Search Results - "Tan, Yow Yong"

ApoE maintains neuronal integrity via microRNA and H3K27me3-mediated repression by Tan, Jiazi, Tan, Yow-Yong, Ngian, Zhen-Kai, Chong, Suet-Yen, Rao, Vinay Kumar, Wang, Jiong-Wei, Zeng, Xianmin, Ong, Chin-Tong

“…ApoE regulates neurogenesis, although how it influences genetic programs remains elusive. Cortical neurons induced from isogenic control and ApoE−/− human…”
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Prototype Foamy Virus Integrase Displays Unique Biochemical Activities among Retroviral Integrases by Rabe, Anthony J, Tan, Yow Yong, Larue, Ross C, Yoder, Kristine E

“…Integrases of different retroviruses assemble as functional complexes with varying multimers of the protein. Retroviral integrases require a divalent metal…”
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Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties by Ngian, Zhen-Kai, Tan, Yow-Yong, Choo, Ching-Thong, Lin, Wei-Qi, Leow, Chao-Yong, Mah, Shan-Jie, Lai, Mitchell Kim-Peng, Chen, Christopher Li-Hsian, Ong, Chin-Tong

“…Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β plaques and Tau tangles in brain tissues. Recent studies indicate that aberrant…”
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Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency by Kotlar, Randi M., Jones, Nathan D., Senavirathne, Gayan, Gardner, Anne M., Messer, Ryan K., Tan, Yow Yong, Rabe, Anthony J., Fishel, Richard, Yoder, Kristine E.

“…Retroviral integrases must navigate host DNA packaged as chromatin during integration of the viral genome. Prototype foamy virus (PFV) integrase (IN) forms a…”
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