Search Results - "Tan Hock Siew"

Putative Pathogenic Genes of Leptospira interrogans and Leptospira weilii Isolated from Patients with Acute Febrile Illness by Safiee, Amira Wahida Mohamad, Mohd Ali, Mohammad Ridhuan, Zoqratt, Muhammad Zarul Hanifah Md, Siew, Tan Hock, Chuan, Chua Wei, Huey, Lee Lih, Fauzi, Mohd Hashairi, Besari, Alwi Muhd, Yean Yean, Chan, Ismail, Nabilah

“…Leptospirosis is an important worldwide tropical disease caused by pathogenic Leptospira spp. The determination of virulence genes is important, as it…”
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Mock grant application roleplay as an alternative to lab‐based activities in molecular biology by Tan, Hock Siew

“…Many universities resort to online teaching due to COVID‐19 pandemic. It is a challenging endeavor, especially in Molecular Biology courses that require lab…”
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Use of the waxworm Galleria mellonella larvae as an infection model to study Acinetobacter baumannii by Ten, Kah Ern, Muzahid, Nazmul Hasan, Rahman, Sadequr, Tan, Hock Siew

“…Galleria mellonella larvae have been increasingly used in research, including microbial infection studies. They act as suitable preliminary infection models to…”
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Unveiling the functional epitopes of cobra venom cytotoxin by immunoinformatics and epitope-omic analyses by Hiu, Jia Jin, Fung, Jared Kah Yin, Tan, Hock Siew, Yap, Michelle Khai Khun

“…Approximate 70% of cobra venom is composed of cytotoxin (CTX), which is responsible for the dermonecrotic symptoms of cobra envenomation. However, CTX is…”
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Selecting antibacterial aptamers against the BamA protein in Pseudomonas aeruginosa by incorporating genetic algorithm to optimise computational screening method by Selvam, Rupany, Lim, Ian Han Yan, Lewis, Jovita Catherine, Lim, Chern Hong, Yap, Michelle Khai Khun, Tan, Hock Siew

“…Antibiotic resistance is one of the biggest threats to global health resulting in an increasing number of people suffering from severe illnesses or dying due…”
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Authentic research experience through mock grant application roleplay by Tan, Hock Siew, Lim, Caryn

“…Many universities resort to online teaching due to the COVID-19 pandemic. It is a challenging endeavour, especially in Biology courses that require lab access…”
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Genomic and phenotypic characterization of Acinetobacter colistiniresistens isolated from the feces of a healthy member of the community by Muzahid, Nazmul Hasan, Md Zoqratt, Muhammad Zarul Hanifah, Ten, Kah Ern, Hussain, Md Hamed, Su, Tin Tin, Ayub, Qasim, Tan, Hock Siew, Rahman, Sadequr

“…Acinetobacter species are widely known opportunistic pathogens causing severe community and healthcare-associated infections. One such emerging pathogen,…”
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A small RNA decreases the sensitivity of Shigella sonnei to norfloxacin by Gan, I-Ning, Tan, Hock Siew

“…Shigella is a human pathogen that causes shigellosis, an acute invasive intestinal infection. Recent studies in the model bacterium Escherichia coli (E. coli)…”
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Differential RNA-seq (dRNA-seq) for annotation of transcriptional start sites and small RNAs in Helicobacter pylori by Bischler, Thorsten, Tan, Hock Siew, Nieselt, Kay, Sharma, Cynthia M.

“…•A differential RNA-seq (dRNA-seq) approach for primary transcriptome analysis.•dRNA-seq analysis of the gastric pathogen Helicobacter pylori as a model…”
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Characterization of multidrug-resistant Acinetobacter baumannii strain ATCC BAA1605 using whole-genome sequencing by Ten, Kah Ern, Md Zoqratt, Muhammad Zarul Hanifah, Ayub, Qasim, Tan, Hock Siew

“…The nosocomial pathogen, Acinetobacter baumannii, has acquired clinical significance due to its ability to persist in hospital settings and survive antibiotic…”
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Anti-biofilm potential of red pitahaya betacyanins against Streptococcus mutans, Actinomyces viscosus and Aggregatibacter actinomycetemcomitans by Sathiaseelan, Allimalar, Song, Keang Peng, Tan, Hock Siew, Choo, Wee Sim

“…This study investigated the antibiofilm effects of betacyanin fraction (BF) from red pitahaya against Streptococcus mutans, Actinomyces viscosus, and…”
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Adaptation of a fluoroquinolone-sensitive Shigella sonnei to norfloxacin exposure by Wong, Bao Chi, Law, Soffi Kei Kei, Md Zoqratt, Muhammad Zarul Hanifah, Ayub, Qasim, Tan, Hock Siew

“…causes shigellosis that requires antibiotic treatment in severe cases. Sublethal antibiotic concentrations can promote resistance, but their effect on…”
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Acinetobacter baumannii subunit vaccines: recent progress and challenges by Lau, Yi Teng, Tan, Hock Siew

“…is a Gram-negative, opportunistic pathogen that causes nosocomial infection with a high mortality rate in immunocompromised individuals. With the frequent…”
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The role of quorum sensing, biofilm formation, and iron acquisition as key virulence mechanisms in Acinetobacter baumannii and the corresponding anti-virulence strategies by Law, Soffi Kei Kei, Tan, Hock Siew

“…Acinetobacter baumannii is a nosocomial pathogen responsible for several serious infections, including pneumonia, sepsis, and meningitis. The propensity of…”
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Epitope-Omics directed discovery of Apt6: Neutralisation effects against cobra venom by Jin, Hiu Jia, Siew, Tan Hock, Khai Khun, Yap Michelle

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Investigating Riboswitches in Enterobacteria as Potential Antimicrobial Drug Targets by Shahid, Umama, Tan, Hock Siew

“…Introduction: Drug overuse and evolution of microorganisms has made antimicrobial resistance one of the most critical threats currently. Pathogens, like the…”
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Unveiling the Virulence of Pathogenic Community-Acquired A. baumannii using Galleria mellonella as Infection Model by Ten, Kah Ern, Tan, Hock Siew

“…Introduction: Acinetobacter baumannii (A. baumannii), the top priority pathogen classified by the World Health Organisation, has caused serious impacts in the…”
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Adaptation of a Fluoroquinolone-Sensitive Shigella sonnei to Sub-lethal Concentration of Norfloxacin through Stringent Response and Small Non-Coding RNAs by Law, Soffi Kei Kei, Tan, Hock Siew

“…Introduction: Shigella sonnei is the predominant species that causes shigellosis, a form of diarrheal infection associated with high mortality rates. This…”
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Determination of Shigella sonnei Virulence using Caenorhabditis elegans Infection Model by Wong, Bao Chi, Tan, Hock Siew

“…Introduction: Shigella is the second leading cause of diarrhoeal mortality, leading to more than 60 thousand deaths in children younger than five years. In…”
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RNA-cleaving DNAzymes as a diagnostic and therapeutic agent against antimicrobial resistant bacteria by Wong, Bao Chi, Abu Bakar, Juwaini, Dhanoa, Amreeta, Tan, Hock Siew

“…The development of nucleic-acid-based antimicrobials such as RNA-cleaving DNAzyme (RCD), a short catalytically active nucleic acid, is a promising alternative…”
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