Search Results - "Tan, Sabrina C."

Landscape of Human Immunodeficiency Virus Neutralization Susceptibilities Across Tissue Reservoirs by Wang, Chuangqi, Schlub, Timothy E, Yu, Wen Han, Tan, C Sabrina, Stefic, Karl, Gianella, Sara, Smith, Davey M, Lauffenburger, Douglas A, Chaillon, Antoine, Julg, Boris

“…Human immunodeficiency virus type 1 (HIV-1) sequence diversity and the presence of archived epitope muta-tions in antibody binding sites are a major obstacle…”
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Immunotherapeutics to Treat HIV in the Central Nervous System by Kapoor, Andrew, Tan, C. Sabrina

“…Purpose of Review The application of immunotherapies to HIV presents a new horizon of treatment options, but little is known about what impact they may have on…”
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Immunogenicity of 2 therapeutic mosaic HIV-1 vaccine strategies in individuals with HIV-1 on antiretroviral therapy by Julg, Boris, Stephenson, Kathryn E., Tomaka, Frank, Walsh, Stephen R., Sabrina Tan, C., Lavreys, Ludo, Sarnecki, Michal, Ansel, Jessica L., Kanjilal, Diane G., Jaegle, Kate, Speidel, Tessa, Nkolola, Joseph P., Borducchi, Erica N., Braams, Esmee, Pattacini, Laura, Burgess, Eleanor, Ilan, Shlomi, Bartsch, Yannic, Yanosick, Katherine E., Seaman, Michael S., Stieh, Daniel J., van Duijn, Janine, Willems, Wouter, Robb, Merlin L., Michael, Nelson L., Walker, Bruce D., Pau, Maria Grazia, Schuitemaker, Hanneke, Barouch, Dan H.

“…Mosaic HIV-1 vaccines have been shown to elicit robust humoral and cellular immune responses in people living with HIV-1 (PLWH), that had started…”
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Increased IL-6 expression precedes reliable viral detection in the rhesus macaque brain during acute SIV infection by Gopalakrishnan, Raja Mohan, Aid, Malika, Mercado, Noe B, Davis, Caitlin, Malik, Shaily, Geiger, Emma, Varner, Valerie, Jones, Rhianna, Bosinger, Steven E, Piedra-Mora, Cesar, Martinot, Amanda J, Barouch, Dan H, Reeves, R Keith, Tan, C Sabrina

“…Knowledge of immune activation in the brain during acute HIV infection is crucial for the prevention and treatment of HIV-associated neurological disorders. We…”
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Comparing Urine and Blood Screening Methods to Detect BK Virus After Renal Transplant by McGann, Kevin, DeWolfe, David, Jacobs, Marie, Wojciechowski, David, Pavlakis, Martha, Tan, C Sabrina

“…BK polyomavirus can infect healthy individuals; however, in renal transplant recipients, it can cause nephropathy, which can lead to renal allograftfailure…”
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HIV on the brain: is neurosignalling damage irreversible even on antiretroviral therapy? by Tan, C. Sabrina, Reeves, R. Keith

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Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials by Modjarrad, Kayvon, Lin, Leyi, George, Sarah L, Stephenson, Kathryn E, Eckels, Kenneth H, De La Barrera, Rafael A, Jarman, Richard G, Sondergaard, Erica, Tennant, Janice, Ansel, Jessica L, Mills, Kristin, Koren, Michael, Robb, Merlin L, Barrett, Jill, Thompson, Jason, Kosel, Alison E, Dawson, Peter, Hale, Andrew, Tan, C Sabrina, Walsh, Stephen R, Meyer, Keith E, Brien, James, Crowell, Trevor A, Blazevic, Azra, Mosby, Karla, Larocca, Rafael A, Abbink, Peter, Boyd, Michael, Bricault, Christine A, Seaman, Michael S, Basil, Anne, Walsh, Melissa, Tonwe, Veronica, Hoft, Daniel F, Thomas, Stephen J, Barouch, Dan H, Michael, Nelson L

