Search Results - "Tandler, Bernard"

Mitochondrial Dysfunction and Myocardial Ischemia-Reperfusion: Implications for Novel Therapies by Lesnefsky, Edward J, Chen, Qun, Tandler, Bernard, Hoppel, Charles L

“…Mitochondria have emerged as key participants in and regulators of myocardial injury during ischemia and reperfusion. This review examines the sites of damage…”
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Dynamic organization of mitochondria in human heart and in myocardial disease by Hoppel, Charles L., Tandler, Bernard, Fujioka, Hisashi, Riva, Alessandro

“…Heart mitochondria, which, depending on their location within cardiomyofibers, are classified as either subsarcolemmal or interfibrillar, are the major sources…”
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VDAC proteomics: Post-translation modifications by Kerner, Janos, Lee, Kwangwon, Tandler, Bernard, Hoppel, Charles L.

“…Voltage-dependent anion channels are abundant mitochondrial outer membrane proteins expressed in three isoforms, VDAC1-3, and are considered as “mitochondrial…”
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Blockade of Electron Transport during Ischemia Protects Cardiac Mitochondria by Lesnefsky, Edward J, Chen, Qun, Moghaddas, Shadi, Hassan, Medhat O, Tandler, Bernard, Hoppel, Charles L

“…Subsarcolemmal mitochondria sustain progressive damage during myocardial ischemia. Ischemia decreases the content of the mitochondrial phospholipid cardiolipin…”
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Mitochondrial Dysfunction in Cardiac Disease: Ischemia–Reperfusion, Aging, and Heart Failure by Lesnefsky, Edward J., Moghaddas, Shadi, Tandler, Bernard, Kerner, Janos, Hoppel, Charles L.

“…Mitochondria contribute to cardiac dysfunction and myocyte injury via a loss of metabolic capacity and by the production and release of toxic products. This…”
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Morphological Pathways of Mitochondrial Division by Tandler, Bernard, Hoppel, Charles L, Mears, Jason A

“…Mitochondrial fission is essential for distributing cellular energy throughout cells and for isolating damaged regions of the organelle that are targeted for…”
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Structural differences in two biochemically defined populations of cardiac mitochondria by Riva, Alessandro, Tandler, Bernard, Loffredo, Felice, Vazquez, Edwin, Hoppel, Charles

“…To determine whether there are structural differences in two topologically separated, biochemically defined mitochondrial populations in rat heart myocytes,…”
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Dietary and flight energetic adaptations in a salivary gland transcriptome of an insectivorous bat by Phillips, Carleton J, Phillips, Caleb D, Goecks, Jeremy, Lessa, Enrique P, Sotero-Caio, Cibele G, Tandler, Bernard, Gannon, Michael R, Baker, Robert J

“…We hypothesized that evolution of salivary gland secretory proteome has been important in adaptation to insectivory, the most common dietary strategy among…”
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Ischemia, rather than reperfusion, inhibits respiration through cytochrome oxidase in the isolated, perfused rabbit heart: role of cardiolipin by Lesnefsky, Edward J, Chen, Qun, Slabe, Thomas J, Stoll, Maria S K, Minkler, Paul E, Hassan, Medhat O, Tandler, Bernard, Hoppel, Charles L

“…Ischemia and reperfusion result in mitochondrial dysfunction, with decreases in oxidative capacity, loss of cytochrome c, and generation of reactive oxygen…”
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Mitochondria of human Leydig cells as seen by high resolution scanning electron microscopy by Riva, Alessandro, Tandler, Bernard, Ushiki, Tatsuo, Usai, Paolo, Isola, Raffaella, Conti, Gabriele, Loy, Francesco, Hoppel, Charles L.

“…The three-dimensional ultrastructure of over 1000 mitochondria in human Leydig cells (from twelve sexually mature patients) was examined by high resolution…”
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Mitochondria in cardiac hypertrophy and heart failure by Rosca, Mariana G, Tandler, Bernard, Hoppel, Charles L

“…Abstract Heart failure (HF) frequently is the unfavorable outcome of pathological heart hypertrophy. In contrast to physiological cardiac hypertrophy, which…”
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The Malonyl-CoA-sensitive Form of Carnitine Palmitoyltransferase Is Not Localized Exclusively in the Outer Membrane of Rat Liver Mitochondria by Hoppel, Charles L., Kerner, Janos, Turkaly, Peter, Turkaly, Julia, Tandler, Bernard

“…The data used to support the idea that malonyl-coenzyme A (CoA)-sensitive carnitine palmitoyltransferase (CPT-I) is localized on the outer mitochondrial…”
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Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans by Axelrod, Christopher L., Fealy, Ciaran E., Erickson, Melissa L., Davuluri, Gangarao, Fujioka, Hisashi, Dantas, Wagner S., Huang, Emily, Pergola, Kathryn, Mey, Jacob T., King, William T., Mulya, Anny, Hsia, Daniel, Burguera, Bartolome, Tandler, Bernard, Hoppel, Charles L., Kirwan, John P.

“…A diminution in skeletal muscle mitochondrial function due to ectopic lipid accumulation and excess nutrient intake is thought to contribute to insulin…”
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Cardiac mitochondrial structure and function in tafazzin-knockdown mice by Kim, Junhwan, Lee, Kwangwon, Fujioka, Hisashi, Tandler, Bernard, Hoppel, Charles L

“…Mutations in the tafazzin gene are the basis of Barth syndrome. The tafazzin protein is responsible for the synthesis of cardiolipin. Doxycycline-induced…”
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Very low-magnification transmission electron microscopy by Tandler, Bernard, Slabe, Thomas J.

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Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics by King, William T., Axelrod, Christopher L., Zunica, Elizabeth R.M., Noland, Robert C., Davuluri, Gangarao, Fujioka, Hisashi, Tandler, Bernard, Pergola, Kathryn, Hermann, Gerlinda E., Rogers, Richard C., López-Domènech, Sandra, Dantas, Wagner S., Stadler, Krisztian, Hoppel, Charles L., Kirwan, John P.

“…Mitochondria undergo continuous cycles of fission and fusion to promote inheritance, regulate quality control, and mitigate organelle stress. More recently,…”
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Innovations that changed Mammalogy: field fixation for transmission electron microscopy (TEM) by Phillips, Carleton J., Tandler, Bernard, Timm, Robert M., McLaren, Suzanne B., Genoways, Hugh H.

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Ultrastructure of the submandibular gland of the rare white-winged vampire bat, Diaemus youngi by Tandler, Bernard, Phillips, Carleton J

“…The submandibular gland of the white-winged vampire bat, Diaemus youngi, was examined by electron microscopy. Unlike typical submandibular glands, those in…”
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Mitochondrial Division in Rat Cardiomyocytes: An Electron Microscope Study by Fujioka, Hisashi, Tandler, Bernard, Hoppel, Charles L.

“…In cardiomyocytes of rats, two distinct mitochondrial division processes are in operation. The predominant process involves extension of a single crista until…”
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Mitochondrial Dysfunction in Cardiovascular Aging by Hoppel, Charles L, Lesnefsky, Edward J, Chen, Qun, Tandler, Bernard

“…Mitochondria are the prime source of ATP in cardiomyocytes. Impairment of mitochondrial metabolism results in damage to existing proteins and DNA. Such…”
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