Search Results - "Tan, K P"

Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent by Li, Lanjuan, Yang, Yi-Yan, Liu, Lihong, Xu, Kaijin, Wang, Huaying, Jeremy Tan, P. K, Fan, Weimin, Venkatraman, Subbu S

“…Antimicrobial cationic peptides are of interest because they can combat multi-drug-resistant microbes. Most peptides form α-helices or β-sheet-like structures…”
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Accelerated antimicrobial discovery via deep generative models and molecular dynamics simulations by Das, Payel, Sercu, Tom, Wadhawan, Kahini, Padhi, Inkit, Gehrmann, Sebastian, Cipcigan, Flaviu, Chenthamarakshan, Vijil, Strobelt, Hendrik, dos Santos, Cicero, Chen, Pin-Yu, Yang, Yi Yan, Tan, Jeremy P. K., Hedrick, James, Crain, Jason, Mojsilovic, Aleksandra

“…The de novo design of antimicrobial therapeutics involves the exploration of a vast chemical repertoire to find compounds with broad-spectrum potency and low…”
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Antimicrobial Polycarbonates: Investigating the Impact of Balancing Charge and Hydrophobicity Using a Same-Centered Polymer Approach by Engler, Amanda C, Tan, Jeremy P. K, Ong, Zhan Yuin, Coady, Daniel J, Ng, Victor W. L, Yang, Yi Yan, Hedrick, James L

“…Biodegradable antimicrobial polymers are a promising solution for combating drug resistant microbes. When designing these materials, the balance between charge…”
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Broad-Spectrum Antimicrobial and Biofilm-Disrupting Hydrogels: Stereocomplex-Driven Supramolecular Assemblies by Li, Yan, Fukushima, Kazuki, Coady, Daniel J., Engler, Amanda C., Liu, Shaoqiong, Huang, Yuan, Cho, John S., Guo, Yi, Miller, Lloyd S., Tan, Jeremy P. K., Ee, Pui Lai Rachel, Fan, Weimin, Yang, Yi Yan, Hedrick, James L.

“…Fighting the resistance: Biodegradable and injectable/moldable hydrogels with hierarchical nanostructures (see picture) were made with broad‐spectrum…”
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Amphiphilic and Hydrophilic Block Copolymers from Aliphatic N‑Substituted 8‑Membered Cyclic Carbonates: A Versatile Macromolecular Platform for Biomedical Applications by Venkataraman, Shrinivas, Tan, Jeremy P. K, Ng, Victor W. L, Tan, Eddy W. P, Hedrick, James L, Yang, Yi Yan

“…Introduction of hydrophilic components, particularly amines and zwitterions, onto a degradable polymer platform, while maintaining precise control over the…”
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Anti‐viral therapy for prevention of perinatal HBV transmission: extending therapy beyond birth does not protect against post‐partum flare by Nguyen, V., Tan, P. K., Greenup, A.‐J., Glass, A., Davison, S., Samarasinghe, D., Holdaway, S., Strasser, S. I., Chatterjee, U., Jackson, K., Locarnini, S. A., Levy, M. T.

“…Summary Background Antepartum anti‐viral therapy (AVT) is often administered to prevent perinatal transmission of hepatitis B virus (HBV) infection. Little is…”
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Evaluation of gene expression measurements from commercial microarray platforms by Tan, Paul K., Downey, Thomas J., Spitznagel Jr, Edward L., Xu, Pin, Fu, Dadin, Dimitrov, Dimiter S., Lempicki, Richard A., Raaka, Bruce M., Cam, Margaret C.

“…Multiple commercial microarrays for measuring genome‐wide gene expression levels are currently available, including oligonucleotide and cDNA, single‐ and…”
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Current Surgical Management of Bilateral Cleft Lip in North America by Tan, Stephan P. K., Greene, Arin K., Mulliken, John B.

“…This study was undertaken to determine contemporary surgical management of bilateral cleft lip. A survey was sent to North American cleft surgeons. Variables…”
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EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms by Venkatesan, N, Wong, J F, Tan, K P, Chung, H H, Yau, Y H, Cukuroglu, E, Allahverdi, A, Nordenskiöld, L, Göke, J, Geifman-Shochat, S, Lin, V C L, Madhusudhan, M S, Su, I-h

“…Recently, we reported that the histone methyltransferase, EZH2, controls leukocyte migration through interaction with the cytoskeleton remodeling effector,…”
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Organocatalytic Approach to Amphiphilic Comb-Block Copolymers Capable of Stereocomplexation and Self-Assembly by Fukushima, Kazuki, Pratt, Russell C, Nederberg, Fredrik, Tan, Jeremy P. K, Yang, Yi Yan, Waymouth, Robert M, Hedrick, James L

