Search Results - "Taneja, Bhupesh"

Genome Analysis of Staphylococcus capitis TE8 Reveals Repertoire of Antimicrobial Peptides and Adaptation Strategies for Growth on Human Skin by Kumar, Rohit, Jangir, Pramod Kumar, Das, Jhumki, Taneja, Bhupesh, Sharma, Rakesh

“…Staphylococcus capitis TE8 was isolated from skin surface of a healthy human foot, and exhibited a strong antibacterial activity against Gram-positive…”
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EnsembleSeq: a workflow towards real-time, rapid, and simultaneous multi-kingdom-amplicon sequencing for holistic and resource-effective microbiome research at scale by Nagpal, Sunil, Mande, Sharmila S, Hooda, Harish, Dutta, Usha, Taneja, Bhupesh

“…Bacterial communities are often concomitantly present with numerous microorganisms in the human body and other natural environments. Amplicon-based microbiome…”
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A Dual-Plasmid-Based CRISPR/Cas9-Mediated Strategy Enables Targeted Editing of pH Regulatory Gene pacC in a Clinical Isolate of Trichophyton rubrum by Dey, Sanchita Sanchaya, Ramalingam, Sivaprakash, Taneja, Bhupesh

“…is the most prevalent causative agent responsible for 80-90% of all known superficial fungal infections in humans, worldwide. Limited available methods for…”
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Whole genome sequences of two Trichophyton indotineae clinical isolates from India emerging as threats during therapeutic treatment of dermatophytosis by Kumar, Pawan, Das, Shukla, Tigga, Richa, Pandey, Rajesh, Bhattacharya, S. N., Taneja, Bhupesh

“…In the current study, we report the genome sequence of two different clinical isolates from India, Trichophyton indotineae UCMS-IGIB-CI12 and Trichophyton…”
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Loss of U1498 methylation in 16S rRNA by RsmE methyltransferase associates its role with aminoglycoside resistance in mycobacteria by Bijpuria, Shipra, Sharma, Rakesh, Taneja, Bhupesh

“…•First evidence of association of U1498 methylation with antibiotic response.•Deletion of RsmE leads to at least two-fold increase in aminoglycoside minimum…”
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Structural and Functional Characterization of Rv2966c Protein Reveals an RsmD-like Methyltransferase from Mycobacterium tuberculosis and the Role of Its N-terminal Domain in Target Recognition by Kumar, Atul, Saigal, Kashyap, Malhotra, Ketan, Sinha, Krishna Murari, Taneja, Bhupesh

“…Nine of ten methylated nucleotides of Escherichia coli 16 S rRNA are conserved in Mycobacterium tuberculosis. All the 10 different methyltransferases are known…”
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Integration host factor of Mycobacterium tuberculosis, mIHF, compacts DNA by a bending mechanism by Mishra, Arpit, Vij, Manika, Kumar, Dhirendra, Taneja, Vibha, Mondal, Anupam Kumar, Bothra, Ankur, Rao, Vivek, Ganguli, Munia, Taneja, Bhupesh

“…The bacterial chromosomal DNA is folded into a compact structure called as 'nucleoid' so that the bacterial genome can be accommodated inside the cell. The…”
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Correction to: Whole genome sequences of two Trichophyton indotineae clinical isolates from India emerging as threats during therapeutic treatment of dermatophytosis by Kumar, Pawan, Das, Shukla, Tigga, Richa, Pandey, Rajesh, Bhattacharya, S. N., Taneja, Bhupesh

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Topoisomerase V Relaxes Supercoiled DNA by a Constrained Swiveling Mechanism by Taneja, Bhupesh, Schnurr, Bernhard, Slesarev, Alexei, Marko, John F., Mondragón, Alfonso

“…Topoisomerase V is a type I topoisomerase without structural or sequence similarities to other topoisomerases. Although it belongs to the type I subfamily of…”
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Physical Properties of Intact Proteins May Predict Allergenicity or Lack Thereof by Singh, Suchita, Taneja, Bhupesh, Salvi, Sundeep Santosh, Agrawal, Anurag

