Search Results - "Tang, Huixian"
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Utilizing AAV-mediated LEAPER 2.0 for programmable RNA editing in non-human primates and nonsense mutation correction in humanized Hurler syndrome mice
Published in Genome Biology (23-10-2023)“…Abstract Background The endogenous adenosine deaminases acting on RNA (ADAR) have been harnessed to facilitate precise adenosine-to-inosine editing on RNAs…”
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Programmable DNA pyrimidine base editing via engineered uracil-DNA glycosylase
Published in Nature communications (30-07-2024)“…DNA base editing technologies predominantly utilize engineered deaminases, limiting their ability to edit thymine and guanine directly. In this study, we…”
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Different Functional Roles of T1R Subunits in the Heteromeric Taste Receptors
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2004)“…The T1R receptors, a family of taste-specific class C G protein-coupled receptors, mediate mammalian sweet and umami tastes. The structure-function…”
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A Dynamic Mass Redistribution Assay for the Human Sweet Taste Receptor Uncovers G-Protein Dependent Biased Ligands
Published in Frontiers in pharmacology (17-02-2022)“…The sweet taste receptor is rather unique, recognizing a diverse repertoire of natural or synthetic ligands, with a surprisingly large structural diversity,…”
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Specific Alleles of Bitter Receptor Genes Influence Human Sensitivity to the Bitterness of Aloin and Saccharin
Published in Current biology (21-08-2007)“…Variation in human taste is a well-known phenomenon [1]. However, little is known about the molecular basis for it. Bitter taste in humans is believed to be…”
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Identification of Ligands for Two Human Bitter T2R Receptors
Published in Chemical senses (01-09-2004)“…Earlier, a family of G protein-coupled receptors, termed T2Rs, was identified in the rodent and human genomes through data mining. It was suggested that these…”
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Engineered circular ADAR-recruiting RNAs increase the efficiency and fidelity of RNA editing in vitro and in vivo
Published in Nature biotechnology (01-06-2022)“…Current methods for programmed RNA editing using endogenous ADAR enzymes and engineered ADAR-recruiting RNAs (arRNAs) suffer from low efficiency and bystander…”
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Circular RNA vaccines against SARS-CoV-2 and emerging variants
Published in Cell (12-05-2022)“…As the emerging variants of SARS-CoV-2 continue to drive the worldwide pandemic, there is a constant demand for vaccines that offer more effective and…”
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Sexually Transmitted Infection Screening in College Students
Published 01-01-2024“…Sexually transmitted infections (STI) are dramatically rising in young adults. Safe sex practices and education are essential for sexually transmitted…”
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Dissertation -
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Braking behaviours of C/C–SiC mated with iron/copper-based PM in dry, wet and salt fog conditions
Published in Ceramics international (01-02-2022)“…C/C–SiC composites have enormous potential as a new generation of brake materials. It is worth studying the friction and wear behaviours of these materials in…”
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Effect of soften annealing on the machinability and bonding stability of ZTA ceramic particles reinforced HCCI composite
Published in Materials letters (15-09-2022)“…•ZTA/HCCI composite was prepared by casting and the annealing process was studied.•The composite annealing at 780℃, the hardness of the components got the…”
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Microstructure and grain growth mechanism of corundum abrasive with La2O3–TiO2–SiO2 composite additives
Published in Vacuum (01-07-2022)“…Equiaxed crystal corundum abrasives were fabricated via sol-gel method with La2O3–TiO2–SiO2 composite additives and ZrO2 co-doping by using pseudo-boehmite as…”
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13
Brain potentials associated with the outcome processing in framing effects
Published in Neuroscience letters (24-10-2012)“…► We examine the neural basis of framing effects by using ERPs. ► Different FRN activities are elicited by the same but differently framed outcome. ► The FRN…”
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14
Evidence that plant K+ channel proteins have two different types of subunits
Published in Plant physiology (Bethesda) (01-09-1995)“…Plant K+ channel proteins have been previously characterized as tetramers of membrane-spanning alpha subunit polypeptides. Recent studies have identified a…”
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Ontologies in financial services: Design and applications
Published in 2011 International Conference on Business Management and Electronic Information (01-05-2011)“…Customization of financial products is the inevitable trend of financial industry and financial innovation strategy is the only way to go. Based on the…”
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Conference Proceeding -
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In vivo expression pattern of a plant K + channel β subunit protein
Published in Plant science (Limerick) (05-06-1998)“…Studies described in this report employed an antibody generated against a plant ( Arabidopsis thaliana) K + channel β subunit polypeptide (`KAB1'). Immunoblot…”
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Determination of trace Pb(II), Cd(II) and Zn(II) using differential pulse stripping voltammetry without Hg modification
Published in 中国科学:化学英文版 (2013)“…In this work, we reported a simultaneous determination approach for Pb(II), Cd(II) and Zn(II) at μg L^-1 concentration levels using differential pulse…”
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Molecular cloning and functional characterization of plant potassium channel beta subunit from Arabidopsis thaliana
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Dissertation -
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Notice of Retraction: The study of the influence mechanism of entrepreneurial social capital based on the theory of structural holes
Published in Proceedings of 2011 International Conference on Electronic & Mechanical Engineering and Information Technology (01-08-2011)Get full text
Conference Proceeding -
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Physical association of KAB1 with plant K+ channel alpha subunits
Published in The Plant cell (01-09-1996)“…K+ channel proteins contain four alpha subunits that align along a central axis perpendicular to membranes and form an ion-conducting pore. Recent work with K+…”
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