“…A safe, effective, and rapidly scalable vaccine against Zika virus infection is needed. We developed a purified formalin-inactivated Zika virus vaccine (ZPIV)…”
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Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial by Julg, Boris, Stephenson, Kathryn E., Wagh, Kshitij, Tan, Sabrina C., Zash, Rebecca, Walsh, Stephen, Ansel, Jessica, Kanjilal, Diane, Nkolola, Joseph, Walker-Sperling, Victoria E. K., Ophel, Jasper, Yanosick, Katherine, Borducchi, Erica N., Maxfield, Lori, Abbink, Peter, Peter, Lauren, Yates, Nicole L., Wesley, Martina S., Hassell, Tom, Gelderblom, Huub C., deCamp, Allen, Mayer, Bryan T., Sato, Alicia, Gerber, Monica W., Giorgi, Elena E., Gama, Lucio, Koup, Richard A., Mascola, John R., Monczor, Ana, Lupo, Sofia, Rolle, Charlotte-Paige, Arduino, Roberto, DeJesus, Edwin, Tomaras, Georgia D., Seaman, Michael S., Korber, Bette, Barouch, Dan H.

“…HIV-1 therapy with single or dual broadly neutralizing antibodies (bNAbs) has shown viral escape, indicating that at least a triple bNAb therapy may be needed…”
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Upregulation of the NKG2D Ligand ULBP2 by JC Polyomavirus Infection Promotes Immune Recognition by Natural Killer Cells by Jost, Stephanie, Ahn, Jenny, Chen, Sarah, Yoder, Taylor, Gikundiro, Kayitare Eunice, Lee, Esther, Gressens, Simon B, Kroll, Kyle, Craemer, Melissa, Kaynor, G Campbell, Lifton, Michelle, Tan, C Sabrina

“…JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a potentially fatal complication of severe immune suppression with no…”
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Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial by Stephenson, Kathryn E., Julg, Boris, Tan, C. Sabrina, Zash, Rebecca, Walsh, Stephen R., Rolle, Charlotte-Paige, Monczor, Ana N., Lupo, Sofia, Gelderblom, Huub C., Ansel, Jessica L., Kanjilal, Diane G., Maxfield, Lori F., Nkolola, Joseph, Borducchi, Erica N., Abbink, Peter, Liu, Jinyan, Peter, Lauren, Chandrashekar, Abishek, Nityanandam, Ramya, Lin, Zijin, Setaro, Alessandra, Sapiente, Joseph, Chen, Zhilin, Sunner, Lisa, Cassidy, Tyler, Bennett, Chelsey, Sato, Alicia, Mayer, Bryan, Perelson, Alan S., deCamp, Allan, Priddy, Frances H., Wagh, Kshitij, Giorgi, Elena E., Yates, Nicole L., Arduino, Roberto C., DeJesus, Edwin, Tomaras, Georgia D., Seaman, Michael S., Korber, Bette, Barouch, Dan H.

“…Human immunodeficiency virus (HIV)-1-specific broadly neutralizing monoclonal antibodies are currently under development to treat and prevent HIV-1 infection…”
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Characteristics of Progressive Multifocal Leukoencephalopathy Associated With Sarcoidosis Without Therapeutic Immune Suppression by McEntire, Caleb R S, Fletcher, Anita, Toledano, Michel, Epstein, Samantha, White, Emily, Tan, C Sabrina, Mao-Draayer, Yang, Banks, Samantha A, Aksamit, Allen J, Gelfand, Jeffrey M, Thakur, Kiran T, Anand, Pria, Cortese, Irene, Bhattacharyya, Shamik

“…Progressive multifocal leukoencephalopathy can occur in the context of systemic sarcoidosis (S-PML) in the absence of therapeutic immune suppression and can…”
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Durability of Heterologous and Homologous COVID-19 Vaccine Boosts by Tan, C Sabrina, Collier, Ai-Ris Y, Yu, Jingyou, Liu, Jinyan, Chandrashekar, Abishek, McMahan, Katherine, Jacob-Dolan, Catherine, He, Xuan, Roy, Vicky, Hauser, Blake M, Munt, Jennifer E, Mallory, Michael L, Mattocks, Melissa, Powers, John M, Meganck, Rita M, Rowe, Marjorie, Hemond, Rachel, Bondzie, Esther A, Jaegle, Kate H, Baric, Ralph S, Schmidt, Aaron G, Alter, Galit, Le Gars, Mathieu, Sadoff, Jerald, Barouch, Dan H

“…Antibody responses elicited by current messenger RNA (mRNA) COVID-19 vaccines decline rapidly and require repeated boosting. To evaluate the immunogenicity and…”
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CSF viral escape in a patient with HIV-associated neurocognitive disorder by Khoury, Michael N., Tan, C. Sabrina, Peaslee, Marcia, Koralnik, Igor J.

