Search Results - "Tan, Ming T"

Interpreting the CPASS Trial: Do Not Shift Motor Therapy to the Subacute Phase by Edwardson, Matthew A., Brady, Kathaleen, Giannetti, Margot L., Geed, Shashwati, Barth, Jessica, Mitchell, Abigail, Tan, Ming T., Zhou, Yizhao, Bregman, Barbara S., Newport, Elissa L., Edwards, Dorothy F., Dromerick, Alexander W.

“…The Critical Periods After Stroke Study (CPASS, n = 72) showed that, compared to controls, an additional 20 hours of intensive upper limb therapy led to…”
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Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer's Disease by Fiandaca, Massimo S, Zhong, Xiaogang, Cheema, Amrita K, Orquiza, Michael H, Chidambaram, Swathi, Tan, Ming T, Gresenz, Carole Roan, FitzGerald, Kevin T, Nalls, Mike A, Singleton, Andrew B, Mapstone, Mark, Federoff, Howard J

“…We recently documented plasma lipid dysregulation in preclinical late-onset Alzheimer's disease (LOAD). A 10 plasma lipid panel, predicted phenoconversion and…”
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A New Preprocedure Risk Score for Predicting Contrast-Induced Acute Kidney Injury by Duan, Chongyang, MD, Cao, Yingshu, MS, Liu, Yong, MD, Zhou, Lizhi, MD, Ping, Kaike, MS, Tan, Ming T., PhD, Tan, Ning, MD, FACC, FESC, Chen, Jiyan, MD, FACC, FESC, Chen, Pingyan, MS

“…Abstract Background Most of the risk models for predicting contrast-induced acute kidney injury (CI-AKI) are available for only postcontrast exposure…”
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Development and Validation of a Risk Score for Prediction of Acute Kidney Injury in Patients With Acute Decompensated Heart Failure: A Prospective Cohort Study in China by Zhou, Li Zhi, Yang, Xiao Bing, Guan, Ying, Xu, Xing, Tan, Ming T., Hou, Fan Fan, Chen, Ping Yan

“…Background Although several risk factors for acute kidney injury (AKI) have been identified, early detection of AKI in acute decompensated heart failure…”
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Estimation and Hypothesis Test for Mean Curve with Functional Data by Reproducing Kernel Hilbert Space Methods, with Applications in Biostatistics by Xiong, Ming, Yuan, Ao, Fang, Hong-Bin, Wu, Colin O., Tan, Ming T.

“…Functional data analysis has important applications in biomedical, health studies and other areas. In this paper, we develop a general framework for a mean…”
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Cyclin D1 gene ablation confers neuroprotection in traumatic brain injury by Kabadi, Shruti V, Stoica, Bogdan A, Loane, David J, Byrnes, Kimberly R, Hanscom, Marie, Cabatbat, Rainier M, Tan, Ming T, Faden, Alan I

“…Cell cycle activation (CCA) is one of the principal secondary injury mechanisms following brain trauma, and it leads to neuronal cell death, microglial…”
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Critical periods after stroke study: translating animal stroke recovery experiments into a clinical trial by Dromerick, Alexander W, Edwardson, Matthew A, Edwards, Dorothy F, Giannetti, Margot L, Barth, Jessica, Brady, Kathaleen P, Chan, Evan, Tan, Ming T, Tamboli, Irfan, Chia, Ruth, Orquiza, Michael, Padilla, Robert M, Cheema, Amrita K, Mapstone, Mark E, Fiandaca, Massimo S, Federoff, Howard J, Newport, Elissa L

“…Seven hundred ninety-five thousand Americans will have a stroke this year, and half will have a chronic hemiparesis. Substantial animal literature suggests…”
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Green tea protects rats against autoimmune arthritis by modulating disease-related immune events by Kim, Hong Ro, Rajaiah, Rajesh, Wu, Qing-Li, Satpute, Shailesh R, Tan, Ming T, Simon, James E, Berman, Brian M, Moudgil, Kamal D

