Search Results - "Tan, Wan Ling"
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Novel therapeutic targets on the horizon for lung cancer
Published in The lancet oncology (01-08-2016)“…Summary Lung cancer is a leading cause of cancer-related mortality worldwide, and is classically divided into two major histological subtypes: non-small-cell…”
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From presentation to paper: Gender disparities in oncological research
Published in International journal of cancer (01-06-2020)“…Gender disparities in scientific publications have been identified in oncological research. Oral research presentations at major conferences enhance visibility…”
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Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases
Published in BMC cancer (03-12-2018)“…Afatinib is an oral irreversible epidermal growth factor receptor (EGFR) tyrosine-kinase inhibitor (TKI) indicated in first-line treatment of advanced…”
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Clinical efficacy and biomarker analysis of dual PD-1/CTLA-4 blockade in recurrent/metastatic EBV-associated nasopharyngeal carcinoma
Published in Nature communications (15-05-2023)“…Single-agent checkpoint inhibitor (CPI) activity in Epstein-Barr Virus (EBV) related nasopharyngeal carcinoma (NPC) is limited. Dual CPI shows increased…”
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Correction to: Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases
Published in BMC cancer (24-12-2018)Get full text
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Comparison of hepatocellular carcinoma in Eastern versus Western populations
Published in Cancer (15-11-2016)“…Hepatocellular carcinoma (HCC) is a heterogeneous disease that remains highly prevalent in many Asian countries and is the second most common cause of…”
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Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer
Published in Journal of clinical oncology (10-04-2019)“…Mesenchymal epithelial transition factor ( MET) activation has been implicated as an oncogenic driver in epidermal growth factor receptor ( EGFR)-mutant…”
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Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and cost-effectiveness analysis
Published in Lung cancer (Amsterdam, Netherlands) (01-01-2020)“…•Upfront NGS is feasible and cost-effective in an EGFR mutant predominant population.•Characterizing the wider genomic profile may yield important…”
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EGFR Mutation Subtypes Influence Survival Outcomes following First-Line Gefitinib Therapy in Advanced Asian NSCLC Patients
Published in Journal of thoracic oncology (01-03-2017)“…Activating mutations in the EGFR gene have been shown to confer sensitivity to EGFR tyrosine kinase inhibitors in patients with advanced NSCLC. However, wide…”
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Asian Thoracic Oncology Research Group Expert Consensus Statement on Optimal Management of Stage III NSCLC
Published in Journal of thoracic oncology (01-03-2020)“…Stage III NSCLC represents a heterogeneous disease for which optimal treatment continues to pose a clinical challenge. Recent changes in the American Joint…”
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Real-world outcomes of pemetrexed-platinum chemotherapy plus osimertinib after progression on first-line osimertinib in advanced EGFR-mutated NSCLC
Published in Lung cancer (Amsterdam, Netherlands) (01-07-2024)“…•Addition of pemetrexed-platinum on first-line osimertinib progression is effective.•Patients with L858R and baseline CNS metastases also benefit from this…”
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Advances in systemic treatment for nasopharyngeal carcinoma
Published in Chinese Clinical Oncology (01-04-2016)“…Nasopharyngeal carcinoma (NPC) is a unique disease endemic in Asia. It is etiologically linked to the Epstein-Barr virus and is both radio- and…”
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Multispectral raster-scanning optoacoustic mesoscopy differentiate lesional from non-lesional atopic dermatitis skin using structural and functional imaging markers
Published in Photoacoustics (Munich) (01-12-2022)“…Atopic dermatitis (AD) is a chronic and pruritic skin inflammatory disease causing a significant burden to health care management and patient’s quality of…”
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Healthcare policy for COVID‐19 patients on haemodialysis: Adapting to the changing needs of the Omicron variant
Published in Nephrology (Carlton, Vic.) (01-10-2022)Get full text
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Brief Report: Droplet Digital Polymerase Chain Reaction Versus Plasma Next-Generation Sequencing in Detecting Clearance of Plasma EGFR Mutations and Carcinoembryonic Antigen Levels as a Surrogate Measure
Published in JTO clinical and research reports (01-12-2023)“…To compare the performance of droplet digital polymerase chain reaction (ddPCR) and plasma next-generation sequencing (NGS) in detecting clearance of plasma…”
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Abstract 5114: Ultra-sensitive detection of minimal residual disease (MRD) through whole genome sequencing (WGS) using an AI-based error suppression model in resected early-stage non-small cell lung cancer (NSCLC)
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Background: Early detection of recurrence and monitoring of MRD post-surgery is critical for clinical decision-making to tailor adjuvant therapy. In…”
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Is There a Unicorn Among the Uncommon EGFR Mutations?
Published in Journal of thoracic oncology (01-02-2023)Get more information
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Real world outcomes of patients with non-clear cell renal cell carcinoma: A single Asian centre experience
Published in Journal of clinical oncology (20-02-2023)“…632 Background: Non-clear cell RCC (nccRCC) represents a heterogenous group of tumors which is less well studied than clear cell RCC. Clinical data supporting…”
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Real-world outcomes of pemetrexed-platinum chemotherapy plus osimertinib after progression on first-line osimertinib in advanced EGFR-mutated NSCLC
Published in Journal of clinical oncology (01-06-2024)“…e20531 Background: First-line pemetrexed-platinum chemotherapy + osimertinib (Pem-Plat-Osi) improves progression free survival as compared to osimertinib (Osi)…”
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Elucidating the genomic and transcriptomic landscape of L858R vs ex19del EGFR-mutated NSCLC
Published in Journal of clinical oncology (01-06-2023)“…8530 Background: Epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) is heterogeneous and L858R derive less benefit from…”
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