“…Background: Predicting the allergenicity of proteins is challenging. We considered the possibility that the properties of the intact protein that may alter the…”
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Three-dimensional structure of a mycobacterial oligoribonuclease reveals a unique C-terminal tail that stabilizes the homodimer by Badhwar, Pooja, Khan, Sabab Hasan, Taneja, Bhupesh

“…Oligoribonucleases (Orns) are highly conserved DnaQ-fold 3′-5′ exoribonucleases that have been found to carry out the last step of cyclic-di-GMP (c-di-GMP)…”
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Structural investigation and gene deletion studies of mycobacterial oligoribonuclease reveal modulation of c-di-GMP-mediated phenotypes by Badhwar, Pooja, Ahmad, Iftekhar, Sharma, Rakesh, Taneja, Bhupesh

“…Cyclic-di-GMP (c-di-GMP) is a ubiquitous bacterial second messenger required for normal physiology as well as survival under hypoxic and reductive stress…”
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MarkerML – Marker Feature Identification in Metagenomic Datasets Using Interpretable Machine Learning by Nagpal, Sunil, Singh, Rohan, Taneja, Bhupesh, Mande, Sharmila S.

“…[Display omitted] •Metagenomic marker features are conventionally identified by ‘class comparisons’ or through black-box machine learnt models.•MarkerML is…”
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Structural and thermodynamic characterization of a highly stable conformation of Rv2966c, a 16S rRNA methyltransferase, at low pH by Khan, Sabab Hasan, Bijpuria, Shipra, Maurya, Anjali, Taneja, Bhupesh

“…Rv2966c is a highly specific methyltransferase that methylates G966 at the N2 position in 16S rRNA of mycobacterial ribosome and can be secreted inside the…”
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Conserved structural features and sequence patterns in the GroES fold family by Taneja, Bhupesh, Mande, Shekhar C.

“…An irregular, all β-class of proteins, comprising members of the chaperonin-10, quinone oxidoreductase, glucose dehydrogenase and alcohol dehydrogenase…”
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Biophysical Characterization of the C‑Terminal Tail of T. rubrum PacC Reveals an Inherent Intrinsically Disordered Structure with pH-Induced Structural Plasticity by Dey, Sanchita Sanchaya, Chakraborty, Rahul, Taneja, Bhupesh

“…PacC is a key transcriptional regulator of human pathogenic fungus Trichophyton rubrum with pivotal roles in pH homeostasis and virulence. We report the first…”
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A Dual-Plasmid-Based CRISPR/Cas9-Mediated Strategy Enables Targeted Editing of pH Regulatory Gene IpacC/I in a Clinical Isolate of ITrichophyton rubrum/I by Dey, Sanchita Sanchaya, Ramalingam, Sivaprakash, Taneja, Bhupesh

“…Trichophyton rubrum is the most prevalent causative agent responsible for 80-90% of all known superficial fungal infections in humans, worldwide. Limited…”
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Insights into Changing Dermatophyte Spectrum in India Through Analysis of Cumulative 161,245 Cases Between 1939 and 2021 by Kumar, Pawan, Ramachandran, S., Das, Shukla, Bhattacharya, S. N., Taneja, Bhupesh

“…Dermatophytosis is one of the most common superficial infections of the skin affecting nearly one-fifth of the world population at any given time. With nearly…”
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The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis by Kumar, Atul, Kumar, Santosh, Taneja, Bhupesh

“…U1498 of 16S rRNA plays an important role in translation fidelity as well as in antibiotic response. U1498 is present in a methylated form in the decoding…”
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Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases by Srivastav, Rajpal, Kumar, Dilip, Grover, Amit, Singh, Ajit, Manjasetty, Babu A, Sharma, Rakesh, Taneja, Bhupesh

“…DHH superfamily includes RecJ, nanoRNases (NrnA), cyclic nucleotide phosphodiesterases and pyrophosphatases. In this study, we have carried out in vitro and in…”
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