Search Results - "Tan, Jieqiong"

Unveiling the role of iPLA2β in neurodegeneration: From molecular mechanisms to advanced therapies by Liu, Jiabin, Tan, Jieqiong, Tang, Beisha, Guo, Jifeng

“…Calcium-independent phospholipase A2β (iPLA2β), a member of the phospholipase A2 (PLA2s) superfamily, is encoded by the PLA2G6 gene. Mutations in the PLA2G6…”
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PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury by Tang, Chengyuan, Han, Hailong, Yan, Mingjuan, Zhu, Shiyao, Liu, Jing, Liu, Zhiwen, He, Liyu, Tan, Jieqiong, Liu, Yu, Liu, Hong, Sun, Lin, Duan, Shaobin, Peng, Youming, Liu, Fuyou, Yin, Xiao-Ming, Zhang, Zhuohua, Dong, Zheng

“…Damaged or dysfunctional mitochondria are toxic to the cell by producing reactive oxygen species and releasing cell death factors. Therefore, timely removal of…”
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Molecular chaperones and Parkinson's disease by Hu, Shenglan, Tan, Jieqiong, Qin, Lixia, Lv, Lingling, Yan, Weiqian, Zhang, Hainan, Tang, BeiSha, Wang, Chunyu

“…Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive death of dopaminergic neurons in the substantia nigra and the formation of…”
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The role of Cdk5 in neurological disorders by Ao, Chuncao, Li, Chenchen, Chen, Jinlun, Tan, Jieqiong, Zeng, Liuwang

“…Neurological disorders are a group of disorders with motor, sensory or cognitive damage, caused by dysfunction of the central or peripheral nervous system…”
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ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion by Wang, Ruoxi, Tan, Jieqiong, Chen, Tingting, Han, Hailong, Tian, Runyi, Tan, Ya, Wu, Yiming, Cui, Jingyi, Chen, Fang, Li, Jie, Lv, Lu, Guan, Xinjie, Shang, Shuai, Lu, Jiahong, Zhang, Zhuohua

“…Mutations in cause Kufor-Rakeb syndrome, an autosomal recessive form of juvenile-onset atypical Parkinson's disease (PD). Recent work tied to autophagy and…”
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Farnesoid X receptor mediates hepatic steatosis induced by PM2.5 by Wang, Mengyao, Tan, Jieqiong, Zhou, Ji, Yi, Bin, Huang, Zhijun

“…Ambient particulate matter (PM) newly has been regarded as a conceivable hazard for public health. A large number of studies have described that PM,…”
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Charge-Dependent Regulation in DNA Adsorption on 2D Clay Minerals by Xie, Hongyi, Wan, Zhengqing, Liu, Song, Zhang, Yi, Tan, Jieqiong, Yang, Huaming

“…DNA purification is essential for the detection of human clinical specimens. A non-destructive, controllable, and low reagent consuming DNA extraction method…”
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Heat Shock Protein B8 (HSPB8) Reduces Oxygen-Glucose Deprivation/Reperfusion Injury via the Induction of Mitophagy by Li, Fazhao, Tan, Jieqiong, Zhou, Fangfang, Hu, Zhiping, Yang, Binbin

“…Background/Aims: We have reported the neuroprotective properties of Heat shock protein B8(HSPB8) against oxygen-glucose deprivation/reoxygenation…”
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Regulation of Intracellular Manganese Homeostasis by Kufor-Rakeb Syndrome-associated ATP13A2 Protein by Tan, Jieqiong, Zhang, Tongmei, Jiang, Li, Chi, Jingwei, Hu, Dongshen, Pan, Qian, Wang, Danling, Zhang, Zhuohua

“…Mutations in the ATP13A2 gene are associated with Kufor-Rakeb syndrome (KRS) and are found also in patients with various other types of parkinsonism. ATP13A2…”
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The Fibrosis and Immunological Features of Hypochlorous Acid Induced Mouse Model of Systemic Sclerosis by Meng, Meng, Tan, Jieqiong, Chen, Weilin, Du, Qian, Xie, Bin, Wang, Nian, Zhu, Honglin, Wang, Kangkai

“…Fibrotic animal models are critical for the pathogenesis investigations and drug explorations in systemic sclerosis (SSc). The bleomycin (BLM)-induced mouse…”
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The Roles of ATP13A2 Gene Mutations Leading to Abnormal Aggregation of α-Synuclein in Parkinson’s Disease by Zhang, Fan, Wu, Zhiwei, Long, Fei, Tan, Jieqiong, Gong, Ni, Li, Xiaorong, Lin, Changwei

