Search Results - "Tanaka, Yuka"

Antioxidant cinnamaldehyde attenuates UVB-induced photoaging by Tanaka, Yuka, Uchi, Hiroshi, Furue, Masutaka

“…•Cinnamaldehyde inhibits UVB-induced ROS production and DNA damage in keratinocytes.•Cinnamaldehyde attenuates UVB-induced oxidative stress in…”
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Clinical significance of glypican-3-positive circulating tumor cells of hepatocellular carcinoma patients: A prospective study by Hamaoka, Michinori, Kobayashi, Tsuyoshi, Tanaka, Yuka, Mashima, Hiroaki, Ohdan, Hideki

“…The utility of glypican-3 (GPC3) expression for the detection of circulating tumor cells (CTCs) in hepatocellular carcinoma (HCC) patients has not been…”
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Total synthesis of isoneoantimycin by Usuki, Yoshinosuke, Tanaka, Yuka, Morii, Miyu, Satoh, Tetsuya

“…Antimycins are one of the well-known antifungal metabolites produced by bacteria. Neoantimycin and its analogues, the ring-expanded antimycins featuring a…”
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The main oxidative inactivation pathway of the plant hormone auxin by Hayashi, Ken-ichiro, Arai, Kazushi, Aoi, Yuki, Tanaka, Yuka, Hira, Hayao, Guo, Ruipan, Hu, Yun, Ge, Chennan, Zhao, Yunde, Kasahara, Hiroyuki, Fukui, Kosuke

“…Inactivation of the phytohormone auxin plays important roles in plant development, and several enzymes have been implicated in auxin inactivation. In this…”
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Indirubin-pregnane X receptor-JNK axis accelerates skin wound healing by Tanaka, Yuka, Uchi, Hiroshi, Ito, Takamichi, Furue, Masutaka

“…Indirubin is a potent anti-inflammatory phytochemical derived from indigo naturalis. It is also endogenously produced in the intestine and detected in the…”
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Cyto/chemokine profile of in vitro scratched keratinocyte model: Implications of significant upregulation of CCL20, CXCL8 and IL36G in Koebner phenomenon by Furue, Kazuhisa, Ito, Takamichi, Tanaka, Yuka, Yumine, Ayako, Hashimoto-Hachiya, Akiko, Takemura, Masaki, Murata, Maho, Yamamura, Kazuhiko, Tsuji, Gaku, Furue, Masutaka

“…•Pathomechanism of scratch-induced Koebner phenomenon in psoriasis is unknown.•Scracth injury on confluent keratinocytes upregulates CCL20, CXCL8, IL36G and…”
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TLR‐MyD88 signaling blockades inhibit refractory B‐1b cell immune responses to transplant‐related glycan antigens by Sakai, Hiroshi, Tanaka, Yuka, Tanaka, Asuka, Ohdan, Hideki

“…Refractory B cell responses to T cell–independent (TI) carbohydrate antigens (Ags) are critical drivers of rejection reactions to ABO‐incompatible allogeneic…”
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Cotransplantation of preactivated mesenchymal stem cells improves intraportal engraftment of islets by inhibiting liver natural killer cells in mice by Ishida, Nobuki, Ishiyama, Kohei, Saeki, Yoshihiro, Tanaka, Yuka, Ohdan, Hideki

“…The activation of natural killer (NK) cells in the liver inhibits engraftment of intraportally transplanted islets. We attempted to modulate the activity of NK…”
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Masticatory performance of the elderly as seen from differences in occlusal support of residual teeth by Tanaka, Yuka, Shiga, Hiroshi

“…To clarify whether the occlusal state affects the masticatory performance of elderly adults. Elderly women were asked to chew a gummy jelly, and the amount of…”
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Nectin cell adhesion molecule 4 regulates angiogenesis through Src signaling and serves as a novel therapeutic target in angiosarcoma by Tanaka, Yuka, Murata, Maho, Tanegashima, Keiko, Oda, Yoshinao, Ito, Takamichi

“…Angiosarcoma is a rare, life-threatening soft tissue sarcoma with malignant endothelial cells that is mainly found in the skin. Multidisciplinary approaches…”
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Development of PEGylated aspartic acid-modified liposome as a bone-targeting carrier for the delivery of paclitaxel and treatment of bone metastasis by Yamashita, Shugo, Katsumi, Hidemasa, Hibino, Nozomi, Isobe, Yugo, Yagi, Yumiko, Tanaka, Yuka, Yamada, Saki, Naito, Chihiro, Yamamoto, Akira

