Search Results - "Tan, Guishan"

Neolignans from Selaginella trichoclada by Peng, Yang, Guishan, Tan, Yang, Xie

“…A new neolignan, (–)-(7 R ,8 S ,7′ R ,8′ S ,8′′ S )-4′-hydroxy-3′,3′′,5′′-trimethoxy-4′′-O- β…”
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Preparation of new halogenated diphenyl pyrazine analogs in Escherichia coli by a mono-module fungal nonribosomal peptide synthetase from Penicillium herquei by Yang, Can, Xu, Yuanyuan, Xu, Kangping, Tan, Guishan, Yu, Xia

“…[Display omitted] •The biocatalytic approaches to obtain diphenyl pyrazine analogs.•Exploration of the catalytic ability of HqlA towards tyrosine…”
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Anticancer potential of Hericium erinaceus extracts against human gastrointestinal cancers by Li, Guang, Yu, Kai, Li, Fushuang, Xu, Kangping, Li, Jing, He, Shujin, Cao, Shousong, Tan, Guishan

“…Hericium is a genus of mushrooms (fungus) in the Hericiaceae family. Hericium erinaceus (HE) has been used for the treatment of digestive diseases for over…”
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Biflavonoids from Selaginella doederleinii as Potential Antitumor Agents for Intervention of Non-Small Cell Lung Cancer by Kang, Fenghua, Zhang, Sha, Chen, Dekun, Tan, Jianbing, Kuang, Min, Zhang, Jinlin, Zeng, Guangyuan, Xu, Kangping, Zou, Zhenxing, Tan, Guishan

“…Four new biflavonoids ( - ) were isolated from together with a known biflavonoid derivative ( ). Their structures contained a rare linker of individual…”
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Synthesis of Halogenated Diphenylpiperazines from L-Tyrosine Derivatives by Biotransformation by Bao, Shumin, Zhong, Xiaoyan, Wan, Ying, Tan, Guishan, Xu, Kangping, Yu, Xia

“…Piperazine-containing compounds tend to exhibit good biological activities. In this study, four novel halogenated diphenylpiperazines were biosynthesized in…”
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Inhibitors of 11β-Hydroxylase (CYP11B1) for Treating Diseases Related to Excess Cortisol by Zhu, Weixing, Chen, Zhuo, Li, Qianbin, Tan, Guishan, Hu, Gaoyun

“…The overproduction of cortisol is associated with many severe and life-threatening diseases, such as Cushing's syndrome (CS) and chronic wound healing…”
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A New Stilbenoid from Caryopteris incana by Chen, Dekun, Zhang, Kai, Tan, Jianbing, Zhang, Sha, Xu, Kangping, Wang, Wenxuan, Kang, Fenghua, Zou, Zhenxing, Tan, Guishan

“…A new stilbenoid, methyl 2,4-dihydroxy-6-(4-hydroxyphenethyl)-3-methylbenzoate ( 1 ), along with 11 known compounds, cirsimaritin ( 2 ), cirsiliol ( 3 ),…”
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The research of traffic density extraction method under vehicular ad hoc network environment by Wu, Zhizhou, Zhang, Yiming, Tan, Guishan, Hu, Jia

“…Purpose Traffic density is one of the most important parameters to consider in the traffic operation field. Owing to limited data sources, traditional methods…”
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Elucidation of a Dearomatization Route in the Biosynthesis of Oxysporidinone Involving a TenA‐like Cytochrome P450 Enzyme by Li, Dan, Wang, Wenxuan, Xu, Kangping, Li, Jing, Long, Bi, Li, Zhansheng, Tan, Guishan, Yu, Xia

“…Oxidative dearomatization of phenols is an important transformation for synthesis of complex molecules. Oxysporidinone and related 2‐pyridones feature a…”
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Challenging Aromaticity: Revealing a Thioesterase Domain in a Fungal Nonreducing Polyketide Synthase Governing the Production of 3‑Methylene Isochromanone by Bai, Guitao, Li, Dan, Wang, Yi, Yi, Jiale, Xu, Kangping, Wang, Wenxuan, Li, Jing, Tan, Guishan, Yu, Xia

“…Thioesterase (TE) domain exerts a great influence over the structure of the final product and TE-released nonreduced polyketides (nrPKs) retain aromaticity…”
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Design, synthesis and evaluation of nitric oxide releasing derivatives of 2,4-diaminopyrimidine as novel FAK inhibitors for intervention of metastatic triple-negative breast cancer by Zhang, Jinlin, Xu, Kangping, Yang, Fei, Qiu, Yaoren, Li, Jiayi, Li, Jing, Wang, Wenxuan, Tan, Guishan, Zou, Zhenxing, Kang, Fenghua

