Search Results - "Tan, Jianglin"
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Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases
Published in Nature communications (03-06-2020)“…Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment is currently available clinically. The development of…”
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Nano-silver-decorated microfibrous eggshell membrane: processing, cytotoxicity assessment and optimization, antibacterial activity and wound healing
Published in Scientific reports (27-03-2017)“…An ideal wound dressing can both promote wound healing and prevent bacterial infection. Here, we report a potential dressing prepared by incorporating an…”
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Current progress in understanding the molecular pathogenesis of burn scar contracture
Published in Burns and trauma (01-12-2017)“…Abnormal wound healing is likely to induce scar formation, leading to dysfunction, deformity, and psychological trauma in burn patients. Despite the…”
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A multifunctional platform with single-NIR-laser-triggered photothermal and NO release for synergistic therapy against multidrug-resistant Gram-negative bacteria and their biofilms
Published in Journal of nanobiotechnology (15-04-2020)“…Infectious diseases caused by multidrug-resistant (MDR) bacteria, especially MDR Gram-negative strains, have become a global public health challenge…”
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Nitric oxide enhances keratinocyte cell migration by regulating Rho GTPase via cGMP-PKG signalling
Published in PloS one (23-03-2015)“…Nitric oxide (NO) has been shown to improve wound healing, but the mechanism underlying this function is not well defined. Here, we explored the effect of NO…”
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Glycosaminoglycans’ Ability to Promote Wound Healing: From Native Living Macromolecules to Artificial Biomaterials
Published in Advanced science (01-03-2024)“…Glycosaminoglycans (GAGs) are important for the occurrence of signaling molecules and maintenance of microenvironment within the extracellular matrix (ECM) in…”
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A ROS-responsive, self-immolative and self-reporting hydrogen sulfide donor with multiple biological activities for the treatment of myocardial infarction
Published in Bioactive materials (01-03-2022)“…Myocardial infarction (MI), as one of the leading causes of global death, urgently needs effective therapies. Recently, hydrogen sulfide (H2S) has been…”
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In-Situ-Generated Vasoactive Intestinal Peptide Loaded Microspheres in Mussel-Inspired Polycaprolactone Nanosheets Creating Spatiotemporal Releasing Microenvironment to Promote Wound Healing and Angiogenesis
Published in ACS applied materials & interfaces (23-03-2016)“…Vasoactive intestinal peptide (VIP) was reported to promote angiogenesis. Electrospun nanofibers lead to idea wound dressing substrates. Here we report a…”
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P311 promotes renal fibrosis via TGFβ1/Smad signaling
Published in Scientific reports (30-11-2015)“…P311, a gene that was identified in 1993, has been found to have diverse biological functions in processes such as cell proliferation, migration and…”
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Treatment of hypertrophic scars with ablative fractional carbon dioxide laser assisted with different topical triamcinolone delivery ways
Published in Heliyon (01-12-2023)“…Ablative fractional carbon dioxide laser has been used with triamcinolone to treat hypertrophic scars, resulting in promising success rates. However, there are…”
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A novel fluorescent probe for real-time imaging of thionitrous acid under inflammatory and oxidative conditions
Published in Redox biology (01-08-2022)“…Thionitrous acid (HSNO), a crosstalk intermediate of two crucial gasotransmitters nitric oxide and hydrogen sulfide, plays a critical role in redox regulation…”
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Wound management and outcome of 595 electrical burns in a major burn center
Published in The Journal of surgical research (15-06-2017)“…Abstract Background Electrical burns are important causes of trauma worldwide. This study aims to analyze the clinical characteristics, wound management, and…”
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CD86 is an activation receptor for NK cell cytotoxicity against tumor cells
Published in PloS one (11-12-2013)“…CTLA4Ig has been successfully used in the clinic for suppression of T cell activation. However, patients treated with CTLA4Ig experienced reduced incidence of…”
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Investigating the role of P311 in the hypertrophic scar
Published in PloS one (09-04-2010)“…The mechanisms of hypertrophic scar formation are not fully understood. We previously screened the differentially expressed genes of human hypertrophic scar…”
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Three-Dimensional Histological Structures of the Human Dermis
Published in Tissue engineering. Part C, Methods (01-09-2015)“…Spatial information has been shown to be critical for cell differentiation and function. Therefore, a better understanding of skin microstructures is very…”
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Correction to: A multifunctional platform with single-NIR-laser-triggered photothermal and NO release for synergistic therapy against multidrug-resistant Gram-negative bacteria and their biofilms
Published in Journal of nanobiotechnology (25-09-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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Joint contractures in severe burn patients with early rehabilitation intervention in one of the largest burn intensive care unit in China: a descriptive analysis
Published in Burns and trauma (2019)“…Joint contracture is the major clinical complication in burn patients, especially, the severe burn patients. This study aimed to investigate the number and…”
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iTRAQ-based proteomic profiling reveals different protein expression between normal skin and hypertrophic scar tissue
Published in Burns and trauma (2015)“…A hypertrophic scar is a unique fibrotic disease that only exists in humans. Despite advances in burn care and rehabilitation, as well as progress in the…”
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Embryonic porcine skin precursors can successfully develop into integrated skin without teratoma formation posttransplantation in nude mouse model
Published in PloS one (18-01-2010)“…How to improve the wound healing quality of severe burn patients is still a challenge due to lack of skin appendages and rete ridges, no matter how much…”
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