Search Results - "Tanaka, Tomofumi"

Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes by Tohyama, Shugo, Hattori, Fumiyuki, Sano, Motoaki, Hishiki, Takako, Nagahata, Yoshiko, Matsuura, Tomomi, Hashimoto, Hisayuki, Suzuki, Tomoyuki, Yamashita, Hiromi, Satoh, Yusuke, Egashira, Toru, Seki, Tomohisa, Muraoka, Naoto, Yamakawa, Hiroyuki, Ohgino, Yasuyuki, Tanaka, Tomofumi, Yoichi, Masatoshi, Yuasa, Shinsuke, Murata, Mitsushige, Suematsu, Makoto, Fukuda, Keiichi

“…Heart disease remains a major cause of death despite advances in medical technology. Heart-regenerative therapy that uses pluripotent stem cells (PSCs) is a…”
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Nongenetic method for purifying stem cell-derived cardiomyocytes by Fukuda, Keiichi, Hattori, Fumiyuki, Chen, Hao, Yamashita, Hiromi, Tohyama, Shugo, Satoh, Yu-suke, Yuasa, Shinsuke, Li, Weizhen, Yamakawa, Hiroyuki, Tanaka, Tomofumi, Onitsuka, Takeshi, Shimoji, Kenichiro, Ohno, Yohei, Egashira, Toru, Kaneda, Ruri, Murata, Mitsushige, Hidaka, Kyoko, Morisaki, Takayuki, Sasaki, Erika, Suzuki, Takeshi, Sano, Motoaki, Makino, Shinji, Oikawa, Shinzo

“…Staining with a mitochondrial dye permits high-purity isolation of cardiomyocytes from embryonic and induced pluripotent stem cells of several species, without…”
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In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes by Tanaka, Tomofumi, Tohyama, Shugo, Murata, Mitsushige, Nomura, Fumimasa, Kaneko, Tomoyuki, Chen, Hao, Hattori, Fumiyuki, Egashira, Toru, Seki, Tomohisa, Ohno, Yohei, Koshimizu, Uichi, Yuasa, Shinsuke, Ogawa, Satoshi, Yamanaka, Shinya, Yasuda, Kenji, Fukuda, Keiichi

“…The lethal ventricular arrhythmia Torsade de pointes (TdP) is the most common reason for the withdrawal or restricted use of many cardiovascular and…”
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Disease characterization using LQTS-specific induced pluripotent stem cells by EGASHIRA, Toru, YUASA, Shinsuke, KURODA, Yusuke, YAE, Kojiro, HASHIMOTO, Hisayuki, TANAKA, Tomofumi, HATTORI, Fumiyuki, SATO, Toshiaki, MIYOSHI, Shunichiro, TAKATSUKI, Seiji, MURATA, Mitsushige, KUROKAWA, Junko, SUZUKI, Tomoyuki, FURUKAWA, Tetsushi, MAKITA, Naomasa, AIBA, Takeshi, SHIMIZU, Wataru, HORIE, Minoru, KAMIYA, Kaichiro, KODAMA, Itsuo, OGAWA, Satoshi, FUKUDA, Keiichi, AIZAWA, Yoshiyasu, YAMAKAWA, Hiroyuki, MATSUHASHI, Tomohiro, OHNO, Yohei, TOHYAMA, Shugo, OKATA, Shinichiro, SEKI, Tomohisa

“…Long QT syndrome (LQTS) is an inheritable and life-threatening disease; however, it is often difficult to determine disease characteristics in sporadic cases…”
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Immunoglobulin G4-related Coronary Periarteritis and Luminal Stenosis in a Patient with a History of Autoimmune Pancreatitis by Sakamoto, Aiko, Tanaka, Tomofumi, Hirano, Kenji, Koike, Kazuhiko, Komuro, Issei

“…Immunoglobulin G4 (IgG4)-related disease is a systemic inflammatory disorder that was first described in patients with autoimmune pancreatitis. Although…”
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Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels by Oguri, Gaku, Nakajima, Toshiaki, Yamamoto, Yumiko, Takano, Nami, Tanaka, Tomofumi, Kikuchi, Hironobu, Morita, Toshihiro, Nakamura, Fumitaka, Yamasoba, Tatsuya, Komuro, Issei

