Search Results - "Tanaka, U"
-
1
Kinetochore-microtubule interactions: steps towards bi-orientation
Published in The EMBO journal (15-12-2010)“…Eukaryotic cells segregate their chromosomes accurately to opposite poles during mitosis, which is necessary for maintenance of their genetic integrity. This…”
Get full text
Journal Article -
2
Aurora B-INCENP Localization at Centromeres/Inner Kinetochores Is Required for Chromosome Bi-orientation in Budding Yeast
Published in Current biology (06-05-2019)“…For proper chromosome segregation in mitosis, sister kinetochores must interact with microtubules from opposite spindle poles (chromosome bi-orientation) [1,…”
Get full text
Journal Article -
3
Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment
Published in Molecular cell (06-06-2013)“…Centromeres play several important roles in ensuring proper chromosome segregation. Not only do they promote kinetochore assembly for microtubule attachment,…”
Get full text
Journal Article -
4
Kinetochore–microtubule interactions: the means to the end
Published in Current opinion in cell biology (01-02-2008)“…Kinetochores are proteinaceous complexes containing dozens of components; they are assembled at centromeric DNA regions and provide the major microtubule…”
Get full text
Journal Article -
5
Smc3 Deacetylation by Hos1 Facilitates Efficient Dissolution of Sister Chromatid Cohesion during Early Anaphase
Published in Molecular cell (02-11-2017)“…Cohesins establish sister chromatid cohesion during S phase and are removed when cohesin Scc1 is cleaved by separase at anaphase onset. During this process,…”
Get full text
Journal Article -
6
Kinetochore–microtubule error correction is driven by differentially regulated interaction modes
Published in Nature cell biology (01-04-2015)“…For proper chromosome segregation, sister kinetochores must interact with microtubules from opposite spindle poles (bi-orientation). To establish…”
Get full text
Journal Article -
7
SWAP, SWITCH, and STABILIZE: Mechanisms of Kinetochore-Microtubule Error Correction
Published in Cells (Basel, Switzerland) (26-04-2022)“…For correct chromosome segregation in mitosis, eukaryotic cells must establish chromosome biorientation where sister kinetochores attach to microtubules…”
Get full text
Journal Article -
8
Cnn1 inhibits the interactions between the KMN complexes of the yeast kinetochore
Published in Nature cell biology (01-06-2012)“…Kinetochores attach the replicated chromosomes to the mitotic spindle and orchestrate their transmission to the daughter cells. Kinetochore–spindle binding and…”
Get full text
Journal Article -
9
Molecular Mechanisms of Microtubule-Dependent Kinetochore Transport toward Spindle Poles
Published in The Journal of cell biology (16-07-2007)“…In mitosis, kinetochores are initially captured by the lateral sides of single microtubules and are subsequently transported toward spindle poles. Mechanisms…”
Get full text
Journal Article -
10
Live-Cell Imaging Reveals Replication of Individual Replicons in Eukaryotic Replication Factories
Published in Cell (30-06-2006)“…Faithful DNA replication ensures genetic integrity in eukaryotic cells, but it is still obscure how replication is organized in space and time within the…”
Get full text
Journal Article -
11
Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis
Published in eLife (03-07-2019)“…To ensure proper segregation during mitosis, chromosomes must be efficiently captured by spindle microtubules and subsequently aligned on the mitotic spindle…”
Get full text
Journal Article -
12
High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination
Published in Cell reports (Cambridge) (27-11-2013)“…Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution…”
Get full text
Journal Article -
13
Mps1 Kinase Promotes Sister-Kinetochore Bi-orientation by a Tension-Dependent Mechanism
Published in Current biology (18-12-2007)“…Segregation of sister chromatids to opposite spindle poles during anaphase is dependent on the prior capture of sister kinetochores by microtubules extending…”
Get full text
Journal Article -
14
Detection of parametric resonance of trapped ions for micromotion compensation
Published in Applied physics. B, Lasers and optics (01-11-2011)“…We have detected excess micromotion of trapped ions by modulating the trapping voltage. This radio-frequency (rf) modulation induces parametric resonance and…”
Get full text
Journal Article -
15
The Ndc80 Loop Region Facilitates Formation of Kinetochore Attachment to the Dynamic Microtubule Plus End
Published in Current biology (08-02-2011)“…Proper chromosome segregation in mitosis relies on correct kinetochore-microtubule (KT-MT) interactions. The KT initially interacts with the lateral surface of…”
Get full text
Journal Article -
16
Molecular mechanisms of kinetochore capture by spindle microtubules
Published in Nature (21-04-2005)“…For high-fidelity chromosome segregation, kinetochores must be properly captured by spindle microtubules, but the mechanisms underlying initial kinetochore…”
Get full text
Journal Article -
17
Discovery of an Unconventional Centromere in Budding Yeast Redefines Evolution of Point Centromeres
Published in Current biology (03-08-2015)“…Centromeres are the chromosomal regions promoting kinetochore assembly for chromosome segregation. In many eukaryotes, the centromere consists of up to mega…”
Get full text
Journal Article -
18
Stochastic association of neighboring replicons creates replication factories in budding yeast
Published in The Journal of cell biology (30-09-2013)“…Inside the nucleus, DNA replication is organized at discrete sites called replication factories, consisting of DNA polymerases and other replication proteins…”
Get full text
Journal Article -
19
Micromotion compensation in a surface electrode trap by parametric excitation of trapped ions
Published in Applied physics. B, Lasers and optics (01-06-2012)“…We report a surface electrode trap with a relatively large trap depth (0.6–1.0 eV). The trap electrodes are formed by gold plating an alumina substrate…”
Get full text
Journal Article -
20
Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex
Published in The EMBO journal (15-11-2001)“…Yeast spindle pole bodies (SPBs) duplicate once per cell cycle by a conservative mechanism resulting in a pre‐existing ‘old’ and a newly formed SPB. The two…”
Get full text
Journal Article