Search Results - "Tan, Ruensern"

Cooperative Accumulation of Dynein-Dynactin at Microtubule Minus-Ends Drives Microtubule Network Reorganization by Tan, Ruensern, Foster, Peter J., Needleman, Daniel J., McKenney, Richard J.

“…Cytoplasmic dynein-1 is a minus-end-directed motor protein that transports cargo over long distances and organizes the intracellular microtubule (MT) network…”
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Inhibiting Insulin-Mediated β2-Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction by Wang, Qingtong, Liu, Yongming, Fu, Qin, Xu, Bing, Zhang, Yuan, Kim, Sungjin, Tan, Ruensern, Barbagallo, Federica, West, Toni, Anderson, Ethan, Wei, Wei, Abel, E Dale, Xiang, Yang K

“…Type 2 diabetes mellitus (DM) and obesity independently increase the risk of heart failure by incompletely understood mechanisms. We propose that…”
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Structure and Mechanics of Dynein Motors by Canty, John T, Tan, Ruensern, Kusakci, Emre, Fernandes, Jonathan, Yildiz, Ahmet

“…Dyneins make up a family of AAA+ motors that move toward the minus end of microtubules. Cytoplasmic dynein is responsible for transporting intracellular cargos…”
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Microtubules gate tau condensation to spatially regulate microtubule functions by Tan, Ruensern, Lam, Aileen J., Tan, Tracy, Han, Jisoo, Nowakowski, Dan W., Vershinin, Michael, Simó, Sergi, Ori-McKenney, Kassandra M., McKenney, Richard J.

“…Tau is an abundant microtubule-associated protein in neurons. Tau aggregation into insoluble fibrils is a hallmark of Alzheimer’s disease and other types of…”
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Inhibiting Insulin-Mediated β 2 -Adrenergic Receptor Activation Prevents Diabetes-Associated Cardiac Dysfunction by Wang, Qingtong, Liu, Yongming, Fu, Qin, Xu, Bing, Zhang, Yuan, Kim, Sungjin, Tan, Ruensern, Barbagallo, Federica, West, Toni, Anderson, Ethan, Wei, Wei, Abel, E. Dale, Xiang, Yang K.

“…Background: Type 2 diabetes mellitus (DM) and obesity independently increase the risk of heart failure by incompletely understood mechanisms. We propose that…”
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Microtubule lattice spacing governs cohesive envelope formation of tau family proteins by Siahaan, Valerie, Tan, Ruensern, Humhalova, Tereza, Libusova, Lenka, Lacey, Samuel E., Tan, Tracy, Dacy, Mariah, Ori-McKenney, Kassandra M., McKenney, Richard J., Braun, Marcus, Lansky, Zdenek

“…Tau is an intrinsically disordered microtubule-associated protein (MAP) implicated in neurodegenerative disease. On microtubules, tau molecules segregate into…”
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High-throughput single particle tracking reveals estrogen receptor protein interaction landscape in living cells by McSwiggen, David, Liu, Helen, Chen, Hanzhe, Heckert, Alec, Ho, Jaclyn, Johnson, Stephanie L., Akella, Lakshmi, Gonzalez, Eric, Hanuka, Adi, Li, Yan, Sule, Akshay, Pierce, Sarah, Tan, Ruensern, Beck, Hilary, Anderson, Daniel

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Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH by Charafeddine, Rabab A., Cortopassi, Wilian A., Lak, Parnian, Tan, Ruensern, McKenney, Richard J., Jacobson, Matthew P., Barber, Diane L., Wittmann, Torsten

“…Tau, a member of the MAP2/tau family of microtubule-associated proteins, stabilizes and organizes axonal microtubules in healthy neurons. In neurodegenerative…”
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Microtubules Gate Tau Condensation to Spatially Regulate Microtubule Functions by Tan, Ruensern, Lam, Aileen, Tan, Tracy, Han, Jisoo, Nowakowski, Dan W., Simo, Sergi, Vershinin, Michael, Ori-McKenney, Kassandra M., McKenney, Richard J.

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Microtubule Associated Protein Oligomerization on the Microtubule Generates New Functionalities by Tan, Ruensern

“…Microtubules (MT) are essential cytoskeletal components for all eukaryotic cell survival. They are both passive and active participants in all cellular…”
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Inhibiting Insulin-Mediated β2AR Activation Prevents Diabetes-Associated Cardiac Dysfunction by Wang, Qingtong, Liu, Yongming, Fu, Qin, Xu, Bing, Zhang, Yuan, Kim, Sungjin, Tan, Ruensern, Barbagallo, Federica, West, Toni, Anderson, Ethan, Wei, Wei, Abel, E Dale, Xiang, Yang K

“…BACKGROUND—Type-2 diabetes and obesity independently increases the risk of heart failure via incompletely understood mechanisms. We propose that…”
Get full text