Search Results - "Tan, Wilson L W"
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Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo
Published in Nature communications (09-08-2017)“…Cardiac regeneration may revolutionize treatment for heart failure but endogenous progenitor-derived cardiomyocytes in the adult mammalian heart are few and…”
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Genomic enhancers in cardiac development and disease
Published in Nature reviews cardiology (01-01-2022)“…The Human Genome Project marked a major milestone in the scientific community as it unravelled the ~3 billion bases that are central to crucial aspects of…”
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A landscape of circular RNA expression in the human heart
Published in Cardiovascular research (01-03-2017)“…Circular RNA (circRNA) is a newly validated class of single-stranded RNA, ubiquitously expressed in mammalian tissues and possessing key functions including…”
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Long noncoding RNA VENTHEART is required for ventricular cardiomyocyte specification and function
Published in Journal of molecular and cellular cardiology (01-12-2024)“…Cardiac-expressed long noncoding RNAs (lncRNAs) are important for cardiomyocyte (CM) differentiation and function. Several lncRNAs have been identified and…”
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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
Published in Nature genetics (01-01-2022)“…We determined the relationships between DNA sequence variation and DNA methylation using blood samples from 3,799 Europeans and 3,195 South Asians. We identify…”
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Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
Published in Nature genetics (01-01-2022)“…We determined the relationships between DNA sequence variation and DNA methylation using blood samples from 3,799 Europeans and 3,195 South Asians. We identify…”
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A Transcriptomic and Epigenomic Comparison of Fetal and Adult Human Cardiac Fibroblasts Reveals Novel Key Transcription Factors in Adult Cardiac Fibroblasts
Published in JACC. Basic to translational science (01-12-2016)“…Visual Abstract…”
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