Search Results - "Tanaka, Tetsuya S"

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    Soft substrates promote homogeneous self-renewal of embryonic stem cells via downregulating cell-matrix tractions by Chowdhury, Farhan, Li, Yanzhen, Poh, Yeh-Chuin, Yokohama-Tamaki, Tamaki, Wang, Ning, Tanaka, Tetsuya S

    Published in PloS one (13-12-2010)
    “…Maintaining undifferentiated mouse embryonic stem cell (mESC) culture has been a major challenge as mESCs cultured in Leukemia Inhibitory Factor (LIF)…”
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    Journal Article
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    Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells by Wang, Ning, Chowdhury, Farhan, Na, Sungsoo, Li, Dong, Poh, Yeh-Chuin, Tanaka, Tetsuya S, Wang, Fei

    Published in Nature materials (01-01-2010)
    “…Growing evidence suggests that physical microenvironments and mechanical stresses, in addition to soluble factors, help direct mesenchymal-stem-cell fate…”
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    Journal Article
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    Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions by Li, Dong, Zhou, Jiaxi, Wang, Lu, Shin, Myung Eun, Su, Pei, Lei, Xiaohua, Kuang, Haibin, Guo, Weixiang, Yang, Hong, Cheng, Linzhao, Tanaka, Tetsuya S, Leckband, Deborah E, Reynolds, Albert B, Duan, Enkui, Wang, Fei

    Published in The Journal of cell biology (01-11-2010)
    “…Human embryonic stem cells (ESCs [hESCs]) proliferate as colonies wherein individual cells are strongly adhered to one another. This architecture is linked to…”
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    Journal Article
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    Functional analysis of CTRP3/cartducin in Meckel’s cartilage and developing condylar cartilage in the fetal mouse mandible by Yokohama‐Tamaki, Tamaki, Maeda, Takashi, Tanaka, Tetsuya S., Shibata, Shunichi

    Published in Journal of anatomy (01-05-2011)
    “…CTRP3/cartducin, a novel C1q family protein, is expressed in proliferating chondrocytes in the growth plate and has an important role in regulating the growth…”
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    Journal Article
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    Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages by Tamura, Tomohiko, Thotakura, Pratima, Tanaka, Tetsuya S., Ko, Minoru S.H., Ozato, Keiko

    Published in Blood (15-09-2005)
    “…Interferon regulatory factor-8 (IRF-8)/interferon consensus sequence–binding protein (ICSBP) is a transcription factor that controls myeloid-cell development…”
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    Journal Article
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    Transcriptional heterogeneity in mouse embryonic stem cells by Tanaka, Tetsuya S

    “…The embryonic stem (ES) cell is a stem cell derived from early embryos that can indefinitely repeat self-renewing cell division cycles as an undifferentiated…”
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    Journal Article
  8. 8

    Short-term serum-free culture reveals that inhibition of Gsk3β induces the tumor-like growth of mouse embryonic stem cells by Li, Yanzhen, Yokohama-Tamaki, Tamaki, Tanaka, Tetsuya S

    Published in PloS one (2011)
    “…Here, we present evidence that the tumor-like growth of mouse embryonic stem cells (mESCs) is suppressed by short-term serum-free culture, which is reversed by…”
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    Journal Article
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    Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stemcells by Chowdhury, Farhan, Na, Sungsoo, Li, Dong, Poh, Yeh-Chuin, Tanaka, Tetsuya S, Wang, Fei, Wang, Ning

    Published in Nature materials (01-01-2010)
    “…Growing evidence suggests that physical microenvironments and mechanical stresses, in addition to soluble factors, help direct mesenchymal-stem-cell fate…”
    Get full text
    Journal Article
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    Generation of organized germ layers from a single mouse embryonic stem cell by Poh, Yeh-Chuin, Chen, Junwei, Hong, Ying, Yi, Haiying, Zhang, Shuang, Chen, Junjian, Wu, Douglas C., Wang, Lili, Jia, Qiong, Singh, Rishi, Yao, Wenting, Tan, Youhua, Tajik, Arash, Tanaka, Tetsuya S., Wang, Ning

    Published in Nature communications (30-05-2014)
    “…Mammalian inner cell mass cells undergo lineage-specific differentiation into germ layers of endoderm, mesoderm and ectoderm during gastrulation. It has been a…”
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    Journal Article
  13. 13

    Maintenance, Transgene Delivery, and Pluripotency Measurement of Mouse Embryonic Stem Cells by Tanaka, Tetsuya S

    “…This chapter describes standard techniques to (1) maintain mouse embryonic stem cell culture, (2) deliver transgenes into mouse embryonic stem cells mediated…”
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    Journal Article
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    A global view of gene expression in the preimplantation mouse embryo: morula versus blastocyst by Tanaka, Tetsuya S, Ko, Minoru S.H

    “…As a first step to understand preimplantation development, we performed global gene-expression profiling of morula and blastocyst using the NIA 15k mouse cDNA…”
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    Journal Article Conference Proceeding
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    Embryonic Stem Cells Do Not Stiffen on Rigid Substrates by Poh, Yeh-Chuin, Chowdhury, Farhan, Tanaka, Tetsuya S., Wang, Ning

    Published in Biophysical journal (21-07-2010)
    “…It has been previously established that living cells, including mesenchymal stem cells, stiffen in response to elevation of substrate stiffness. This…”
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    Journal Article
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    Spatio‐temporal expression of Xenopus vasa homolog, XVLG1, in oocytes and embryos: The presence of XVLG1 RNA in somatic cells as well as germline cells by Ikenishi, Kohji, Tanaka, Tetsuya S

    Published in Development, growth & differentiation (01-04-2000)
    “…The expression of Xenopus vasa homolog or XVLG1 was examined in oocytes and embryos by whole‐mount in situ hybridization and reverse transcription–polymerase…”
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    Journal Article
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    Gene expression profiling reveals the heterogeneous transcriptional activity of Oct3/4 and its possible interaction with Gli2 in mouse embryonic stem cells by Li, Yanzhen, Drnevich, Jenny, Akraiko, Tatiana, Band, Mark, Li, Dong, Wang, Fei, Matoba, Ryo, Tanaka, Tetsuya S.

    Published in Genomics (San Diego, Calif.) (01-11-2013)
    “…We examined the transcriptional activity of Oct3/4 (Pou5f1) in mouse embryonic stem cells (mESCs) maintained under standard culture conditions to gain a better…”
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    Journal Article
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    Force via integrins but not E-cadherin decreases Oct3/4 expression in embryonic stem cells by Uda, Yuhei, Poh, Yeh-Chuin, Chowdhury, Farhan, Wu, Douglas C., Tanaka, Tetsuya S., Sato, Masaaki, Wang, Ning

    “…► Force via integrins or cadherins induces similar cell stiffening responses. ► Force via integrins but not cadherins induces cell spreading. ► Force via…”
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    Journal Article