Search Results - "Tanaka, Kaori"
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Superconductive sodalite-like clathrate calcium hydride at high pressures
Published in Proceedings of the National Academy of Sciences - PNAS (24-04-2012)“…Hydrogen-rich compounds hold promise as high-temperature superconductors under high pressures. Recent theoretical hydride structures on achieving high-pressure…”
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2
Oral Intake Difficulty and Aspiration Pneumonia Assessment Using High‐Resolution Manometry
Published in The Laryngoscope (01-05-2024)“…Objective The sequential generation of swallowing pressure (SP) from the nasopharynx to the proximal esophagus is important for the bolus to pass from the oral…”
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AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation
Published in Cell (23-10-2014)“…The recognition of modified histones by “reader” proteins constitutes a key mechanism regulating gene expression in the chromatin context. Compared with the…”
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Quartz-Seq2: a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads
Published in Genome Biology (09-03-2018)“…High-throughput single-cell RNA-seq methods assign limited unique molecular identifier (UMI) counts as gene expression values to single cells from shallow…”
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Cytotoxic Effects of Water-Soluble Extracts of Coarse and Fine Atmospheric Particulate Matter on Mast Cell Lines
Published in Biological & pharmaceutical bulletin (01-01-2021)“…Fine particulate matter (PM2.5) pollution causes serious health disorders, because PM2.5 becomes deposited in the tracheobronchial and alveoli regions. In the…”
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6
Aldehyde dehydrogenase 1A1 in stem cells and cancer
Published in Oncotarget (08-03-2016)Get full text
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Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis
Published in Genome research (01-02-2018)“…Noncoding transcription is a defining feature of active enhancers, linking transcription factor (TF) binding to the molecular mechanisms controlling gene…”
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Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation
Published in Proceedings of the National Academy of Sciences - PNAS (22-10-2013)“…Estrogen receptor alpha (ERα) is a ligand-activated transcription factor. Upon estrogen stimulation, ERα recruits a number of coregulators, including both…”
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Author Correction: Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis
Published in Nature communications (17-10-2023)Get full text
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Single-cell transcriptomics uncovers EGFR signaling-mediated gastric progenitor cell differentiation in stomach homeostasis
Published in Nature communications (29-06-2023)“…Defects in gastric progenitor cell differentiation are associated with various gastric disorders, including atrophic gastritis, intestinal metaplasia, and…”
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11
Synthesis, Characterization, and Antileukemic Properties of Naphthoquinone Derivatives of Lawsone
Published in ChemMedChem (01-08-2015)“…Naphthoquinones are considered privileged structures for anticancer drug molecules. The Heck reaction of 2‐hydroxy‐1,4‐naphthoquinone (lawsone) with…”
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In vitro activities and spectrum of lascufloxacin(KRP-AM1977)against anaerobes
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-08-2021)“…The in vitro antibacterial spectra and activities of five antimicrobial agents, including lascufloxacin (LSFX) and two quinolones, were investigated against 69…”
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High-depth spatial transcriptome analysis by photo-isolation chemistry
Published in Nature communications (20-07-2021)“…In multicellular organisms, expression profiling in spatially defined regions is crucial to elucidate cell interactions and functions. Here, we establish a…”
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CTCF binding landscape in jawless fish with reference to Hox cluster evolution
Published in Scientific reports (10-07-2017)“…The nuclear protein CCCTC-binding factor (CTCF) contributes as an insulator to chromatin organization in animal genomes. Currently, our knowledge of its…”
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Plasma cell differentiation is regulated by the expression of histone variant H3.3
Published in Nature communications (20-06-2024)“…The differentiation of B cells into plasma cells is associated with substantial transcriptional and epigenetic remodeling. H3.3 histone variant marks active…”
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Precise immunofluorescence canceling for highly multiplexed imaging to capture specific cell states
Published in Nature communications (08-05-2024)“…Cell states are regulated by the response of signaling pathways to receptor ligand-binding and intercellular interactions. High-resolution imaging has been…”
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First Case of Necrotizing Fasciitis and Septicemia Caused by Pigmentibacter ruber
Published in Japanese Journal of Infectious Diseases (31-07-2024)“…We report the first case of necrotizing fasciitis caused by Pigmentibacter ruber. The isolated strain could not be identified by biochemical characterization…”
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DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV
Published in Proceedings of the National Academy of Sciences - PNAS (14-05-2013)“…DNA methylation is an important epigenetic mark in many eukaryotic organisms. De novo DNA methylation in plants can be achieved by the RNA-directed DNA…”
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Synthesis and Cytotoxicity on Human Leukemia Cells of Furonaphthoquinones Isolated from Tabebuia Plants
Published in Chemical & pharmaceutical bulletin (01-06-2013)“…Furonaphthoquinones are promising skeletons for anticancer drug molecules. In particular, methoxylated furonaphthoquinones are characteristic constituents of…”
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A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model
Published in Molecular psychiatry (01-08-2022)“…Immune dysregulation plays a key role in the pathogenesis of autism. Changes occurring at the systemic level, from brain inflammation to disturbed…”
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