“…Green tea, a product of the dried leaves of Camellia sinensis, is the most widely consumed beverage in the world. The polyphenolic compounds from green tea…”
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Pembrolizumab in patients with thymic carcinoma: a single-arm, single-centre, phase 2 study by Giaccone, Giuseppe, Kim, Chul, Thompson, Jillian, McGuire, Colleen, Kallakury, Bhaskar, Chahine, Joeffrey J, Manning, Maria, Mogg, Robin, Blumenschein, Wendy M, Tan, Ming T, Subramaniam, Deepa S, Liu, Stephen V, Kaplan, Ian M, McCutcheon, Justine N

“…Treatment options are limited for patients with thymic carcinoma. These aggressive tumours are not typically associated with paraneoplastic autoimmune…”
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Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans by Dromerick, Alexander W., Geed, Shashwati, Barth, Jessica, Brady, Kathaleen, Giannetti, Margot L., Mitchell, Abigail, Edwardson, Matthew A., Tan, Ming T., Zhou, Yizhao, Newport, Elissa L., Edwards, Dorothy F.

“…Restoration of human brain function after injury is a signal challenge for translational neuroscience. Rodent stroke recovery studies identify an optimal or…”
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Effect of Laser Moxibustion for Knee Osteoarthritis: A Multisite, Double-blind Randomized Controlled Trial by Zhao, Ling, Cheng, Ke, Wu, Fan, Du, Jiong, Chen, Yue, Tan, Ming T, Lao, Lixing, Shen, Xueyong

“…To examine the effects of laser moxibustion on pain and function in patients with knee osteoarthritis (OA). A double-blind randomized clinical trial (4-week…”
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Set‐regression with applications to subgroup analysis by Yuan, Ao, Wang, Lida, Tan, Ming T.

“…Regression is a commonly used statistical model. It is the conditional mean of the response given covariates μ(x)=E(Y|X=x). However, in some practical…”
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Subgroup analysis with semiparametric models toward precision medicine by Yuan, Ao, Chen, Xiaofei, Zhou, Yizhao, Tan, Ming T.

“…In analyzing clinical trials, one important objective is to classify the patients into treatment‐favorable and nonfavorable subgroups. Existing parametric…”
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Design and modeling for drug combination experiments with order effects by Huang, Hengzhen, Liu, Min‐Qian, Tan, Ming T., Fang, Hong‐Bin

“…Combinations of drugs are now ubiquitous in treating complex diseases such as cancer and HIV due to their potential for enhanced efficacy and reduced side…”
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Efficient statistical tests to compare Youden index: accounting for contingency correlation by Chen, Fangyao, Xue, Yuqiang, Tan, Ming T., Chen, Pingyan

“…Youden index is widely utilized in studies evaluating accuracy of diagnostic tests and performance of predictive, prognostic, or risk models. However, both one…”
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Identification of subgroups via partial linear regression modeling approach by Zhou, Yizhao, Yuan, Ao, Tan, Ming T.

“…In clinical trials, treatment effects often vary from subject to subject. Some subjects may benefit more than others from a specific treatment. One of the aims…”
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Robust estimates of regional treatment effects in multiregional randomized clinical trials with ordinal responses by Duan, Chongyang, Yuan, Ao, Tan, Ming T.

“…Global clinical trials involving multiple regions are common in current drug development processes. Determining the regional treatment effects of a new therapy…”
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Doubly Robust Semiparametric Estimation for Multi-group Causal Comparisons by Yin, Anqi, Yuan, Ao, Tan, Ming T.

“…In biomedical research, especially in epidemiological studies, we often need to compare nonrandomized groups, as randomization is only sometimes feasible. Even…”
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Subgroup analysis with a nonparametric unimodal symmetric error distribution by Yuan, Ao, Zhou, Yizhao, Tan, Ming T.

“…In clinical trials and moving toward precision medicine, a very key issue is identifying subgroups of patients with different responses to therapy, namely,…”
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Experimental Design for Multi-Drug Combination Studies Using Signaling Networks by Huang, Hengzhen, Fang, Hong-Bin, Tan, Ming T.

“…Combinations of multiple drugs are an important approach to maximize the chance for therapeutic success by inhibiting multiple pathways/targets. Analytic…”
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