Search Results - "Tang, Anna A. S."

Targeting Grb2 SH3 Domains with Affimer Proteins Provides Novel Insights into Ras Signalling Modulation by Tang, Anna A S, Macdonald, Andrew, McPherson, Michael J, Tomlinson, Darren C

“…Src homology 3 (SH3) domains play a critical role in mediating protein-protein interactions (PPIs) involved in cell proliferation, migration, and the…”
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Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis by Rawlings, Andrea E, Bramble, Jonathan P, Tang, Anna A S, Somner, Lori A, Monnington, Amy E, Cooke, David J, McPherson, Michael J, Tomlinson, Darren C, Staniland, Sarah S

“…Adhirons are robust, well expressing, peptide display scaffold proteins, developed as an effective alternative to traditional antibody binding proteins for…”
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Affimers targeting proteins in the cardiomyocyte Z-disc: Novel tools that improve imaging of heart tissue by Parker, Francine, Tang, Anna A S, Rogers, Brendan, Carrington, Glenn, Dos Remedios, Cris, Li, Amy, Tomlinson, Darren, Peckham, Michelle

“…Dilated Cardiomyopathy is a common form of heart failure. Determining how this disease affects the structure and organization of cardiomyocytes in the human…”
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Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications by Tiede, Christian, Tang, Anna A. S., Deacon, Sarah E., Mandal, Upasana, Nettleship, Joanne E., Owen, Robin L., George, Suja E., Harrison, David J., Owens, Raymond J., Tomlinson, Darren C., McPherson, Michael J.

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Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications by Tiede, Christian, Tang, Anna A. S., Deacon, Sarah E., Mandal, Upasana, Nettleship, Joanne E., Owen, Robin L., George, Suja E., Harrison, David J., Owens, Raymond J., Tomlinson, Darren C., McPherson, Michael J.

“…We have designed a novel non-antibody scaffold protein, termed Adhiron, based on a phytocystatin consensus sequence. The Adhiron scaffold shows high thermal…”
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Isolation of Artificial Binding Proteins (Affimer Reagents) for Use in Molecular and Cellular Biology by Tang, Anna A S, Tiede, Christian, McPherson, Michael J, Tomlinson, Darren C

“…Artificial binding proteins have been validated as alternatives to antibodies in their use as research reagents in molecular and cellular biology. For example,…”
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Generating and validating renewable affimer protein binding reagents targeting SH2 domains by Heseltine, Sophie J., Billenness, Gregory J., Martin, Heather L, Tiede, Christian, Tang, Anna A.S., Foy, Eleanor, Reddy, Grace, Gibson, Naomi, Johnson, Matt, Webb, Michael E., McPherson, Michael J., Tomlinson, Darren C.

“…Despite SH2 domains, being pivotal in protein interactions linked to various diseases like cancer, we lack specific research tools for intracellular assays…”
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Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesisElectronic supplementary information (ESI) available: Detailed experimental methods, supporting experimental data, and details of the molecular dynamics study. See DOI: 10.1039/c5sc01472g by Rawlings, Andrea E, Bramble, Jonathan P, Tang, Anna A. S, Somner, Lori A, Monnington, Amy E, Cooke, David J, McPherson, Michael J, Tomlinson, Darren C, Staniland, Sarah S

“…Adhirons are robust, well expressing, peptide display scaffold proteins, developed as an effective alternative to traditional antibody binding proteins for…”
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Phage display selected magnetite interacting Adhirons for shape controlled nanoparticle synthesis† †Electronic supplementary information (ESI) available: Detailed experimental methods, supporting experimental data, and details of the molecular dynamics study. See DOI: 10.1039/c5sc01472g by Rawlings, Andrea E., Bramble, Jonathan P., Tang, Anna A. S., Somner, Lori A., Monnington, Amy E., Cooke, David J., McPherson, Michael J., Tomlinson, Darren C., Staniland, Sarah S.

“…Biopanning was used to generate novel artificial binding proteins which are able to control the formation of synthetic cubic nanoparticles of magnetite…”
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New technique for nanoparticle capillary electrophoresis/microfluidic chip and its uses in enantioselective separation by Chen, Jie, Ding, Guosheng, Yue, Chunyue, Tang, Anna

“…Nanoparticles have been widely used in separation science due to their large specific surface area and good biocompatibility. Nanoparticle capillary…”
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Preparation of norvancomycin-bonded chiral silica monolithic column for capillary electrochromatography and its applications by Ding, Guosheng, Tang, Anna

“…Silica-based monolithic column with high rigidity and good permeability was prepared by a modified sol-gel technology, characterized by shorter fabrication…”
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