Search Results - "Tang, Chengke"

Changes in network activity with the progression of Parkinson's disease by Huang, Chaorui, Tang, Chengke, Feigin, Andrew, Lesser, Martin, Ma, Yilong, Pourfar, Michael, Dhawan, Vijay, Eidelberg, David

“…Parkinson's disease (PD) is associated with abnormal activity in spatially distributed neural systems mediating the motor and cognitive manifestations of this…”
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Abnormal metabolic network activity in Parkinson's disease: test-retest reproducibility by Ma, Yilong, Tang, Chengke, Spetsieris, Phoebe G, Dhawan, Vijay, Eidelberg, David

“…Parkinson's disease (PD) is associated with an abnormal pattern of regional brain function. The expression of this PD-related covariance pattern (PDRP) has…”
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Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial by Kaplitt, Michael G, MDPhD, Feigin, Andrew, MD, Tang, Chengke, MD, Fitzsimons, Helen L, PhD, Mattis, Paul, PhD, Lawlor, Patricia A, PhD, Bland, Ross J, PhD, Young, Deborah, PhD, Strybing, Kristin, MSc, Eidelberg, David, MD, During, Matthew J, MDDSc

“…Summary Background Dopaminergic neuronal loss in Parkinson's disease leads to changes in the circuitry of the basal ganglia, such as decreased inhibitory…”
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Assessment of the progression of Parkinson's disease: a metabolic network approach by Eckert, Thomas, MD, Tang, Chengke, MD, Eidelberg, David, MD

“…Summary Background Clinical research into Parkinson's disease has focused increasingly on the development of interventions that slow the neurodegeneration…”
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Abnormal metabolic networks in atypical parkinsonism by Eckert, Thomas, Tang, Chengke, Ma, Yilong, Brown, Nathaniel, Lin, Tanya, Frucht, Steven, Feigin, Andrew, Eidelberg, David

“…Spatial covariance analysis has been used with 18F‐fluorodeoxyglucose (FDG) PET to detect and quantify specific metabolic patterns associated with Parkinson's…”
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Dissociation of Metabolic and Neurovascular Responses to Levodopa in the Treatment of Parkinson's Disease by Hirano, Shigeki, Asanuma, Kotaro, Ma, Yilong, Tang, Chengke, Feigin, Andrew, Dhawan, Vijay, Carbon, Maren, Eidelberg, David

“…We compared the metabolic and neurovascular effects of levodopa (LD) therapy for Parkinson's disease (PD). Eleven PD patients were scanned with both [15O]-H2O…”
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Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease by Feigin, Andrew, Kaplitt, Michael G, Tang, Chengke, Lin, Tanya, Mattis, Paul, Dhawan, Vijay, During, Matthew J, Eidelberg, David

“…Parkinson's disease (PD) is characterized by elevated expression of an abnormal metabolic brain network that is reduced by clinically effective treatment. We…”
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Microstructural white matter changes in primary torsion dystonia by Carbon, Maren, Kingsley, Peter B., Tang, Chengke, Bressman, Susan, Eidelberg, David

“…Primary torsion dystonia (PTD) has been conceptualized as a disorder of the basal ganglia. However, recent data suggest a widespread pathology involving motor…”
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Metabolic correlates of subthalamic nucleus activity in Parkinson's disease by Lin, Tanya P., Carbon, Maren, Tang, Chengke, Mogilner, Alon Y., Sterio, Djordje, Beric, Aleksandar, Dhawan, Vijay, Eidelberg, David

“…Overactivity of subthalamic nucleus (STN) neurons is a consistent feature of Parkinson's disease (PD) and is a target of therapy for this disorder. However,…”
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Changes in activity of the striatum during formation of a motor habit by Tang, Chengke, Pawlak, Anthony P., Prokopenko, Volodymyr, West, Mark O.

