Search Results - "Tan, Liesbet"
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Usage Pattern of Carbamazepine and Associated Severe Cutaneous Adverse Reactions in Singapore Following Implementation of HLA-B15:02 Genotyping as Standard-of-Care
Published in Frontiers in pharmacology (07-05-2020)“…In April 2013, the Ministry of Health and Health Sciences Authority of Singapore jointly issued recommendations for genotyping before starting carbamazepine…”
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Hepatotoxic potential of asarones: in vitro evaluation of hepatotoxicity and quantitative determination in herbal products
Published in Frontiers in pharmacology (20-02-2015)“…α and β asarones are natural constituents of some aromatic plants, especially species of the genus Acorus (Araceae). In addition to reports of beneficial…”
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Are educational materials on medicinal products reaching out and useful to physicians? A survey of Singapore prescribers’ experiences and preferences
Published in Proceedings of Singapore healthcare (01-09-2021)“…Background: Effective benefit–risk communication to healthcare professionals plays a vital role in promoting the rational use of medicinal products. The Health…”
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Tailoring of recommendations to reduce serious cutaneous adverse drug reactions: a pharmacogenomics approach
Published in Pharmacogenomics (01-06-2017)“…The Health Sciences Authority launched a pharmacogenetics initiative in 2008 to facilitate evaluation of pharmacogenetics associations pertinent for Chinese,…”
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Development of Post-Marketing Risk Management Plan Requirements: The Singapore Experience
Published in Pharmaceutical medicine (01-02-2018)“…Historically, global drug safety regulations were generally reactive and post-marketing safety monitoring comprised mainly spontaneous adverse event reporting…”
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Pharmacogenetic Risk for Adverse Reactions to Irinotecan in the Major Ethnic Populations of Singapore: Regulatory Evaluation by the Health Sciences Authority
Published in Drug safety (01-12-2011)“…Background: For genetic polymorphisms known to alter drug effect or safety, regulatory authorities can tap into population genomic databases and other sources…”
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Singapore Pharmacogenomics Portal: a web resource for evaluating human genetic variations of genes responsible for drug responses
Published in Pharmacogenetics and genomics (01-06-2013)“…The Singapore Pharmacogenomics Portal is the first genomics web platform that links public resources from PharmGKB and DrugBank with population genetics data…”
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Introduction to risk management plans in the Singapore context
Published in Singapore medical journal (01-09-2019)“…A risk management plan (RMP) contains an overview of important safety concerns associated with the use of a therapeutic product (TP) and proposed…”
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Lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Singapore: A case series
Published in Annals of the Academy of Medicine, Singapore (01-12-2021)Get more information
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Pharmacogenetic Risk for Adverse Reactions to Irinotecan in the Major Ethnic Populations of Singapore
Published in Drug safety (01-12-2011)“…Background: For genetic polymorphisms known to alter drug effect or safety, regulatory authorities can tap into population genomic databases and other sources…”
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Adverse events associated with the use of complementary medicine and health supplements: An analysis of reports in the Singapore Pharmacovigilance database from 1998 to 2009
Published in Clinical toxicology (Philadelphia, Pa.) (01-07-2012)“…Context. The use of complementary and alternative medicine (CAM), particularly herbal medicine and their derived products, have been increasing. However,…”
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