“…Cardiac fibroblasts contribute to the pathogenesis of cardiac remodeling. Methylglyoxal (MG) is an endogenous carbonyl compound produced under hyperglycemic…”
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Comparison of the incidence of depression before and after endovascular treatment in patients with lower limb peripheral artery disease by Komatsu, Yasushi, Higashitani, Michiaki, Ueshima, Daisuke, Mizuno, Atsushi, Yamaguchi, Tetsuo, Kodama, Takahide, Tanaka, Tomofumi, Jujo, Kentaro, Murata, Naotaka, Ookoshi, Satoko, Ochiai, Tetsuya, Taya, Yuji, Nemoto, Yoshiko, Abe, Norihiro, Anzai, Hitoshi, Chikamori, Taishiro

“…Depression is a chronic illness that affects mood, physical health, and overall vitality and quality of life. Depression has been associated with an increased…”
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G-CSF Promotes the Proliferation of Developing Cardiomyocytes In Vivo and in Derivation from ESCs and iPSCs by Shimoji, Kenichiro, Yuasa, Shinsuke, Onizuka, Takeshi, Hattori, Fumiyuki, Tanaka, Tomofumi, Hara, Mie, Ohno, Yohei, Chen, Hao, Egasgira, Toru, Seki, Tomohisa, Yae, Kojiro, Koshimizu, Uichi, Ogawa, Satoshi, Fukuda, Keiichi

“…During a screen for humoral factors that promote cardiomyocyte differentiation from embryonic stem cells (ESCs), we found marked elevation of granulocyte…”
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Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells by Fukuda, Keiichi, Yuasa, Shinsuke, Itabashi, Yuji, Koshimizu, Uichi, Tanaka, Tomofumi, Sugimura, Keijiro, Kinoshita, Masayoshi, Hattori, Fumiyuki, Fukami, Shin-ichi, Shimazaki, Takuya, Okano, Hideyuki, Ogawa, Satoshi

“…Embryonic stem (ES) cells are a promising source of cardiomyocytes, but clinical application of ES cells has been hindered by the lack of reliable selective…”
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Proportion of Flat- and Depressed-Type and Laterally Spreading Tumor Among Advanced Colorectal Neoplasia by Kaku, Eisuke, Oda, Yasushi, Murakami, Yoshitaka, Goto, Hideyo, Tanaka, Tomofumi, Hasuda, Kiwamu, Yasunaga, Makoto, Ito, Kiyoharu, Sakurai, Kouichi, Fujimori, Takahiro, Hattori, Masahiro, Sasaki, Yutaka

“…Background & Aims Flat- and depressed-type neoplasias along with laterally spreading tumors (LSTs) have been reported in colorectal neoplasias. We estimated…”
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E-cadherin-coated plates maintain pluripotent ES cells without colony formation by Nagaoka, Masato, Koshimizu, Uichi, Yuasa, Shinsuke, Hattori, Fumiyuki, Chen, Hao, Tanaka, Tomofumi, Okabe, Masaru, Fukuda, Keiichi, Akaike, Toshihiro

“…Embryonic stem (ES) cells cultured on gelatin-coated plates or feeder layers form tight aggregated colonies by the E-cadherin-mediated cell-cell adhesions…”
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Baseline inflammatory status affects the prognostic impact of statins in patients with peripheral arterial disease by Jujo, Kentaro, Ueshima, Daisuke, Abe, Takuro, Shimazaki, Kensuke, Fujimoto, Yo, Tanaka, Tomofumi, Murata, Teppei, Miyazaki, Toru, Matsumoto, Michiaki, Tokuyama, Hideo, Shimura, Tsukasa, Funada, Ryuichi, Murata, Naotaka, Higashitani, Michiaki

“…Statins bring favourable effects on the clinical prognosis of patients with atherosclerotic disease partly through their anti-inflammatory properties. However,…”
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Maternal‐effect gene Ces5/Ooep/Moep19/Floped is essential for oocyte cytoplasmic lattice formation and embryonic development at the maternal‐zygotic stage transition by Tashiro, Fumi, Kanai‐Azuma, Masami, Miyazaki, Satsuki, Kato, Masahiro, Tanaka, Tomofumi, Toyoda, Shuichi, Yamato, Eiji, Kawakami, Hayato, Miyazaki, Tatsushi, Miyazaki, Jun‐Ichi