“…To search for novel medicines for intervention of triple-negative breast cancer (TNBC), a series of phenylsulfonyl furoxan-based 2,4-diaminopyrimidine…”
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Discovery of novel chloropyramine-cinnamic acid hybrids as potential FAK inhibitors for intervention of metastatic triple-negative breast cancer by Yang, Fei, Xu, Kangping, Zhang, Sha, Zhang, Jinlin, Qiu, Yaoren, Luo, Jin, Tan, Guishan, Zou, Zhenxing, Wang, Wenxuan, Kang, Fenghua

“…[Display omitted] •7d exhibited low micromolar antiproliferative activity against TNBC cells but sparing non-tumor breast cells.•7d significantly inhibited…”
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A Single Amino Acid Switch Alters the Prenyl Donor Specificity of a Fungal Aromatic Prenyltransferase toward Biflavonoids by Xu, Yuanyuan, Li, Dan, Tan, Guishan, Zhang, Yan, Li, Zhansheng, Xu, Kangping, Li, Shu-Ming, Yu, Xia

“…Biflavonoids are pharmaceutically important compounds. Prenylation usually improves bioactivity; however, prenylated biflavonoids are rare in nature. Here, we…”
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A two-way bandwidth maximization model for green-wave optimization control of transit priority by Wang, Yizhe, Wu, Zhizhou, Liu, Yangdong, Yang, Xiaoguang, Guishan Tan

“…Arterial coordinated control has practical significance for transit priority control when intersection spacing is relatively short and similar. In this paper…”
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Selagintriflavonoids with BACE1 inhibitory activity from the fern Selaginella doederleinii by Zou, Zhenxing, Xu, Pingsheng, Zhang, Guogang, Cheng, Fei, Chen, Kai, Li, Jing, Zhu, Weixing, Cao, Dongsheng, Xu, Kangping, Tan, Guishan

“…Eight triflavonoids, selagintriflavonoids A-H, were isolated from whole herbs of Selaginella doederleinii. The structures of compounds selagintriflavonoids A-C…”
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Dearomative gem -diprenylation of hydroxynaphthalenes by an engineered fungal prenyltransferase by Xu, Yuanyuan, Li, Dan, Wang, Wenxuan, Xu, Kangping, Tan, Guishan, Li, Jing, Li, Shu-Ming, Yu, Xia

“…Prenylation usually improves structural diversity and bioactivity in natural products. Unlike the discovered enzymatic gem -diprenylation of mono- and…”
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A novel Apigenin derivative suppresses renal cell carcinoma via directly inhibiting wild-type and mutant MET by Li, Jing, Tan, Guishan, Cai, Yabo, Liu, Ruihuan, Xiong, Xiaolin, Gu, Baohua, He, Wei, Liu, Bing, Ren, Qingyun, Wu, Jianping, Chi, Bo, Zhang, Hang, Zhao, Yanzhong, Xu, Yangrui, Zou, Zhenxing, Kang, Fenghua, Xu, Kangping

“…[Display omitted] MET, the receptor of hepatocyte growth factor (HGF), is a driving factor in renal cell carcinoma (RCC) and also a proven drug target for…”
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Selective geranylation of biflavonoids by Aspergillus terreus aromatic prenyltransferase (AtaPT) by Xu, Kangping, Yang, Can, Xu, Yuanyuan, Li, Dan, Bao, Shumin, Zou, Zhenxing, Kang, Fenghua, Tan, Guishan, Li, Shu-Ming, Yu, Xia

“…Prenylation increases the bioactivity of flavonoids. Herein, we report the first examples of regioselective enzymatic geranylation of biflavonoids using…”
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Regiospecific 7-O-prenylation of anthocyanins by a fungal prenyltransferase by Bao, Shumin, Luo, Ling, Wan, Ying, Xu, Kangping, Tan, Guishan, Fan, Jie, Li, Shu-Ming, Yu, Xia

“…[Display omitted] •Prenylation often leads to enhanced bioactivity on flavonoids.•We demonstrate the first example for prenylation of anthocyanins.•CdpC3PT…”
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Silica-gel-supported Ce(SO4)2·4H2O-mediated cyclization of 2′-amino and 2′-hydroxychalcones under solvent-free conditions by Liu, Ruihuan, Zhang, Yan, Xu, Kangping, Tan, Guishan

“…A simple, efficient, and environmentally friendly approach for the synthesis of flavones, aza-flavones, and aza-flavanones from corresponding 2′-hydroxy or…”
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