Search Results - "Tan, Yuying"
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Metabolic reprogramming from glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells
Published in Nature communications (05-08-2022)“…Increased glycolysis is considered as a hallmark of cancer. Yet, cancer cell metabolic reprograming during therapeutic resistance development is under-studied…”
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The Role of Osteopontin in Tumor Progression Through Tumor-Associated Macrophages
Published in Frontiers in oncology (08-07-2022)“…Osteopontin (OPN) is a multifunctional phosphorylated protein. It is widely involved in solid tumor progression, such as intensification of macrophage…”
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Lactylation-Related Gene Signature Effectively Predicts Prognosis and Treatment Responsiveness in Hepatocellular Carcinoma
Published in Pharmaceuticals (Basel, Switzerland) (25-04-2023)“…Hepatocellular carcinoma (HCC) is a malignant tumor associated with high morbidity and mortality. Therefore, it is of great importance to develop effective…”
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Nanosecond-resolution photothermal dynamic imaging via MHZ digitization and match filtering
Published in Nature communications (07-12-2021)“…Photothermal microscopy has enabled highly sensitive label-free imaging of absorbers, from metallic nanoparticles to chemical bonds. Photothermal signals are…”
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Identification of a pyroptosis-related lncRNA risk model for predicting prognosis and immune response in colon adenocarcinoma
Published in World journal of surgical oncology (12-04-2022)“…Colon adenocarcinoma (COAD) is one of the most common malignant tumors and is diagnosed at an advanced stage with a poor prognosis worldwide. Pyroptosis is…”
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Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer
Published in Cancer letters (28-09-2018)“…Recombinant methioninase (rMETase) was previously administered as an injectable drug to target methionine dependence of cancer. Recently, we observed that…”
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Knockdown of TRIM44 Inhibits the Proliferation and Invasion in Prostate Cancer Cells
Published in Oncology research (21-09-2017)“…Tripartite motif 44 (TRIM44), a member of the TRIM protein family, has been shown to play a role in tumor development and progression. However, the potential…”
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Characterization of Aroma Volatiles in Xilin Fire Ginger Oils by HS-SPME-GC-MS
Published in International journal of food properties (31-12-2022)“…Ginger is widely used as either a food product or a herbal medicine around the globe. In the current study, we used headspace solid-phase microextraction and…”
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High expression level of CXCL1/GROα is linked to advanced stage and worse survival in uterine cervical cancer and facilitates tumor cell malignant processes
Published in BMC cancer (28-06-2022)“…Abstract Background CXCL1 belongs to a member of the ELR + CXC chemokine subgroups that also known as GRO-alpha. It has been recognized that several types of…”
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Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model
Published in Biochemical and biophysical research communications (26-02-2020)“…Cancer cells are methionine (MET) and methylation addicted and are highly sensitive to MET restriction. The present study determined the efficacy of…”
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Multiplex Stimulated Raman Scattering Imaging Cytometry Reveals Lipid-Rich Protrusions in Cancer Cells under Stress Condition
Published in iScience (27-03-2020)“…In situ measurement of cellular metabolites is still a challenge in biology. Conventional methods, such as mass spectrometry or fluorescence microscopy, would…”
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Advances in the potential roles of Cullin-RING ligases in regulating autoimmune diseases
Published in Frontiers in immunology (17-03-2023)“…Cullin-RING ligases (CRLs) are the largest class of E3 ubiquitin ligases regulating the stability and subsequent activity of a large number of important…”
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Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer
Published in Cell death discovery (27-07-2022)“…Pyroptosis, a type of inflammatory programmed cell death, is triggered by caspase cleavage of gasdermin family proteins. Based on accumulating evidence,…”
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The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model
Published in Cancer chemotherapy and pharmacology (01-02-2020)“…Purpose Cancers are methionine (MET) and methylation addicted, causing them to be highly sensitive to MET restriction. The present study determined the…”
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Aspirin Use and Mortality in Women With Ovarian Cancer: A Meta-Analysis
Published in Frontiers in oncology (01-02-2021)“…Aspirin use has been suggested to reduce the incidence of ovarian cancer (OC) in women. However, previous studies regarding the association between aspirin use…”
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Broad Selective Efficacy of Recombinant Methioninase and Polyethylene Glycol-modified Recombinant Methioninase on Cancer Cells In Vitro
Published in Anticancer research (01-04-2010)“…Elevated dependence on methionine of cancer cells is a cancer-specific metabolic defect. Recombinant L-methionine alpha,gamma-lyase (rMETase), an L-methionine…”
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Neuropeptide Substance P Enhances Skin Wound Healing In Vitro and In Vivo under Hypoxia
Published in Biomedicines (22-02-2021)“…Pressure ulcers (PUs) or sores are a secondary complication of diabetic neuropathy and traumatic spinal cord injury (SCI). PUs tend to occur in soft tissues…”
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Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
Published in Oncotarget (30-05-2017)“…Methionine dependence is due to the overuse of methionine for aberrant transmethylation reactions in cancer. Methionine dependence may be the only general…”
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Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review
Published in Cells (Basel, Switzerland) (02-05-2019)“…An excessive requirement for methionine (MET), termed MET dependence, appears to be a general metabolic defect in cancer and has been shown to be a very…”
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Nocardia farcinica infection presenting as a solitary bronchial neoplasm in an immunocompetent adult: a case report
Published in Frontiers in medicine (10-01-2024)“…Nocardia species are gram-positive, acid-fast, saprophytic, aerobic bacilli, predominantly resulting in opportunistic infections in immunocompromised…”
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