Search Results - "Tang, Jianbin"
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The Blood Clearance Kinetics and Pathway of Polymeric Micelles in Cancer Drug Delivery
Published in ACS nano (26-06-2018)“…Polymer micelles are one of the most investigated nanocarriers for drug delivery; many have entered clinical trials and some are in clinic use, but their…”
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The tumor EPR effect for cancer drug delivery: Current status, limitations, and alternatives
Published in Advanced drug delivery reviews (01-12-2022)“…[Display omitted] Over the past three decades, the enhanced permeability and retention (EPR) effect has been considered the basis of tumor-targeted drug…”
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A Tumor‐Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers
Published in Advanced materials (Weinheim) (01-10-2017)“…A cascade amplification release nanoparticle (CARN) is constructed by the coencapsulation of β‐lapachone and a reactive‐oxygen‐species (ROS)‐responsive…”
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The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment
Published in ACS nano (28-07-2015)“…The specific sizes that determine optimal nanoparticle tumor accumulation, penetration, and treatment remain inconclusive because many studies compared…”
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In Vivo and in Situ Tracking Cancer Chemotherapy by Highly Photostable NIR Fluorescent Theranostic Prodrug
Published in Journal of the American Chemical Society (05-03-2014)“…In vivo monitoring of the biodistribution and activation of prodrugs is urgently required. Near infrared (NIR) fluorescence-active fluorophores with excellent…”
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Transcytosis-enabled active extravasation of tumor nanomedicine
Published in Advanced drug delivery reviews (01-10-2022)“…Nanomedicines can extravasate from tumor vascular lumen into solid tumors via the EPR effect (a) or transcytosis (b). Transcytosis can be further…”
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Macromolecular MRI contrast agents: Structures, properties and applications
Published in Progress in polymer science (01-03-2013)“…Stable gadolinium chelates are widely used as the contrast agents (CAs) for magnetic resonance imaging (MRI). Conjugation of the chelates onto macromolecular…”
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Co-delivery of IOX1 and doxorubicin for antibody-independent cancer chemo-immunotherapy
Published in Nature communications (23-04-2021)“…Anti-programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) antibodies are currently used in the clinic to interupt the PD-1/PD-L1 immune…”
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9
Poly(ionic liquid)s as Optically Transparent Microwave-Absorbing Materials
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10
Intracellularly Disintegratable Polysulfoniums for Efficient Gene Delivery
Published in Advanced functional materials (25-04-2017)“…Amine‐based cationic polymers have been extensively explored as nonviral carriers for gene delivery, but inefficient intracellular unpacking of polymer/DNA…”
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Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Targeted Drug Delivery
Published in Journal of the American Chemical Society (16-01-2013)“…Cell-penetrating peptides (CPPs) such as transactivator of transcription (TAT) peptide have long been explored for promoting in vitro cell penetration and…”
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Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery
Published in Journal of the American Chemical Society (31-03-2010)“…Anticancer drugs embedded in or conjugated with inert nanocarriers, referred to as nanomedicines, show many therapeutic advantages over free drugs, but the…”
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13
The wonders of X-PDT: an advance route to cancer theranostics
Published in Journal of nanobiotechnology (25-10-2024)“…Global mortality data indicates cancer as the second-leading cause of death worldwide. Therefore, there's a pressing need to innovate effective treatments to…”
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14
Isothermal Carbon Dioxide Sorption in Poly(ionic liquid)s
Published in Industrial & engineering chemistry research (21-10-2009)“…The low-pressure isothermal sorption of CO2 in poly(ionic liquid)s (PILs) with varied structures including different cations, anions, backbones, and…”
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Strain localization of Mohr-Coulomb soils with non-associated plasticity based on micropolar continuum theory
Published in Journal of Rock Mechanics and Geotechnical Engineering (01-12-2023)“…To address the problems of strain localization, the exact Mohr-Coulomb (MC) model is used based on second-order cone programming (mpcFEM-SOCP) in the framework…”
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Zinc phthalocyanine encapsulated in polymer micelles as a potent photosensitizer for the photodynamic therapy of osteosarcoma
Published in Nanomedicine (01-06-2018)“…Zinc phthalocyanine (ZnPc) is a highly potent second-generation photosensitizer for cancer photodynamic therapy (PDT) with attractive photo-physical and…”
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Terminating the criminal collaboration in pancreatic cancer: Nanoparticle-based synergistic therapy for overcoming fibroblast-induced drug resistance
Published in Biomaterials (01-11-2017)“…Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a dismal overall prognosis mainly unchanged over the past decades. PDAC is generally refractory…”
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Multipotent Poly(Tertiary Amine‐Oxide) Micelles for Efficient Cancer Drug Delivery
Published in Advanced science (01-04-2022)“…The cancer drug delivery process involves a series of biological barriers, which require the nanomedicine to exhibit different, even opposite properties for…”
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[2]Pseudorotaxane‐Based Supramolecular Optical Indicator for the Visual Detection of Cellular Cyanide Excretion
Published in Chemistry : a European journal (13-11-2019)“…Cyanide is extremely hazardous to living organisms and the environment. Owing to its wide range of applications and high toxicity, the development of…”
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A plug-and-play monofunctional platform for targeted degradation of extracellular proteins and vesicles
Published in Nature communications (22-08-2024)“…Existing strategies use bifunctional chimaeras to mediate extracellular protein degradation. However, these strategies rely on specific lysosome-trafficking…”
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