Search Results - "Tan, J. C"

MOF-Based Polymeric Nanocomposite Films as Potential Materials for Drug Delivery Devices in Ocular Therapeutics by Gandara-Loe, J, Souza, B. E, Missyul, A, Giraldo, G, Tan, J.-C, Silvestre-Albero, J

“…Novel MOF-based polymer nanocomposite films were successfully prepared using Zr-based UiO-67 as a metal–organic framework (MOF) and polyurethane (PU) as a…”
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Systematic review and meta-analysis of randomized clinical trials of self-expanding metallic stents as a bridge to surgery versus emergency surgery for malignant left-sided large bowel obstruction by Tan, C. J., Dasari, B. V. M., Gardiner, K.

“…Background: Use of self‐expanding metallic stents (SEMS) as a bridge to surgery has been suggested as an alternative management for acute malignant left‐sided…”
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MAGNETIC FIELDS IN HIGH-MASS INFRARED DARK CLOUDS by Pillai, T, Kauffmann, J, Tan, J C, Goldsmith, P F, Carey, S J, Menten, K M

“…High-mass stars are cosmic engines known to dominate the energetics in the Milky Way and other galaxies. However, their formation is still not well understood…”
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Translation factor eIF5a is essential for IFNγ production and cell cycle regulation in primary CD8+ T lymphocytes by Tan, Thomas C. J., Kelly, Van, Zou, Xiaoyan, Wright, David, Ly, Tony, Zamoyska, Rose

“…Control of mRNA translation adjusts protein production rapidly and facilitates local cellular responses to environmental conditions. Traditionally initiation…”
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The Hi-GAL compact source catalogue – II. The 360° catalogue of clump physical properties by Elia, Davide, Merello, M, Molinari, S, Schisano, E, Zavagno, A, Russeil, D, Mège, P, Martin, P G, Olmi, L, Pestalozzi, M, Plume, R, Ragan, S E, Benedettini, M, Eden, D J, Moore, T J T, Noriega-Crespo, A, Paladini, R, Palmeirim, P, Pezzuto, S, Pilbratt, G L, Rygl, K L J, Schilke, P, Strafella, F, Tan, J C, Traficante, A, Baldeschi, A, Bally, J, Giorgio, A M di, Fiorellino, E, Liu, S J, Piazzo, L, Polychroni, D

“…ABSTRACT We present the 360° catalogue of physical properties of Hi-GAL compact sources, detected between 70 and 500 $\mu$m. This release not only completes…”
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The dynamical properties of dense filaments in the infrared dark cloud G035.39−00.33 by Henshaw, J. D., Caselli, P., Fontani, F., Jiménez-Serra, I., Tan, J. C.

“…Infrared dark clouds (IRDCs) are unique laboratories to study the initial conditions of high-mass star and star cluster formation. We present high-sensitivity…”
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Investigating the structure and fragmentation of a highly filamentary IRDC by Henshaw, J. D., Caselli, P., Fontani, F., Jiménez-Serra, I., Tan, J. C., Longmore, S. N., Pineda, J. E., Parker, R. J., Barnes, A. T.

“…We present 3.7 arcsec (∼0.05 pc) resolution 3.2 mm dust continuum observations from the Institut de Radioastronomie Millimétrique Plateau de Bure…”
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High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike by Tan, Timothy J. C., Mou, Zongjun, Lei, Ruipeng, Ouyang, Wenhao O., Yuan, Meng, Song, Ge, Andrabi, Raiees, Wilson, Ian A., Kieffer, Collin, Dai, Xinghong, Matreyek, Kenneth A., Wu, Nicholas C.

“…Designing prefusion-stabilized SARS-CoV-2 spike is critical for the effectiveness of COVID-19 vaccines. All COVID-19 vaccines in the US encode spike with…”
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Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution by Liang, Weiwen, Tan, Timothy J. C, Wang, Yiquan, Lv, Huibin, Sun, Yuanxin, Bruzzone, Roberto, Mok, Chris K. P, Wu, Nicholas C

“…Egg-adaptive mutations in influenza hemagglutinin (HA) often emerge during the production of egg-based seasonal influenza vaccines, which contribute to the…”
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SiO emission as a probe of cloud–cloud collisions in infrared dark clouds by Cosentino, G, Jiménez-Serra, I, Henshaw, J D, Caselli, P, Viti, S, Barnes, A T, Tan, J C, Fontani, F, Wu, B