“…Biocompatible amphiphilic block copolymers comprised of poly(ethylene glycol) (PEG) as the hydrophilic component and a poly(methylcarboxytrimethylene…”
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Broad-Spectrum Antimicrobial Supramolecular Assemblies with Distinctive Size and Shape by Fukushima, Kazuki, Tan, Jeremy P. K, Korevaar, Peter A, Yang, Yi Yan, Pitera, Jed, Nelson, Alshakim, Maune, Hareem, Coady, Daniel J, Frommer, Jane E, Engler, Amanda C, Huang, Yuan, Xu, Kaijin, Ji, Zhongkang, Qiao, Yuan, Fan, Weimin, Li, Lanjuan, Wiradharma, Nikken, Meijer, E. W, Hedrick, James L

“…With the increased prevalence of antibiotic-resistant infections, there is an urgent need for innovative antimicrobial treatments. One such area being actively…”
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Participation of nuclear factor (erythroid 2‐related), factor 2 in ameliorating lithocholic acid‐induced cholestatic liver injury in mice by Tan, KP, Wood, GA, Yang, M, Ito, S

“…BACKGROUND AND PURPOSE Lithocholic acid (LCA), the most toxic bile acid, induces cholestatic liver injury in rodents. We previously showed that LCA activates…”
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Delivery of Anticancer Drugs Using Polymeric Micelles Stabilized by Hydrogen-Bonding Urea Groups by Tan, Jeremy P. K., Kim, Sung Ho, Nederberg, Fredrik, Fukushima, Kazuki, Coady, Daniel J., Nelson, Alshakim, Yang, Yi Yan, Hedrick, James L.

“…Polymeric micelles comprising a hydrogen‐bonding core were formed from block copolymers with pendant urea groups and explored as drug delivery vehicles. The…”
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Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection by Yawata, N, Selva, K J, Liu, Y-C, Tan, K P, Lee, A W L, Siak, J, Lan, W, Vania, M, Arundhati, A, Tong, L, Li, J, Mehta, J S, Yawata, M

“…The most severe form of virus-induced inflammation at the ocular surface is epidemic keratoconjunctivitis (EKC), often caused by group D human adenoviruses…”
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Assessment of soil bacterial communities on Alexander Island (in the maritime and continental Antarctic transitional zone) by Chong, C. W., Convey, P., Pearce, D. A., Tan, I. K. P.

“…Despite an increasing number of Antarctic soil diversity assessments, understanding of the bacterial community composition in the arid soil environments of the…”
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Control of burst release from nanogels via layer by layer assembly by Tan, Jeremy P.K., Wang, Q., Tam, Kam C.

“…Undesirable burst release phenomenon is commonly encountered in nanostructured delivery systems, and should be addressed. The present study demonstrates a…”
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Broad-Spectrum Antimicrobial Polycarbonate Hydrogels with Fast Degradability by Pascual, Ana, Tan, Jeremy P. K, Yuen, Alex, Chan, Julian M. W, Coady, Daniel J, Mecerreyes, David, Hedrick, James L, Yang, Yi Yan, Sardon, Haritz

“…In this study, a new family of broad-spectrum antimicrobial polycarbonate hydrogels has been successfully synthesized and characterized. Tertiary…”
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Biodegradable nanostructures with selective lysis of microbial membranes by Nederberg, Fredrik, Zhang, Ying, Tan, Jeremy P. K., Xu, Kaijin, Wang, Huaying, Yang, Chuan, Gao, Shujun, Guo, Xin Dong, Fukushima, Kazuki, Li, Lanjuan, Hedrick, James L., Yang, Yi-Yan

“…Macromolecular antimicrobial agents such as cationic polymers and peptides have recently been under an increased level of scrutiny because they can combat…”
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Mixed Micelle Formation through Stereocomplexation between Enantiomeric Poly(lactide) Block Copolymers by Kim, Sung Ho, Tan, Jeremy P. K, Nederberg, Fredrik, Fukushima, Kazuki, Yang, Yi Yan, Waymouth, Robert M, Hedrick, James L

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Optical intensity interferometry through atmospheric turbulence by Tan, P. K., Chan, A. H., Kurtsiefer, C.

“…Conventional ground-based astronomical observations suffer from image distortion due to atmospheric turbulence. This can be minimized by choosing suitable…”
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