Search Results - "Tan, Wendy"

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection by Jin, Hyun-Tak, Anderson, Ana C., Tan, Wendy G., West, Erin E., Ha, Sang-Jun, Araki, Koichi, Freeman, Gordon J., Kuchroo, Vijay K., Ahmed, Rafi

“…Inhibitory receptors play a crucial role in regulating CD8 T-cell function during chronic viral infection. T-cell Ig- and mucin-domain–containing molecule–3…”
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Autophagy is essential for effector CD8+ T cell survival and memory formation by Xu, Xiaojin, Araki, Koichi, Li, Shuzhao, Han, Jin-Hwan, Ye, Lilin, Tan, Wendy G, Konieczny, Bogumila T, Bruinsma, Monique W, Martinez, Jennifer, Pearce, Erika L, Green, Douglas R, Jones, Dean P, Virgin, Herbert W, Ahmed, Rafi

“…Autophagy has essential roles in cellular energy mobilization and homeostasis, but its role in T cell memory formation is remains poorly understood. Ahmed and…”
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Tight Regulation of Memory CD8+ T Cells Limits Their Effectiveness during Sustained High Viral Load by West, Erin E., Youngblood, Ben, Tan, Wendy G., Jin, Hyun-Tak, Araki, Koichi, Alexe, Gabriela, Konieczny, Bogumila T., Calpe, Silvia, Freeman, Gordon J., Terhorst, Cox, Haining, W. Nicholas, Ahmed, Rafi

“…To design successful vaccines for chronic diseases, an understanding of memory CD8+ T cell responses to persistent antigen restimulation is critical. However,…”
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Blue cone monochromacy and gene therapy by Sechrest, Emily R., Chmelik, Kathryn, Tan, Wendy D., Deng, Wen-Tao

“…Blue cone monochromacy (BCM) is a congenital vision disorder characterized by complete loss or severely reduced long- and middle-wavelength cone function,…”
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PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells by West, Erin E, Jin, Hyun-Tak, Rasheed, Ata-Ur, Penaloza-Macmaster, Pablo, Ha, Sang-Jun, Tan, Wendy G, Youngblood, Ben, Freeman, Gordon J, Smith, Kendall A, Ahmed, Rafi

“…The inhibitory receptor programmed cell death 1 (PD-1) plays a major role in functional exhaustion of T cells during chronic infections and cancer, and recent…”
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Qualitative differences in cellular immunogenicity elicited by hepatitis C virus T-Cell vaccines employing prime-boost regimens by Tan, Wendy G, Zubkova, Iryna, Kachko, Alla, Wells, Frances, Adler, Heiko, Sutter, Gerd, Major, Marian E

“…T-cell based vaccines have been considered as attractive candidates for prevention of hepatitis C virus (HCV) infections. In this study we compared the…”
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Fundus Albipunctatus Associated with Biallelic LRAT Gene Mutation: A Case Report with Long-Term Follow-Up by Tan, Wendy D, Odom, J. Vernon, Leys, Monique

“…This case report presents a 26-year-old female patient diagnosed with fundus albipunctatus (FAP), a rare form of congenital stationary night blindness. The…”
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Comparative Analysis of Simian Immunodeficiency Virus Gag-Specific Effector and Memory CD8+ T Cells Induced by Different Adenovirus Vectors by Tan, Wendy G, Jin, Hyun-Tak, West, Erin E, Penaloza-MacMaster, Pablo, Wieland, Andreas, Zilliox, Michael J, McElrath, M Juliana, Barouch, Dan H, Ahmed, Rafi

“…OA  Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Mutations of the histone linker H1–4 in neurodevelopmental disorders and functional characterization of neurons expressing C-terminus frameshift mutant H1.4 by Tremblay, Martine W, Green, Matthew V, Goldstein, Benjamin M, Aldridge, Andrew I, Rosenfeld, Jill A, Streff, Haley, Tan, Wendy D, Craigen, William, Bekheirnia, Nasim, Al Tala, Saeed, West, Anne E, Jiang, Yong-hui

“…Abstract Rahman syndrome (RMNS) is a rare genetic disorder characterized by mild to severe intellectual disability, hypotonia, anxiety, autism spectrum…”
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mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses by Ye, Lilin, Lee, Junghwa, Xu, Lifan, Mohammed, Ata-Ur-Rasheed, Li, Weiyan, Hale, J Scott, Tan, Wendy G, Wu, Tuoqi, Davis, Carl W, Ahmed, Rafi, Araki, Koichi