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Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17–22) by Stephenson, Kathryn E, Wegmann, Frank, Tomaka, Frank, Walsh, Stephen R, Tan, C Sabrina, Lavreys, Ludo, Ansel, Jessica L, Kanjilal, Diane G, Jaegle, Kate, Nkolola, Joseph P, Peter, Lauren, Fogel, Rachel, Bradshaw, Connor, Tyler, Anna, Makoni, Tatenda, Howe, Lisa, Quijada, Darla, Chandrashekar, Abishek, Bondzie, Esther A, Borducchi, Erica N, Yanosick, Katherine E, Hendriks, Jenny, Nijs, Steven, Truyers, Carla, Tolboom, Jeroen, Zahn, Roland C, Seaman, Michael S, Alter, Galit, Stieh, Daniel J, Pau, Maria Grazia, Schuitemaker, Hanneke, Barouch, Dan H

“…Current efficacy studies of a mosaic HIV-1 prophylactic vaccine require four vaccination visits over one year, which is a complex regimen that could prove…”
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Bridging the gaps between JCV infection models and human disease by Cortese, Irene, Tan, C Sabrina

“…This scientific commentary refers to ‘JC virus spread is potentiated by glial replication and demyelination-linked glial proliferation’ by Li et al…”
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HIV on the Brain: Is neurosignaling damage irreversible even on ART? by Tan, C. Sabrina, Reeves, R. Keith

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Elucidating the role played by the NKG2 family of receptors in natural killer cell responses to JC polyomavirus by Lee, Esther, Ahn, Jenny, Chen, Sarah, Gikundiro, Kayitare Eunice, Craemer, Melissa, Gressens, Simon, Yoder, Taylor, Lifton, Michelle, Tan, C. Sabrina, Jost, Stephanie

“…Abstract JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a potentially fatal complication of severe immune suppression due to…”
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Neuroborreliosis: A Case Report on an Unusual Cause of Orbital Inflammation by He, Kevin D., Al Lawati, Hawra, Torun, Nurhan, Tan, C. Sabrina

“…Background Neuroborreliosis is involvement of the nervous system in Lyme disease and can often be overlooked as a diagnosis in patients presenting with cranial…”
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306. Determining natural killer cell responses to JC polyomavirus by Tan, C Sabrina, Ahn, Jenny, Chen, Sarah, Lee, Esther, Gikundiro, Eunice, Craemer, Melissa, Gressens, Simon, Yoder, Taylor, Lifton, Michelle, Jost, Stephanie

“…Abstract Background JC polyomavirus (JCPyV) infects oligodendrocytes and causes progressive multifocal leukoencephalopathy (PML), a potentially fatal…”
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Safety and immunogenicity of a purified inactivated Zika virus vaccine candidate given via standard versus accelerated vaccination schedules: a phase 1, single-center, double-blind, sequential-group, randomized, placebo-controlled clinical trial by Stephenson, Kathryn E., Tan, C. Sabrina, Walsh, Stephen R., Hale, Andrew, Ansel, Jessica L., Kanjilal, Diane G., Jaegle, Kate, Peter, Lauren, Borducchi, Erica N., Nkolola, Joseph, Makoni, Tatenda, Fogel, Rachel, Bradshaw, Connor, Tyler, Anna, Moseley, Edward, Chandrashekar, Abishek, Yanosick, Katherine E., Seaman, Michael S., Eckels, Kenneth H., De La Barrera, Rafael A., Thompson, Jason, Dawson, Peter, Thomas, Stephen J., Michael, Nelson L., Modjarrad, Kayvon, Barouch, Dan H.

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