam D., Tang, Jonathan CY, Fraser, William D., Greeves, Julie P.

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Sex Differences In Bone Metabolism During An Arduous Military Field Exercise: 404 by Coombs, Charlotte V., O'Leary, Thomas J., Edwards, Victoria C., Blacker, Sam D., Double, Rebecca L., Manderson-Koivula, Fiona N., Tang, Jonathan CY, Fraser, William D., Wardle, Sophie L., Greeves, Julie P.

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Safety and Efficacy of Oral Human Parathyroid Hormone (1‐34) in Hypoparathyroidism: An Open‐Label Study by Ish‐Shalom, Sofia, Caraco, Yoseph, Khazen, Nariman Saba, Gershinsky, Michal, Szalat, Auryan, Schwartz, Phillip, Arbit, Ehud, Galitzer, Hillel, Tang, Jonathan CY, Burshtein, Gregory, Rothner, Ariel, Raskin, Arthur, Blum, Miriam, Fraser, William D

“…ABSTRACT The standard treatment of primary hypoparathyroidism (hypoPT) with oral calcium supplementation and calcitriol (or an analog), intended to control…”
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Female-biased dimorphism underlies a female-specific role for post-embryonic Ilp7 neurons in Drosophila fertility by Castellanos, Monica C, Tang, Jonathan C Y, Allan, Douglas W

“…In Drosophila melanogaster, much of our understanding of sexually dimorphic neuronal development and function comes from the study of male behavior, leaving…”
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Gene Regulatory Mechanisms Underlying the Spatial and Temporal Regulation of Target-Dependent Gene Expression in Drosophila Neurons: e1005754 by Berndt, Anthony JE, Tang, Jonathan CY, Ridyard, Marc S, Lian, Tianshun, Keatings, Kathleen, Allan, Douglas W

“…Neuronal differentiation often requires target-derived signals from the cells they innervate. These signals typically activate neural subtype-specific genes,…”
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