Search Results - "Tang, Jing Ping"

PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition by Wang, Haihe, Quah, Samantha Yiling, Dong, Jing Ming, Manser, Edward, Tang, Jing Ping, Zeng, Qi

“…PRL-3 is a metastasis-associated phosphatase. We and others have shown that its overexpression increases cell motility and invasiveness. These phenotypic…”
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CD103+ Dendritic Cells Control Th17 Cell Function in the Lung by Zelante, Teresa, Wong, Alicia Yoke Wei, Ping, Tang Jing, Chen, Jinmiao, Sumatoh, Hermi R., Viganò, Elena, Hong Bing, Yu, Lee, Bernett, Zolezzi, Francesca, Fric, Jan, Newell, Evan W., Mortellaro, Alessandra, Poidinger, Michael, Puccetti, Paolo, Ricciardi-Castagnoli, Paola

“…Th17 cells express diverse functional programs while retaining their Th17 identity, in some cases exhibiting a stem-cell-like phenotype. Whereas the importance…”
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Monoclonal antibodies target intracellular PRL phosphatases to inhibit cancer metastases in mice by Guo, Ke, Li, Jie, Ping Tang, Jing, Bobby Tan, Cheng Peow, Wang, Haihe, Wang, Haihe, Zeng, Qi

“…PRL-1 (phosphatase of regenerating liver-1), PRL-2, and PRL-3 are protein tyrosine phosphatases with a C-terminal prenylation motif that are localized to the…”
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Catalytic domain of PRL-3 plays an essential role in tumor metastasis: Formation of PRL-3 tumors inside the blood vessels by Guo, Ke, Li, Jie, Tang, Jing Ping, Koh, Vicki, Gan, Bin Qi, Zeng, Qi

“…PRL-3, a protein tyrosine phosphatase, has attracted much attention as its transcript is consistently upregulated in the process of colorectal cancer…”
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Generation of PRL-3- and PRL-1-Specific Monoclonal Antibodies as Potential Diagnostic Markers for Cancer Metastases by Li, Jie, Guo, Ke, Koh, Vicki Wei Chyi, Tang, Jing Ping, Gan, Bin Qi, Shi, Hong, Li, Hui Xiang, Zeng, Qi

“…Purpose: The PRL-3 mRNA is consistently elevated in metastatic samples derived from colorectal cancers. We sought to generate a specific PRL-3 monoclonal…”
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Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis by Mencarelli, Andrea, Khameneh, Hanif Javanmard, Fric, Jan, Vacca, Maurizio, El Daker, Sary, Janela, Baptiste, Tang, Jing Ping, Nabti, Sabrina, Balachander, Akhila, Lim, Tong Seng, Ginhoux, Florent, Ricciardi-Castagnoli, Paola, Mortellaro, Alessandra

“…The intestinal immune system can respond to invading pathogens yet maintain immune tolerance to self-antigens and microbiota. Myeloid cells are central to…”
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PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo by KE GUO, JIE LI, HAIHE WANG, OSATO, Motomi, JING PING TANG, QUAH, Samantha Yiling, BIN QI GAN, QI ZENG

“…We show here that PRL-3 protein is expressed in fetal heart, developing blood vessels, and pre-erythrocytes but not in their mature counterparts. These…”
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Genome-Wide Methylation Sensitive Elements Demarcate Targetable Regulatory Elements for Controllable Gene Activation by Liu, Yanjing Vera, Suryatenggara, Jeremiah, Wong, Hannan, Tang, Jing Ping, Tan, Hong Kee, Kwon, Junsu, Zhou, Qiling, Ummarino, Simone, Ebralidze, Alexander, Doench, John G., Chai, Li, Benoukraf, Touati, Hiwase, Devendra, Thomas, Daniel, Di Ruscio, Annalisa, Tenen, Daniel G., Bassal, Mahmoud Adel

“…There are multiple published studies correlating DNA methylation with gene expression, but to date, most are associative in nature without precise localization…”
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Targeting the Oncofetal Transcription Factor Protein SALL4 in Cancer By a Non-IMiD Degrader by Vu, Kim Anh L., Kumari, Kalpana, Liu, Bee Hui, Gao, Chong, Li, Feng, Tang, Jing Ping, Maddalo, Danilo, Tian, Xi, Liu, Miao, Bassal, Mahmoud Adel, Moein, Shiva, Iakovleva, Viktoriia, Tan, Justin L., Stein, Alicia J., Zhou, Qiling, Fischer, Patrick D., Sigua, Logan H., Qi, Jun, Arthanari, Haribabu, Tenen, Daniel G., Chai, Li

“…Sal-like protein 4 (SALL4) is a C2H2 zinc finger transcription factor (TF) with two naturally occurring isoforms; SALL4A and SALL4B. It is typically detected…”
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Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide by Liu, Bee Hui, Jobichen, Chacko, Chia, C. S. Brian, Chan, Tim Hon Man, Tang, Jing Ping, Chung, Theodora X. Y., Li, Jia, Poulsen, Anders, Hung, Alvin W., Koh-Stenta, Xiaoying, Tan, Yaw Sing, Verma, Chandra S., Tan, Hong Kee, Wu, Chan-Shuo, Li, Feng, Hill, Jeffrey, Joy, Joma, Yang, Henry, Chai, Li, Sivaraman, J., Tenen, Daniel G.