“…Parkinson’s disease (PD) is the second most common neurodegenerative disease. PARK9 (also known as ATP13A2) is recognized as one of the key genes that cause…”
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Chemical mitophagy modulators: Drug development strategies and novel regulatory mechanisms by Dong, Yu, Zhuang, Xu-Xu, Wang, Yi-Ting, Tan, Jieqiong, Feng, Du, Li, Min, Zhong, Qing, Song, Zhiyin, Shen, Han-Ming, Fang, Evandro F., Lu, Jia-Hong

“…Maintaining mitochondrial homeostasis is a potential therapeutic strategy for various diseases, including neurodegenerative diseases, cardiovascular diseases,…”
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The relationships of vitamin D, vitamin D receptor gene polymorphisms, and vitamin D supplementation with Parkinson's disease by Lv, Lingling, Tan, Xuling, Peng, Xinke, Bai, Rongrong, Xiao, Qile, Zou, Ting, Tan, Jieqiong, Zhang, Hainan, Wang, Chunyu

“…In recent years, many studies have investigated the correlations between Parkinson's disease (PD) and vitamin D status, but the conclusion remains elusive. The…”
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ATP10B variants in Parkinson’s disease: a large cohort study in Chinese mainland population by Zhao, Yuwen, Pan, Hongxu, Wang, Yige, Zeng, Qian, Fang, Zhenghuan, He, Runcheng, Xu, Kun, Zhou, Xiaoxia, Zhou, Xun, Zhou, Zhou, Li, Yanghong, Deng, Penghui, Xu, Yinghui, Xu, Qian, Sun, Qiying, Li, Bin, Zhao, Guihu, Lei, Lifang, Zhang, Hainan, Wang, Chunyu, Tan, Jieqiong, Yan, Xinxiang, Shen, Lu, Jiang, Hong, Li, Jinchen, Guo, Jifeng, Tang, Beisha, Liu, Zhenhua

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Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy by Yang, Chuanbin, Su, Chengfu, Iyaswamy, Ashok, Krishnamoorthi, Senthil Kumar, Zhu, Zhou, Yang, Sichang, Tong, Benjamin Chunkit, Liu, Jia, Sreenivasmurthy, Sravan G., Guan, Xinjie, Kan, Yuxuan, Wu, Aston Jiaxi, Huang, Alexis Shiying, Tan, Jieqiong, Cheung, Kingho, Song, Juxian, Li, Min

“…Alzheimer's disease (AD), characterized by the accumulation of protein aggregates including phosphorylated Tau aggregates, is the most common neurodegenerative…”
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Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer's Disease by Guan, Xinjie, Iyaswamy, Ashok, Sreenivasmurthy, Sravan Gopalkrishnashetty, Su, Chengfu, Zhu, Zhou, Liu, Jia, Kan, Yuxuan, Cheung, King-Ho, Lu, Jiahong, Tan, Jieqiong, Li, Min

“…Eukaryotic cells possess a plethora of regulatory mechanisms to maintain homeostasis and ensure proper biochemical functionality. Autophagy, a central,…”
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Effects of Commonly Used Pesticides in China on the Mitochondria and Ubiquitin-Proteasome System in Parkinson's Disease by Chen, Tingting, Tan, Jieqiong, Wan, Zhengqing, Zou, Yongyi, Afewerky, Henok Kessete, Zhang, Zhuohua, Zhang, Tongmei

“…Evidence continues to accumulate that pesticides are the leading candidates of environmental toxins that may contribute to the pathogenesis of Parkinson's…”
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Olfactory Dysfunction Predicts Disease Progression in Parkinson's Disease: A Longitudinal Study by He, Runcheng, Zhao, Yuwen, He, Yan, Zhou, Yangjie, Yang, Jinxia, Zhou, Xiaoting, Zhu, Liping, Zhou, Xun, Liu, Zhenhua, Xu, Qian, Sun, Qiying, Tan, Jieqiong, Yan, Xinxiang, Tang, Beisha, Guo, Jifeng

“…Olfactory dysfunction (hyposmia) is an important non-motor symptom of Parkinson's disease (PD). To investigate the potential prognostic value of hyposmia as a…”
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NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP by Lv, Liang, Mo, Jinyou, Qing, Yumin, Wang, Shuchao, Chen, Leijie, Mei, Anna, Xu, Ru, Huang, Hualin, Tan, Jieqiong, Li, Yifu, Liu, Jia

“…The ribosome-associated protein quality control (RQC) pathway acts as a translational surveillance mechanism to maintain proteostasis. In mammalian cells, the…”
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The association between LIN28A gene rare variants and Parkinson’s disease in Chinese population by Huang, Xiurong, Zhao, Yuwen, Pan, Hongxu, Wang, Yige, Liu, Zhenhua, Xu, Qian, Sun, Qiying, Tan, Jieqiong, Yan, Xinxiang, Li, Jinchen, Tang, Beisha, Guo, Jifeng

“…•The susceptibility gene of Parkinson’s disease: focus on LIN28A gene.•The burden analysis of rare variants in LIN28A gene between PD patients and healthy…”
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