Search Results - "Tanaka, Yukinori"
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Differential expression of CD11c defines two types of tissue-resident macrophages with different origins in steady-state salivary glands
Published in Scientific reports (18-01-2022)“…Gland macrophages are primed for gland development and functions through interactions within their niche. However, the phenotype, ontogeny, and function of…”
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2
Lipopolysaccharide Priming Exacerbates Anaphylatoxin C5a-Induced Anaphylaxis in Mice
Published in Biological & pharmaceutical bulletin (01-03-2023)“…Anaphylaxis is a serious allergic or hypersensitivity reaction with a sudden onset that can be life-threatening or fatal. Previous studies have highlighted two…”
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3
Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements
Published in Journal of industrial microbiology & biotechnology (01-02-2014)“…Since bacteria were found to contain genes encoding enzymes that synthesize a plethora of potential secondary metabolites, interest has grown in the activation…”
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4
Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp
Published in Applied and Environmental Microbiology (01-06-2015)“…Antibiotics have either bactericidal or bacteriostatic activity. However, they also induce considerable gene expression in bacteria when used at subinhibitory…”
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5
Activation and Products of the Cryptic Secondary Metabolite Biosynthetic Gene Clusters by Rifampin Resistance (rpoB) Mutations in Actinomycetes
Published in Journal of Bacteriology (01-07-2013)“…A subset of rifampin resistance (rpoB) mutations result in the overproduction of antibiotics in various actinomycetes, including Streptomyces,…”
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6
PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling
Published in Frontiers in immunology (09-04-2020)“…Arginine methylation is a post-translational modification that regulates many biological processes. However, the role of arginine methylation in immune cells…”
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7
Migratory dendritic cells in skin-draining lymph nodes have nickel-binding capabilities
Published in Scientific reports (19-03-2020)“…Nickel (Ni) is the most frequent metal allergen and induces Th1-dependent type-IV allergies. In local skin, epidermal Langerhans cells (LCs) and/or dermal…”
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8
Rare earth elements activate the secondary metabolite–biosynthetic gene clusters in Streptomyces coelicolor A3(2)
Published in Journal of antibiotics (01-08-2010)“…Genome sequencing projects have revealed many biosynthesis gene clusters for the production of as-yet unknown secondary metabolites, especially in…”
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9
Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii
Published in Bioscience, biotechnology, and biochemistry (01-08-2017)“…Ribosome engineering has been widely utilized for strain improvement, especially for the activation of bacterial secondary metabolism. This study assessed…”
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10
IL-33 induces histidine decarboxylase, especially in c-kit+ cells and mast cells, and roles of histamine include negative regulation of IL-33-induced eosinophilia
Published in Inflammation research (01-03-2023)“…Objective and methods IL-33 is present in endothelial, epithelial, and fibroblast-like cells and released upon cell injury. IL-33 reportedly induces mast-cell…”
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Activation of Antibiotic Production in Bacillus spp. by Cumulative Drug Resistance Mutations
Published in Antimicrobial agents and chemotherapy (01-12-2015)“…Bacillus subtilis strains produce a wide range of antibiotics, including ribosomal and nonribosomal peptide antibiotics, as well as bacilysocin and…”
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Metabolic perturbation to enhance polyketide and nonribosomal peptide antibiotic production using triclosan and ribosome-targeting drugs
Published in Applied microbiology and biotechnology (01-06-2017)“…Although transcriptional activation of pathwayspecific positive regulatory genes and/or biosynthetic genes is primarily important for enhancing secondary…”
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13
Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria
Published in Molecular microbiology (01-02-2007)“…Streptomycin has been an important drug for the treatment of tuberculosis since its discovery in 1944. But numerous strains of Mycobacterium tuberculosis, the…”
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14
CD103+CD11b− salivary gland dendritic cells have antigen cross‐presenting capacity
Published in European journal of immunology (01-02-2017)“…Dendritic cells (DCs) in lymphoid and non‐lymphoid tissues are professional antigen‐presenting cells that are essential for effective immunity and tolerance…”
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15
Enhancement of butanol production by sequential introduction of mutations conferring butanol tolerance and streptomycin resistance
Published in Journal of bioscience and bioengineering (01-10-2017)“…Ribosome engineering, originally applied to Streptomyces lividans, has been widely utilized for strain improvement, especially for the activation of bacterial…”
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Mechanisms underlying the induction of regulatory T cells by sublingual immunotherapy
Published in Journal of oral biosciences (01-06-2019)“…Sublingual immunotherapy (SLIT) is used for the treatment of type 1 allergies, such as allergic rhinitis. SLIT leads to tolerance against allergens possibly…”
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Antibiotic Overproduction by rpsL and rsmG Mutants of Various Actinomycetes
Published in Applied and Environmental Microbiology (01-07-2009)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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18
Combined Drug Resistance Mutations Substantially Enhance Enzyme Production in Paenibacillus agaridevorans
Published in Journal of bacteriology (01-09-2018)“…This study shows that sequential introduction of drug resistance mutations substantially increased enzyme production in The triple mutant YT478 ( Gln225→stop…”
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Improved antibiotic production and silent gene activation in Streptomyces diastatochromogenes by ribosome engineering
Published in Journal of antibiotics (01-05-2016)Get full text
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20
Retained Myogenic Potency of Human Satellite Cells from Torn Rotator Cuff Muscles Despite Fatty Infiltration
Published in The Tohoku Journal of Experimental Medicine (01-01-2018)“…Rotator cuff tears (RCTs) are a common shoulder problem in the elderly that can lead to both muscle atrophy and fatty infiltration due to less physical load…”
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