“…In a search for genes specifically expressed in mouse embryonic stem cells, we identified one we called Ces5. We found that it corresponded to the Ooep gene,…”
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Wnt2 accelerates cardiac myocyte differentiation from ES-cell derived mesodermal cells via non-canonical pathway by Onizuka, Takeshi, Yuasa, Shinsuke, Kusumoto, Dai, Shimoji, Kenichiro, Egashira, Toru, Ohno, Yohei, Kageyama, Toshimi, Tanaka, Tomofumi, Hattori, Fumiyuki, Fujita, Jun, Ieda, Masaki, Kimura, Kensuke, Makino, Shinji, Sano, Motoaki, Kudo, Akira, Fukuda, Keiichi

“…Abstract The efficient induction of cardiomyocyte differentiation from embryonic stem (ES) cells is crucial for cardiac regenerative medicine. Although Wnts…”
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Functional analysis of Tcl1 using Tcl1-deficient mouse embryonic stem cells by Miyazaki, Tatsushi, Miyazaki, Satsuki, Ashida, Masafumi, Tanaka, Tomofumi, Tashiro, Fumi, Miyazaki, Jun-ichi

“…Tcl1 is highly expressed in embryonic stem (ES) cells, but its expression rapidly decreases following differentiation. To assess Tcl1's roles in ES cells, we…”
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Impact of the distance from the stent edge to the residual plaque on edge restenosis following everolimus-eluting stent implantation by Takahashi, Masao, Miyazaki, Susumu, Myojo, Masahiro, Sawaki, Daigo, Iwata, Hiroshi, Kiyosue, Arihiro, Higashikuni, Yasutomi, Tanaka, Tomofumi, Fujita, Daishi, Ando, Jiro, Fujita, Hideo, Hirata, Yasunobu, Komuro, Issei

“…This study aimed to assess the relation between stent edge restenosis (SER) and the distance from the stent edge to the residual plaque using quantitative…”
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Roles of transient receptor potential canonical (TRPC) channels and reverse-mode Na+ /Ca2+ exchanger on cell proliferation in human cardiac fibroblasts: Effects of transforming growth factor β1 by Ikeda, Kenichi, Nakajima, Toshiaki, Yamamoto, Yumiko, Takano, Nami, Tanaka, Tomofumi, Kikuchi, Hironobu, Oguri, Gaku, Morita, Toshihiro, Nakamura, Fumitaka, Komuro, Issei

“…Abstract Expression of transient receptor potential canonical channels (TRPC) and the effects of transforming growth factor-β1 (TGF-β1) on Ca2+ signals and…”
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Proportion of De Novo Cancers Among Colorectal Cancers in Japan by Goto, Hideyo, Oda, Yasushi, Murakami, Yoshitaka, Tanaka, Tomofumi, Hasuda, Kiwamu, Goto, Sayoko, Sasaki, Yutaka, Sakisaka, Shotaro, Hattori, Masahiro

“…Background & Aims: Adenomatous polyps are main precursors of colorectal cancers (CRCs). In Japan, de novo cancers, which do not arise from preexisting…”
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Effects of Serum Amyloid A and Lysophosphatidylcholine on Intracellular Calcium Concentration in Human Coronary Artery Smooth Muscle Cells by Tanaka, Tomofumi, Ikeda, Kenichi, Yamamoto, Yumiko, Iida, Haruko, Kikuchi, Hironobu, Morita, Toshihiro, Yamasoba, Tatsuya, Nagai, Ryozo, Nakajima, Toshiaki

“…Serum amyloid A (SAA), an acute-phase protein, and lysophosphatidylcholine (LPC), an oxidized LDL component, contribute to the physiological processes of…”
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Distinct iPS Cells Show Different Cardiac Differentiation Efficiency by Hashimoto, Hisayuki, Seki, Tomohisa, Egashira, Toru, Yuasa, Shinsuke, Ohno, Yohei, Tohyama, Shugo, Saito, Yuki, Kunitomi, Akira, Shimoji, Kenichiro, Onizuka, Takeshi, Kageyama, Toshimi, Yae, Kojiro, Tanaka, Tomofumi, Kaneda, Ruri, Hattori, Fumiyuki, Murata, Mitsushige, Kimura, Kensuke, Fukuda, Keiichi

“…Patient-specific induced pluripotent stem (iPS) cells can be generated by introducing transcription factors that are highly expressed in embryonic stem (ES)…”
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