“…To examine experience‐dependent plasticity of striatal neurons during habit learning in awake, freely moving animals, single neurons in the dorsolateral…”
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Imaging essential tremor by Isaias, Ioannis U., Marotta, Giorgio, Hirano, Shigeki, Canesi, Margherita, Benti, Riccardo, Righini, Andrea, Tang, Chengke, Cilia, Roberto, Pezzoli, Gianni, Eidelberg, David, Antonini, Angelo

“…To investigate over time changes in striatal dopamine transporter (DAT), we performed two sequential N‐ω‐fluoropropyl‐2β‐carbomethoxy‐3β‐(4‐iodophenyl) tropane…”
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Assessing the microlesion effect of subthalamic deep brain stimulation surgery with FDG PET: Clinical article by POURFAR, Michael, CHENGKE TANG, TANYA LIN, DHAWAN, Vijay, KAPLITT, Michael G, EIDELBERG, David

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Dopaminergic Suppression of Brain Deactivation Responses during Sequence Learning by Argyelan, Miklos, Carbon, Maren, Ghilardi, Maria-Felice, Feigin, Andrew, Mattis, Paul, Tang, Chengke, Dhawan, Vijay, Eidelberg, David

“…Cognitive processing is associated with deactivation of the default mode network. The presence of dopaminoceptive neurons in proximity to the medial prefrontal…”
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Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism by Emborg, Marina E, Carbon, Maren, Holden, James E, During, Matthew J, Ma, Yilong, Tang, Chengke, Moirano, Jeffrey, Fitzsimons, Helen, Roitberg, Ben Z, Tuccar, Eray, Roberts, Andrew, Kaplitt, Michael G, Eidelberg, David

“…Parkinson's disease (PD) is associated with increased excitatory activity within the subthalamic nucleus (STN). We sought to inhibit STN output in…”
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Dose- and rate-dependent effects of cocaine on striatal firing related to licking by Tang, Chengke, Mittler, Taliah, Duke, Dawn C, Zhu, Yun, Pawlak, Anthony P, West, Mark O

“…To examine the role of striatal mechanisms in cocaine-induced stereotyped licking, we investigated the acute effects of cocaine on striatal neurons in awake,…”
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Dopamine Cell Implantation in Parkinson's Disease: Long-Term Clinical and 18F-FDOPA PET Outcomes by Ma, Yilong, Tang, Chengke, Chaly, Thomas, Greene, Paul, Breeze, Robert, Fahn, Stanley, Freed, Curt, Dhawan, Vijay, Eidelberg, David

“…We have previously reported the results of a 1-y double-blind, placebo-controlled study of embryonic dopamine cell implantation for Parkinson’s disease. At the…”
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PmWebSpec: An Application to Create and Manage CDISC-Compliant Pharmacometric Analysis Dataset Specifications by Chen, Lu, Dombrowsky, Erin, Boyle, Baylea, Tang, Chengke, Thanneer, Neelima

“…A well-documented pharmacometric (PMx) analysis dataset specification ensures consistency in derivations of the variables, naming conventions, traceability to…”
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Metabolic brain networks associated with cognitive function in Parkinson's disease by Huang, Chaorui, Mattis, Paul, Tang, Chengke, Perrine, Kenneth, Carbon, Maren, Eidelberg, David

“…The motor manifestations of Parkinson's disease (PD) have been linked to an abnormal spatial covariance pattern involving basal ganglia thalamocortical…”
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Network modulation in the treatment of Parkinson's disease by Asanuma, Kotaro, Tang, Chengke, Ma, Yilong, Dhawan, Vijay, Mattis, Paul, Edwards, Christine, Kaplitt, Michael G., Feigin, Andrew, Eidelberg, David

“…It has been proposed that deep brain stimulation (DBS) of the subthalamic nucleus (STN DBS) and dopaminergic therapy ameliorate the symptoms of Parkinson’s…”
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Abnormal regional brain function in Parkinson's disease: truth or fiction? by Ma, Yilong, Tang, Chengke, Moeller, James R., Eidelberg, David

“…Normalization of regional measurements by the global mean is commonly employed to minimize inter-subject variability in functional imaging studies. This…”
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