Search Results - "Taneishi, Kei"

Autoencoder-Based Detection of Dynamic Allostery Triggered by Ligand Binding Based on Molecular Dynamics by Tsuchiya, Yuko, Taneishi, Kei, Yonezawa, Yasushige

“…Dynamic allostery on proteins, triggered by regulator binding or chemical modifications, transmits information from the binding site to distant regions,…”
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Autoencoder-based detection of the residues involved in G protein-coupled receptor signaling by Tsuchiya, Yuko, Taneishi, Kei, Yonezawa, Yasushige

“…Regulator binding and mutations alter protein dynamics. The transmission of the signal of these alterations to distant sites through protein motion results in…”
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CGBVS‐DNN: Prediction of Compound‐protein Interactions Based on Deep Learning by Hamanaka, Masatoshi, Taneishi, Kei, Iwata, Hiroaki, Ye, Jun, Pei, Jianguo, Hou, Jinlong, Okuno, Yasushi

“…Computational prediction of compound‐protein interactions (CPIs) is of great importance for drug design as the first step in in‐silico screening. We previously…”
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Development and validation of a set of six adaptable prognosis prediction (SAP) models based on time-series real-world big data analysis for patients with cancer receiving chemotherapy: A multicenter case crossover study by Uneno, Yu, Taneishi, Kei, Kanai, Masashi, Okamoto, Kazuya, Yamamoto, Yosuke, Yoshioka, Akira, Hiramoto, Shuji, Nozaki, Akira, Nishikawa, Yoshitaka, Yamaguchi, Daisuke, Tomono, Teruko, Nakatsui, Masahiko, Baba, Mika, Morita, Tatsuya, Matsumoto, Shigemi, Kuroda, Tomohiro, Okuno, Yasushi, Muto, Manabu

“…We aimed to develop an adaptable prognosis prediction model that could be applied at any time point during the treatment course for patients with cancer…”
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Adjuvant chemotherapy improves survival of patients with high-risk upper urinary tract urothelial carcinoma: a propensity score-matched analysis by Fujita, Kazutoshi, Taneishi, Kei, Inamoto, Teruo, Ishizuya, Yu, Takada, Shingo, Tsujihata, Masao, Tanigawa, Go, Minato, Noriko, Nakazawa, Shigeaki, Takada, Tsuyoshi, Iwanishi, Toshichika, Uemura, Motohide, Okuno, Yasushi, Azuma, Haruhito, Norio, Nonomura

“…The purposes of this study were to determine whether adjuvant chemotherapy (AC) improved the prognosis of patients with high-risk upper urinary tract…”
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Association between UGT1A12828 genotype and lung cancer in the Japanese population by Nishikawa, Yoshitaka, Kanai, Masashi, Narahara, Maiko, Tamon, Akiko, Brown, J. B., Taneishi, Kei, Nakatsui, Masahiko, Okamoto, Kazuya, Uneno, Yu, Yamaguchi, Daisuke, Tomono, Teruko, Mori, Yukiko, Matsumoto, Shigemi, Okuno, Yasushi, Muto, Manabu

“…Background Lung cancer is the leading cause of cancer death and is closely linked to tobacco smoking. Genetic polymorphisms in genes that encode enzymes…”
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Structure-based analyses of gut microbiome-related proteins by neural networks and molecular dynamics simulations by Taneishi, Kei, Tsuchiya, Yuko

“…An imbalance in the gut microbiome is linked to immune disorders, such as autoimmune, allergic, and chronic inflammatory disorders. Elucidation of disease…”
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On computational complexity of graph inference from counting by Fazekas, Szilárd Zsolt, Ito, Hiro, Okuno, Yasushi, Seki, Shinnosuke, Taneishi, Kei

“…In de novo drug design, chemical compounds are quantitized as real-valued vectors called chemical descriptors, and an optimization algorithm runs on known…”
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Combination of host immune metabolic biomarkers for the PD-1 blockade cancer immunotherapy by Hatae, Ryusuke, Chamoto, Kenji, Kim, Young Hak, Sonomura, Kazuhiro, Taneishi, Kei, Kawaguchi, Shuji, Yoshida, Hironori, Ozasa, Hiroaki, Sakamori, Yuichi, Akrami, Maryam, Fagarasan, Sidonia, Masuda, Izuru, Okuno, Yasushi, Matsuda, Fumihiko, Hirai, Toyohiro, Honjo, Tasuku

“…BACKGROUNDCurrent clinical biomarkers for the programmed cell death 1 (PD-1) blockade therapy are insufficient because they rely only on the tumor properties,…”
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Establishment of a terminal prognosis prediction model by applying time series analysis to real-world data by Uneno, Yu, Taneishi, Kei, Kanai, Masashi, Tamon, Akiko, Okamoto, Kazuya, Nishikawa, Yoshitaka, Brown, J.B., Matsumoto, Shigemi, Okuno, Yasushi, Muto, Manabu

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Development and validation of a set of six adaptable prognosis prediction by Uneno, Yu, Taneishi, Kei, Kanai, Masashi, Okamoto, Kazuya, Yamamoto, Yosuke, Yoshioka, Akira, Hiramoto, Shuji, Nozaki, Akira, Nishikawa, Yoshitaka, Yamaguchi, Daisuke, Tomono, Teruko, Nakatsui, Masahiko, Baba, Mika, Morita, Tatsuya, Matsumoto, Shigemi, Kuroda, Tomohiro, Okuno, Yasushi, Muto, Manabu

“…Background We aimed to develop an adaptable prognosis prediction model that could be applied at any time point during the treatment course for patients with…”
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GLIDA: GPCR-ligand database for chemical genomic drug discovery by Okuno, Yasushi, Yang, Jiyoon, Taneishi, Kei, Yabuuchi, Hiroaki, Tsujimoto, Gozoh

“…G-protein coupled receptors (GPCRs) represent one of the most important families of drug targets in pharmaceutical development. GPCR-LIgand DAtabase (GLIDA) is…”
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