Search Results - "Tang, Chunchao"
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Theoretical Studies on Selectivity of HPK1/JAK1 Inhibitors by Molecular Dynamics Simulations and Free Energy Calculations
Published in International journal of molecular sciences (31-01-2023)“…Hematopoietic progenitor kinase 1 (HPK1) is a negative regulator of T cell receptor, which has been regarded as a potential target for immunotherapy. Yu et al…”
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cybLuc: An Effective Aminoluciferin Derivative for Deep Bioluminescence Imaging
Published in Analytical chemistry (Washington) (02-05-2017)“…To enhance the efficiency of firefly luciferase/luciferin bioluminescence imaging, a series of N-cycloalkylaminoluciferins (cyaLucs) were developed by…”
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Bioluminescent probe for detecting endogenous hypochlorite in living mice
Published in Organic & biomolecular chemistry (2018)“…As a kind of biologically important reactive oxygen species (ROS), hypochlorite (ClO ) plays a crucial role in many physiological processes. As such,…”
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Bioluminescent Probe for Detection of Starvation-Induced Pantetheinase Upregulation
Published in Analytical chemistry (Washington) (07-08-2018)“…Pantetheinase, a glycosylphosphatidylinositol (GPI) anchored enzyme, overexpresses in intestine, liver, and kidney with various biological functions such as…”
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Multiple rapid-responsive probes for hypochlorite detection based on dioxetane luminophore derivatives
Published in Journal of pharmaceutical analysis (01-06-2022)“…In recent years, various methods for detecting exogenous and endogenous hypochlorite have been studied, considering its essential role as a biomolecule…”
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Novel caged luciferin derivatives can prolong bioluminescence imaging in vitro and in vivo
Published in RSC advances (01-01-2018)“…Based on -cyclobutylaminoluciferin (cybLuc), a set of high and efficient caged bioluminescent derivatives (Clucs) as firefly luciferase pro-substrates has been…”
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Aminoluciferin 4-hydroxyphenyl amide enables bioluminescence detection of endogenous tyrosinase
Published in Organic & biomolecular chemistry (05-12-2018)“…Tyrosinase, a copper-containing enzyme existing widely in plants, animals and microorganisms, usually serves as an important biomarker in melanoma, and is also…”
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Novel caged luciferin derivatives can prolong bioluminescence imaging in vitro and in vivoElectronic supplementary information (ESI) available: Chemical synthesis and cytotoxicity test, bioluminescence imaging in vitro and in vivo, 1H NMR, 13C NMR and ESI-HRMS. See DOI: 10.1039/c8ra02312c
Published 30-05-2018“…Based on N -cyclobutylaminoluciferin (cybLuc), a set of high and efficient caged bioluminescent derivatives (Clucs) as firefly luciferase pro-substrates has…”
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