Search Results - "Tan, Tiak Ju"

Mechanisms and biomarkers of subcutaneous immunotherapy and sublingual immunotherapy in allergen immunotherapy by Tan, Tiak Ju, Layhadi, Janice A, Shamji, Mohamed H

“…There are currently no biomarkers that can accurately predict clinical outcomes and segregate responders from nonresponders in allergen immunotherapy (AIT)…”
Get more information

Age-Related Alterations in Macrophage Distribution and Function Are Associated With Delayed Cutaneous Wound Healing by Dube, Christabel Thembela, Ong, Yasmin Hui Binn, Wemyss, Kelly, Krishnan, Siddharth, Tan, Tiak Ju, Janela, Baptiste, Grainger, John R, Ronshaugen, Matthew, Mace, Kimberly A, Lim, Chin Yan

“…Ageing-related delays and dysregulated inflammation in wound healing are well-documented in both human and animal models. However, cellular and molecular…”
Get full text

Divergent functions of histone acetyltransferases KAT2A and KAT2B in keratinocyte self-renewal and differentiation by Walters, Benjamin William, Tan, Tiak Ju, Tan, Chew Teng, Dube, Christabel Thembela, Lee, Kang Ting, Koh, Jace, Ong, Yasmin Hui Binn, Tan, Vanessa Xue Hui, Jahan, Fathima Rifkhana Shah, Lim, Xin Ni, Wan, Yue, Lim, Chin Yan

“…The mammalian epidermis undergoes constant renewal, replenished by a pool of stem cells and terminal differentiation of their progeny. This is accompanied by…”
Get full text

Single-cell RNA sequencing identifies precise tolerogenic cellular and molecular pathways induced by depigmented-polymerized grass pollen allergen extract by Layhadi, Janice A., Moya, Raquel, Tan, Tiak Ju, Lenormand, Madison M., Sharif, Hanisah, Parkin, Rebecca V., Vila-Nadal, Gemma, Fedina, Oleksandra, Zhu, Rongfei, Laisuan, Wannada, Durham, Stephen R., Carnés, Jerónimo, Shamji, Mohamed H.

“…[Display omitted] Immunologic mechanism of action of allergoids remains poorly understood. Previous models of allergenicity and immunogenicity have yielded…”
Get full text

Elucidating allergic reaction mechanisms in response to SARS‐CoV‐2 mRNA vaccination in adults by Shah, Mihir M., Layhadi, Janice A., Hourcade, Dennis E., Fulton, William T., Tan, Tiak Ju, Dunham, Diane, Chang, Iris, Vel, Monica S., Fernandes, Andrea, Lee, Alexandra S., Liu, James, Arunachalam, Prabhu S., Galli, Stephen J., Boyd, Scott D., Pulendran, Bali, Davis, Mark M., O'Hara, Ruth, Park, Helen, Mitchell, Lynne M., Akk, Antonina, Patterson, Alexander, Jerath, Maya R., Monroy, Jennifer M., Ren, Zhen, Kendall, Peggy L., Durham, Stephen R., Fedina, Aleksandra, Gibbs, Bernhard F., Agache, Ioana, Chinthrajah, Sharon, Sindher, Sayantani B., Heider, Anja, Akdis, Cezmi A., Shamji, Mohamed H., Pham, Christine T. N., Nadeau, Kari C.

“…Background During the COVID‐19 pandemic, novel nanoparticle‐based mRNA vaccines were developed. A small number of individuals developed allergic reactions to…”
Get full text

Deciphering the role of platelets in severe allergy by an integrative omics approach by Pablo‐Torres, Carmela, Izquierdo, Elena, Tan, Tiak Ju, Obeso, David, Layhadi, Janice A., Sánchez‐Solares, Javier, Mera‐Berriatua, Leticia, Bueno‐Cabrera, José Luis, Mar Reaño‐Martos, María, Iglesias‐Cadarso, Alfredo, Barbas, Coral, Gomez‐Casado, Cristina, Villaseñor, Alma, Barber, Domingo, Shamji, Mohamed H., Escribese, María M.

“…Background Mechanisms causing the onset and perpetuation of inflammation in severe allergic patients remain unknown. Our previous studies suggested that severe…”
Get full text

Abstract 6235: Clinical and phenotypic consequences of HLA mediated antigen presentation deficiency in pancreatic adenocarcinoma at bulk and single-cell resolution by Geuenich, Michael J., Gruenwald, Barbara, O'Kane, Grainne, Yu, Chengxin, Ju, Tan Tiak, Zhang, Amy, Hamza, Oumaima, Jang, Gun Ho, Notta, Faiyaz, Gallinger, Steven, Campbell, Kieran R.

“…Abstract Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal neoplasm of the pancreas characterized by a low survival rate and limited…”
Get full text

Biomarkers of AIT: Models of prediction of efficacy by Tan, Tiak Ju, Delgado-Dolset, María I., Escribese, María M., Barber, Domingo, Layhadi, Janice A., Shamji, Mohamed H.

“…Allergic rhinitis is an IgE-mediated inflammation that remains a clinical challenge, affecting 40% of the UK population with a wide range of severity from…”
Get full text

Single-cell RNA-Seq identifies precise tolerogenic cellular and molecular pathways induced by depigmented-polymerized grass pollen allergen extract by Layhadi, Janice, Lobo, Raquel Moya, Ju, Tan Tiak, Burki, Madison, Hj Awg Sharif Hj Awg Sharif, Hjh Hanisah, Parkin, Rebecca, Vila-Nadal, Gemma, Fedina, Oleksandra, Durham, Stephen, Carnes, Jeronimo, Shamji, Mohamed

Get full text