Search Results - "Tan, Ya"
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1
Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells
Published in Nature communications (23-04-2021)“…Arginine plays diverse roles in cellular physiology. As a semi-essential amino acid, arginine deprivation has been used to target cancers with arginine…”
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2
Autophagy and its implication in human oral diseases
Published in Autophagy (01-02-2017)“…Macroautophagy/autophagy is a conserved lysosomal degradation process essential for cell physiology and human health. By regulating apoptosis, inflammation,…”
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3
T cell‐derived exosomes containing cytokines induced keratinocytes apoptosis in oral lichen planus
Published in Oral diseases (01-04-2022)“…Objective Oral lichen planus (OLP) is a T cell‐mediated inflammatory disease with uncertain etiology. Exosomes are cell‐derived vesicles containing biological…”
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4
Short-Chain Fatty Acids and Their Association with Signalling Pathways in Inflammation, Glucose and Lipid Metabolism
Published in International journal of molecular sciences (02-09-2020)“…Short-chain fatty acids (SCFAs), particularly acetate, propionate and butyrate, are mainly produced by anaerobic fermentation of gut microbes. SCFAs play an…”
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5
Melatonin: a potential therapeutic approach for the management of primary Sjögren’s syndrome
Published in Immunologic research (01-06-2023)“…Primary Sjögren’s syndrome (pSS) is an autoimmune disease that primarily affects the exocrine glands and is mainly characterized by sicca symptoms of the eyes…”
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6
Hepatitis B virus infection and the risk of hepatocellular carcinoma
Published in World journal of gastroenterology : WJG (28-11-2011)“…Epidemiological studies have provided overwhelming evidence for a causal role of chronic hepatitis B virus(HBV) infection in the development of hepatocellular…”
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7
T cell–derived exosomes induced macrophage inflammatory protein‐1α/β drive the trafficking of CD8+ T cells in oral lichen planus
Published in Journal of cellular and molecular medicine (01-12-2020)“…Oral lichen planus (OLP) is a T cell–mediated chronic inflammatory disease with uncertain aetiology. Exosomes are nanosized particles with biological…”
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8
RNA 3D Structure Prediction: Progress and Perspective
Published in Molecules (Basel, Switzerland) (20-07-2023)“…Ribonucleic acid (RNA) molecules play vital roles in numerous important biological functions such as catalysis and gene regulation. The functions of RNAs are…”
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9
A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-amyloid
Published in Chemical communications (Cambridge, England) (26-02-2019)“…A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid…”
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10
Single-cell RNA sequencing reveals B cell–related molecular biomarkers for Alzheimer’s disease
Published in Experimental & molecular medicine (01-12-2021)“…In recent years, biomarkers have been integrated into the diagnostic process and have become increasingly indispensable for obtaining knowledge of the…”
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11
γδ T cells in oral diseases
Published in Inflammation research (01-05-2024)“…Objective γδ T cells are a distinct subset of unconventional T cells, which link innate and adaptive immunity by secreting cytokines and interacting with other…”
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12
Cell Heterogeneity and Variability in Peripheral Nerve after Injury
Published in International journal of molecular sciences (01-03-2024)“…With the development of single-cell sequencing technology, the cellular composition of more and more tissues is being elucidated. As the whole nervous system…”
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13
3D porous poly(ε-caprolactone)/58S bioactive glass–sodium alginate/gelatin hybrid scaffolds prepared by a modified melt molding method for bone tissue engineering
Published in Materials & design (15-12-2018)“…Natural-synthetic hybrid scaffold has attracted great interest due to its synergistic effect on load-bearing bone reconstruction. Herein, sodium alginate…”
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14
FebRNA: An automated fragment-ensemble-based model for building RNA 3D structures
Published in Biophysical journal (20-09-2022)“…Knowledge of RNA three-dimensional (3D) structures is critical to understanding the important biological functions of RNAs. Although various structure…”
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15
rsRNASP: A residue-separation-based statistical potential for RNA 3D structure evaluation
Published in Biophysical journal (04-01-2022)“…Knowledge-based statistical potentials have been shown to be rather effective in protein 3-dimensional (3D) structure evaluation and prediction. Recently,…”
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16
Ab initio predictions for 3D structure and stability of single- and double-stranded DNAs in ion solutions
Published in PLoS computational biology (19-10-2022)“…The three-dimensional (3D) structure and stability of DNA are essential to understand/control their biological functions and aid the development of novel…”
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17
Computational Modeling of DNA 3D Structures: From Dynamics and Mechanics to Folding
Published in Molecules (Basel, Switzerland) (17-06-2023)“…DNA carries the genetic information required for the synthesis of RNA and proteins and plays an important role in many processes of biological development…”
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18
ABC2A: A Straightforward and Fast Method for the Accurate Backmapping of RNA Coarse-Grained Models to All-Atom Structures
Published in Molecules (Basel, Switzerland) (11-03-2024)“…RNAs play crucial roles in various essential biological functions, including catalysis and gene regulation. Despite the widespread use of coarse-grained (CG)…”
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19
Per- and perfluoroalkyl substances alternatives, mixtures and liver function in adults: A community-based population study in China
Published in Environment international (01-05-2022)“…[Display omitted] Experimental evidence has shown that per- and polyfluoroalkyl substances (PFAS) alternatives and mixtures may exert hepatotoxic effects in…”
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20
ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion
Published in The Journal of cell biology (07-01-2019)“…Mutations in cause Kufor-Rakeb syndrome, an autosomal recessive form of juvenile-onset atypical Parkinson's disease (PD). Recent work tied to autophagy and…”
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