Search Results - "Tanaka, Tetsuya S"
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Soft substrates promote homogeneous self-renewal of embryonic stem cells via downregulating cell-matrix tractions
Published in PloS one (13-12-2010)“…Maintaining undifferentiated mouse embryonic stem cell (mESC) culture has been a major challenge as mESCs cultured in Leukemia Inhibitory Factor (LIF)…”
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Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells
Published in Nature materials (01-01-2010)“…Growing evidence suggests that physical microenvironments and mechanical stresses, in addition to soluble factors, help direct mesenchymal-stem-cell fate…”
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Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions
Published in The Journal of cell biology (01-11-2010)“…Human embryonic stem cells (ESCs [hESCs]) proliferate as colonies wherein individual cells are strongly adhered to one another. This architecture is linked to…”
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SMARCAD1 Contributes to the Regulation of Naive Pluripotency by Interacting with Histone Citrullination
Published in Cell reports (Cambridge) (28-03-2017)“…Histone citrullination regulates diverse cellular processes. Here, we report that SMARCAD1 preferentially associates with H3 arginine 26 citrullination…”
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Functional analysis of CTRP3/cartducin in Meckel’s cartilage and developing condylar cartilage in the fetal mouse mandible
Published in Journal of anatomy (01-05-2011)“…CTRP3/cartducin, a novel C1q family protein, is expressed in proliferating chondrocytes in the growth plate and has an important role in regulating the growth…”
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Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages
Published in Blood (15-09-2005)“…Interferon regulatory factor-8 (IRF-8)/interferon consensus sequence–binding protein (ICSBP) is a transcription factor that controls myeloid-cell development…”
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Transcriptional heterogeneity in mouse embryonic stem cells
Published in Reproduction fertility and development (2009)“…The embryonic stem (ES) cell is a stem cell derived from early embryos that can indefinitely repeat self-renewing cell division cycles as an undifferentiated…”
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Short-term serum-free culture reveals that inhibition of Gsk3β induces the tumor-like growth of mouse embryonic stem cells
Published in PloS one (2011)“…Here, we present evidence that the tumor-like growth of mouse embryonic stem cells (mESCs) is suppressed by short-term serum-free culture, which is reversed by…”
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Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stemcells
Published in Nature materials (01-01-2010)“…Growing evidence suggests that physical microenvironments and mechanical stresses, in addition to soluble factors, help direct mesenchymal-stem-cell fate…”
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Genome-Wide Expression Profiling of Mid-Gestation Placenta and Embryo Using a 15,000 Mouse Developmental cDNA Microarray
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-2000)“…cDNA microarray technology has been increasingly used to monitor global gene expression patterns in various tissues and cell types. However, applications to…”
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Transcriptome analysis of mouse stem cells and early embryos
Published in PLoS biology (01-12-2003)“…Understanding and harnessing cellular potency are fundamental in biology and are also critical to the future therapeutic use of stem cells. Transcriptome…”
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Generation of organized germ layers from a single mouse embryonic stem cell
Published in Nature communications (30-05-2014)“…Mammalian inner cell mass cells undergo lineage-specific differentiation into germ layers of endoderm, mesoderm and ectoderm during gastrulation. It has been a…”
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Maintenance, Transgene Delivery, and Pluripotency Measurement of Mouse Embryonic Stem Cells
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2016)“…This chapter describes standard techniques to (1) maintain mouse embryonic stem cell culture, (2) deliver transgenes into mouse embryonic stem cells mediated…”
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Verification and initial annotation of the NIA mouse 15K cDNA clone set
Published in Nature genetics (01-05-2001)Get full text
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A global view of gene expression in the preimplantation mouse embryo: morula versus blastocyst
Published in European journal of obstetrics & gynecology and reproductive biology (01-07-2004)“…As a first step to understand preimplantation development, we performed global gene-expression profiling of morula and blastocyst using the NIA 15k mouse cDNA…”
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Journal Article Conference Proceeding -
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Embryonic Stem Cells Do Not Stiffen on Rigid Substrates
Published in Biophysical journal (21-07-2010)“…It has been previously established that living cells, including mesenchymal stem cells, stiffen in response to elevation of substrate stiffness. This…”
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Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA‐binding protein with broad RNA targets
Published in Development, growth & differentiation (01-08-2006)“…In our earlier attempt to identify genes involved in the maintenance of cellular pluripotency, we found that KH‐domain protein Embryonal stem cell‐specific…”
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Spatio‐temporal expression of Xenopus vasa homolog, XVLG1, in oocytes and embryos: The presence of XVLG1 RNA in somatic cells as well as germline cells
Published in Development, growth & differentiation (01-04-2000)“…The expression of Xenopus vasa homolog or XVLG1 was examined in oocytes and embryos by whole‐mount in situ hybridization and reverse transcription–polymerase…”
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Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells
Published in Genomics (San Diego, Calif.) (01-11-2013)“…We examined the transcriptional activity of Oct3/4 (Pou5f1) in mouse embryonic stem cells (mESCs) maintained under standard culture conditions to gain a better…”
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Force via integrins but not E-cadherin decreases Oct3/4 expression in embryonic stem cells
Published in Biochemical and biophysical research communications (18-11-2011)“…► Force via integrins or cadherins induces similar cell stiffening responses. ► Force via integrins but not cadherins induces cell spreading. ► Force via…”
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