“…ABSTRACT Infrared dark clouds (IRDCs) are very dense and highly extincted regions that host the initial conditions of star and stellar cluster formation. It is…”
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ALMA–IRDC: dense gas mass distribution from cloud to core scales by Barnes, A T, Henshaw, J D, Fontani, F, Pineda, J E, Cosentino, G, Tan, J C, Caselli, P, Jiménez-Serra, I, Law, C Y, Avison, A, Bigiel, F, Feng, S, Kong, S, Longmore, S N, Moser, L, Parker, R J, Sánchez-Monge, Á, Wang, K

“…ABSTRACT Infrared dark clouds (IRDCs) are potential hosts of the elusive early phases of high mass star formation (HMSF). Here, we conduct an in-depth analysis…”
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Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning by Lei, Ruipeng, Qing, Enya, Odle, Abby, Yuan, Meng, Gunawardene, Chaminda D., Tan, Timothy J. C., So, Natalie, Ouyang, Wenhao O., Wilson, Ian A., Gallagher, Tom, Perlman, Stanley, Wu, Nicholas C., Wong, Lok-Yin Roy

“…The fusion peptide of SARS-CoV-2 spike protein is functionally important for membrane fusion during virus entry and is part of a broadly neutralizing epitope…”
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Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual worms by Tan, Thomas C. J, Rahman, Ruman, Jaber-Hijazi, Farah, Felix, Daniel A, Chen, Chen, Louis, Edward J, Aboobaker, Aziz

“…In most sexually reproducing animals, replication and maintenance of telomeres occurs in the germ line and during early development in embryogenesis through…”
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Parsec-scale SiO emission in an infrared dark cloud by Jiménez-Serra, I., Caselli, P., Tan, J. C., Hernandez, A. K., Fontani, F., Butler, M. J., van Loo, S.

“…We present high-sensitivity 2 × 4 arcmin2 maps of the J= 2→1 rotational lines of SiO, CO, 13CO and C18O, observed towards the filamentary infrared dark cloud…”
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Similar complex kinematics within two massive, filamentary infrared dark clouds by Barnes, A T, Henshaw, J D, Caselli, P, Jiménez-Serra, I, Tan, J C, Fontani, F, Pon, A, Ragan, S

“…Abstract Infrared dark clouds (IRDCs) are thought to be potential hosts of the elusive early phases of high-mass star formation. Here, we conduct an in-depth…”
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Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin by Lei, Ruipeng, Liang, Weiwen, Ouyang, Wenhao O., Hernandez Garcia, Andrea, Kikuchi, Chika, Wang, Shengyang, McBride, Ryan, Tan, Timothy J. C., Sun, Yuanxin, Chen, Chunke, Graham, Claire S., Rodriguez, Lucia A., Shen, Ivana R., Choi, Danbi, Bruzzone, Roberto, Paulson, James C., Nair, Satish K., Mok, Chris K. P., Wu, Nicholas C.

“…The receptor-binding site of influenza A virus hemagglutinin partially overlaps with major antigenic sites and constantly evolves. In this study, we observe…”
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Prevalence and mechanisms of evolutionary contingency in human influenza H3N2 neuraminidase by Lei, Ruipeng, Tan, Timothy J. C., Hernandez Garcia, Andrea, Wang, Yiquan, Diefenbacher, Meghan, Teo, Chuyun, Gopan, Gopika, Tavakoli Dargani, Zahra, Teo, Qi Wen, Graham, Claire S., Brooke, Christopher B., Nair, Satish K., Wu, Nicholas C.

“…Neuraminidase (NA) of human influenza H3N2 virus has evolved rapidly and been accumulating mutations for more than half-century. However, biophysical…”
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Gas kinematics and excitation in the filamentary IRDC G035.39-00.33 by Jiménez-Serra, I., Caselli, P., Fontani, F., Tan, J. C., Henshaw, J. D., Kainulainen, J., Hernandez, A. K.

“…Some theories of dense molecular cloud formation involve dynamical environments driven by converging atomic flows or collisions between preexisting molecular…”
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Characterization of microRNA expression profiles in Leishmania‐infected human phagocytes by Geraci, N. S., Tan, J. C., McDowell, M. A.

“…Summary Leishmania are intracellular protozoa that influence host immune responses eliciting parasite species‐specific pathologies. MicroRNAs (miRNAs) are…”
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Measuring the ionisation fraction in a jet from a massive protostar by Fedriani, R., Caratti o Garatti, A., Purser, S. J. D., Sanna, A., Tan, J. C., Garcia-Lopez, R., Ray, T. P., Coffey, D., Stecklum, B., Hoare, M.

“…It is important to determine if massive stars form via disc accretion, like their low-mass counterparts. Theory and observation indicate that protostellar jets…”
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