Effects of the nuclear genome on selective transmission of mitochondrial DNA in Drosophila

In mitochondrial DNA (mtDNA) heteroplasmy in Drosophila, we previously reported that mtDNA was selectively transmitted depending on temperature (Matsuura et al., 1991). To investigate the effects of nuclear genome on the temperature-dependent transmission, two sets of heteroplasmy were constructed b...

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Bibliographic Details
Published in:	Genes & Genetic Systems Vol. 72; no. 3; pp. 119 - 123
Main Authors:	Matsuura, Etsuko T., Tanaka, Yuko T., Yamamoto, Noriko
Format:	Journal Article
Language:	English
Published:	Japan The Genetics Society of Japan 01-06-1997 Japan Science and Technology Agency
Subjects:	Animals DNA, Mitochondrial - genetics Drosophila - genetics Drosophila melanogaster - genetics Gene Expression Regulation Nuclear Transfer Techniques Species Specificity Temperature
Online Access:	Get full text
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Summary:	In mitochondrial DNA (mtDNA) heteroplasmy in Drosophila, we previously reported that mtDNA was selectively transmitted depending on temperature (Matsuura et al., 1991). To investigate the effects of nuclear genome on the temperature-dependent transmission, two sets of heteroplasmy were constructed by germ-plasm transplantation, and changes in the relative proportion of two types of mtDNA were examined at 19°C and 25°C. In heteroplasmy possessing D. melanogaster and D. mauritiana mtDNA, two different nuclear genomes of D. melanogaster were examined after reciprocally substituting the nuclear genomes. In heteroplasmy possessing D. simulans and D. mauritiana mtDNA, nuclear genomes of D. melanogaster, D. simulans and D. mauritiana were used. For each set of mtDNA combination, the modes of temperature-dependent transmission of mtDNA differed according to the nuclear genome used. From these and our previous results (Matsuura et al., 1991; Tsujimoto et al., 1991), it is clear that the temperature-dependent transmission of mtDNA is affected by nuclear genome. This suggests that the nuclear genome is involved in determining the temperature-dependency of mtDNA transmission.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	1341-7568 1880-5779
DOI:	10.1266/ggs.72.119