“…To prevent bone metastasis, we developed polyethylene glycol (PEG)-conjugated aspartic acid (Asp)-modified liposomes (PEG-Asp-Lipo) as a bone-targeting carrier…”
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NECTIN4 Expression in Extramammary Paget's Disease: Implication of a New Therapeutic Target by Murata, Maho, Ito, Takamichi, Tanaka, Yuka, Kaku-Ito, Yumiko, Furue, Masutaka

“…Extramammary Paget's disease (EMPD) is a rare skin cancer arising in the anogenital area. Most EMPD tumors remain dormant as in situ lesions, but the outcomes…”
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FOXM1: a new therapeutic target of extramammary Paget disease by Ito, Takamichi, Tanaka, Yuka, Kaku-Ito, Yumiko, Oda, Yoshinao, Nakahara, Takeshi

“…Extramammary Paget disease (EMPD) is a rare skin cancer that primarily affects older individuals predominantly in areas with apocrine sweat glands. Although…”
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NECTIN4: A Novel Therapeutic Target for Melanoma by Tanaka, Yuka, Murata, Maho, Shen, Che-Hung, Furue, Masutaka, Ito, Takamichi

“…Malignant melanoma is the most common lethal skin cancer and causes death in a short time when metastasized. Although BRAF inhibitors (BRAFi) have greatly…”
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Chemical inhibition of the auxin inactivation pathway uncovers the roles of metabolic turnover in auxin homeostasis by Fukui, Kosuke, Arai, Kazushi, Tanaka, Yuka, Aoi, Yuki, Kukshal, Vandna, Jez, Joseph M, Kubes, Martin F, Napier, Richard, Zhao, Yunde, Kasahara, Hiroyuki, Hayashi, Ken-Ichiro

“…The phytohormone auxin, indole-3-acetic acid (IAA), plays a prominent role in plant development. Auxin homeostasis is coordinately regulated by auxin…”
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Abemaciclib, a CDK4/6 inhibitor, exerts preclinical activity against aggressive germinal center‐derived B‐cell lymphomas by Tanaka, Yuka, Momose, Shuji, Tabayashi, Takayuki, Sawada, Keisuke, Yamashita, Takahisa, Higashi, Morihiro, Sagawa, Morihiko, Tokuhira, Michihide, Rosenwald, Andreas, Kizaki, Masahiro, Tamaru, Jun‐ichi

“…The revised WHO classification newly defined the entities “High‐grade B‐cell lymphoma with MYC and BCL2, and/or BCL6 rearrangements (HGBL‐DH/TH)” and “HGBL,…”
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Quantitative monitoring of ubiquitination/deubiquitination reaction cycles by 18O-incorporation by Tanaka, Yuka, Morimoto, Daichi, Walinda, Erik, Sugase, Kenji, Shirakawa, Masahiro

“…Ubiquitination is one of the major post-translational modifications and entails conjugation of ubiquitin molecules to target proteins. To make free ubiquitin…”
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The auxin-inducible degron 2 (AID2) system enables controlled protein knockdown during embryogenesis and development in Caenorhabditis elegans by Negishi, Takefumi, Kitagawa, Saho, Horii, Natsumi, Tanaka, Yuka, Haruta, Nami, Sugimoto, Asako, Sawa, Hitoshi, Hayashi, Ken-ichiro, Harata, Masahiko, Kanemaki, Masato T

“…Abstract Targeted protein degradation using the auxin-inducible degron (AID) system is garnering attention in the research field of Caenorhabditis elegans,…”
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Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice by Yano, Takuya, Ohira, Masahiro, Nakano, Ryosuke, Tanaka, Yuka, Ohdan, Hideki

“…Liver-resident natural killer (NK) cells express TNF-related apoptosis-inducing ligand (TRAIL), a critical molecule for NK cell-mediated tumor cell killing. We…”
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Nectin-4: a Novel Therapeutic Target for Skin Cancers by Hashimoto, Hiroki, Tanaka, Yuka, Murata, Maho, Ito, Takamichi

“…Opinion statement Nectin-4 is a tumor-associated antigen that is highly expressed on various cancer cells, and it has been further proposed to have roles in…”
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