“…mTOR has important roles in regulation of both innate and adaptive immunity, but whether and how mTOR modulates humoral immune responses have yet to be fully…”
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Spatial data and workflow automation for understanding densification patterns and transport energy networks in urban areas: The cases of Bergen, Norway, and Zürich, Switzerland by de Koning, Remco Elric, Heldal, Rogardt, Tan, Wendy

“…A better understanding of how the spatial configuration of cities, understood as urban structure and forms, can achieve sustainable development is needed. This…”
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You have to drive: Impacts of planning policies on urban form and mobility behavior in Kuala Lumpur, Malaysia by Hidayati, Isti, Yamu, Claudia, Tan, Wendy

“…This article investigates how planning policies have shaped urban form and mobility behavior in the rapidly urbanized metropolitan area of Kuala Lumpur,…”
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Right-Sided Versus Left-Sided Pneumonectomy After Induction Therapy for Non-Small Cell Lung Cancer by Yang, Chi-Fu Jeffrey, Shah, Shivani A., Lin, Belle K., VanDusen, Keith W., Chan, Derek Y., Tan, Wendy D., Ranney, David N., Cox, Morgan L., D’Amico, Thomas A., Berry, Mark F.

“…A right-sided pneumonectomy after induction therapy for non-small cell lung cancer (NSCLC) has been shown to be associated with significant perioperative risk…”
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Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells by Iyer, Smita S, Chatraw, Janel Hart, Tan, Wendy G, Wherry, E John, Becker, Todd C, Ahmed, Rafi, Kapasi, Zoher F

“…Nutrition is a critical but poorly understood determinant of immunity. There is abundant epidemiological evidence linking protein malnutrition to impaired…”
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Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice by Schaefer, Patrick M., Huang, Jessica, Butic, Arrienne, Perry, Caroline, Yardeni, Tal, Tan, Wendy, Morrow, Ryan, Baur, Joseph A., Wallace, Douglas C.

“…Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1…”
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PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans by Kim, Heesun, Ding, Yue-He, Lu, Shan, Zuo, Mei-Qing, Tan, Wendy, Conte, Jr, Darryl, Dong, Meng-Qiu, Mello, Craig C

“…Germlines shape and balance heredity, integrating and regulating information from both parental and foreign sources. Insights into how germlines handle…”
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Endoscopic variceal ligation as primary prophylaxis for oesophageal variceal bleeding at a Malaysian tertiary hospital by Wendy Tan, A Y, Chieng, J Y

“…Approximately one-third of patients with esophageal varices will develop bleeding which is a major cause of morbidity and mortality in patients with liver…”
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EEG: Characteristics of drug-induced seizures in rats, dogs and non-human primates by Authier, Simon, Arezzo, Joseph, Pouliot, Mylène, Accardi, Michael V., Boulay, Emmanuel, Troncy, Eric, Dubuc Mageau, Michelle, Tan, Wendy, Sanfacon, Audrey, Mignault Goulet, Stephanie, Paquette, Dominique

“…Seizures are amongst the most frequent neurological issues encountered in pre-clinical safety testing. The objective was to characterize EEG morphologies and…”
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Comparative genomic analyses of frog virus 3, type species of the genus Ranavirus (family Iridoviridae) by Tan, Wendy G.H, Barkman, Todd J, Gregory Chinchar, V, Essani, Karim

“…Frog virus 3 (FV3) is the type species member of the genus Ranavirus (family Iridoviridae). To better understand the molecular mechanisms involved in the…”
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Inhibition of Hepatitis C Virus by the Cyanobacterial Protein Microcystis viridis Lectin: Mechanistic Differences between the High-Mannose Specific Lectins MVL, CV-N, and GNA by Kachko, Alla, Loesgen, Sandra, Shahzad-ul-Hussan, Syed, Tan, Wendy, Zubkova, Iryna, Takeda, Kazuyo, Wells, Frances, Rubin, Steven, Bewley, Carole A, Major, Marian E

“…Plant or microbial lectins are known to exhibit potent antiviral activities against viruses with glycosylated surface proteins, yet the mechanism(s) by which…”
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