Search Results - "Tan, Mengzhu"

Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation by Gu, Mengru, Jiang, Hanlu, Tan, Mengzhu, Yu, Long, Xu, Ning, Li, Ying, Wu, Han, Hou, Qing, Dai, Chunsun

“…palmitoylation, a reversible post-translational modification, is initiated by the DHHC family of palmitoyltransferases and reversed by several acyl protein…”
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PP2Acα promotes macrophage accumulation and activation to exacerbate tubular cell death and kidney fibrosis through activating Rap1 and TNFα production by Liang, Yan, Sun, Xiaoli, Wang, Mingjie, Lu, Qingmiao, Gu, Mengru, Zhou, Lu, Hou, Qing, Tan, Mengzhu, Wang, Sudan, Xue, Xian, Dai, Chunsun

“…Macrophage accumulation and activation play an essential role in kidney fibrosis; however, the underlying mechanisms remain to be explored. By analyzing the…”
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The Hippo Coactivator TAZ Exacerbates Cisplatin-Induced Acute Renal Injury by Xue, Xian, Zhu, Xingwen, Zhou, Lu, Sun, Xiaoli, Gu, Mengru, Liang, Yan, Tan, Mengzhu, Hou, Qing, Wang, Sudan, Dai, Chunsun

“…Introduction: Transcriptional coactivator with PDZ-binding motif (TAZ), a Hippo signaling pathway effector, maintains the balance of cell proliferation,…”
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PP2A Catalytic Subunit α promotes fibroblast activation and kidney fibrosis via ERK pathway by Lu, Qingmiao, Tan, Mengzhu, Hou, Qing, Wang, Mingjie, Dai, Chunsun

“…Protein Phosphatase 2A (PP2A), a main serine/threonine phosphatase, plays a profibrotic role in the development of different organs. However, the role and…”
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