“…Sal-like 4 (SALL4) is a nuclear factor central to the maintenance of stem cell pluripotency and is a key component in hepatocellular carcinoma, a malignancy…”
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Targeting intracellular oncoproteins with antibody therapy or vaccination by Guo, Ke, Li, Jie, Tang, Jing Ping, Tan, Cheng Peow Bobby, Hong, Cheng William, Al-Aidaroos, Abdul Qader O, Varghese, Leyon, Huang, Caixia, Zeng, Qi

“…Antibody-based therapies have better specificity and thus improved efficacy over standard chemotherapy regimens, which result in extended survival and improved…”
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Comparison of endoscopic ultrasound, computed tomography and magnetic resonance imaging in assessment of detailed structures of pancreatic cystic neoplasms by Du, Chen, Chai, Ning-Li, Linghu, En-Qiang, Li, Hui-Kai, Sun, Li-Hua, Jiang, Lei, Wang, Xiang-Dong, Tang, Ping, Yang, Jing

“…AIM To evaluate the advantages of endoscopic ultrasound(EUS) in the assessment of detailed structures of pancreatic cystic neoplasms(PCNs) compared to computed…”
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Incidents and adverse events of endoscopic ultrasoundguided fine-needle aspiration for pancreatic cystic lesions by Chen Du Ning-Li Chai En-Qiang Linghu Hui-Kai Li Yu-Fa Sun Wei Xu Xiang-Dong Wang Ping Tang Jing Yang

“…AIM To evaluate the diagnostic value and safety mainly regarding incidents of endoscopic ultrasound-guided fine-needle aspiration(EUS-FNA) for pancreatic…”
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Engineering the first chimeric antibody in targeting intracellular PRL-3 oncoprotein for cancer therapy in mice by Guo, Ke, Tang, Jing Ping, Jie, Li, Al-Aidaroos, Abdul Qader O, Hong, Cheng William, Tan, Cheng Peow Bobby, Park, Jung Eun, Varghese, Leyon, Feng, Zhiwei, Zhou, Jianbiao, Chng, Wee Joo, Zeng, Qi

“…Antibodies are considered as 'magic bullets' because of their high specificity. It is believed that antibodies are too large to routinely enter the cytosol,…”
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Influence of Fe/P Mole Ratio on Structure and Chemical Durability of Iron-Phosphate GlassCeramics With ZrO2 by QIAN Min, XUE Tian-feng, FAN Si-jun, TANG Jing-ping, CHEN Shu-bin, HU Li-li

“…In order to study the changes of the structure and chemical durability with Fe/P mole ratio(r(Fe/P)), a series of P2O5-Fe2O3-Al2O3-Na2O-ZrO2 glass-ceramic…”
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铁磷摩尔比对含锆铁磷酸盐玻璃陶瓷结构和化学稳定性的影响 by 钱敏, 薛天锋, 凡思军, 唐景平, 陈树彬, 胡丽丽

“…TL941.11; 以P2 O5-Fe2 O3-Al2 O3-Na2…”
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Calcineurin-mediated IL-2 production by CD11c high MHCII + myeloid cells is crucial for intestinal immune homeostasis by Mencarelli, Andrea, Khameneh, Hanif Javanmard, Fric, Jan, Vacca, Maurizio, El Daker, Sary, Janela, Baptiste, Tang, Jing Ping, Nabti, Sabrina, Balachander, Akhila, Lim, Tong Seng, Ginhoux, Florent, Ricciardi-Castagnoli, Paola, Mortellaro, Alessandra

“…The intestinal immune system can respond to invading pathogens yet maintain immune tolerance to self-antigens and microbiota. Myeloid cells are central to…”
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VHZ is a novel centrosomal phosphatase associated with cell growth and human primary cancers by Tang, Jing Ping, Tan, Cheng Peow, Li, Jie, Siddique, Md Monowarul, Guo, Ke, Chan, Siew Wee, Park, Jung Eun, Tay, Wan Ngee, Huang, Zhi Yuan, Li, Wen Cai, Chen, Jian, Zeng, Qi

“…VHZ is a VH1-like (member Z) dual specific protein phosphatase encoded by DUSP23 gene. Some of the dual specific protein phosphatases (DSPs) play an important…”
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PRL-3 down-regulates PTEN expression and Signals through P13K to promote epithelial-mesenchymal transition by HAIHE WANG, SAMANTHA YILING QUAH, JING MING DONG, MANSER, Edward, JING PING TANG, QI ZENG

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Synthesis of 1,2,4-Triazine Compounds via Two Distinct One-Pot Domino Protocols by Liu, Yafeng, Guo, Xin, Tang, Dong, Wang, Jing, Wu, Ping, Han, Jianwei, Chen, Baohua

“…1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as…”
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