Search Results - "Tan, Eddy"
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1
Amphiphilic and Hydrophilic Block Copolymers from Aliphatic N‑Substituted 8‑Membered Cyclic Carbonates: A Versatile Macromolecular Platform for Biomedical Applications
Published in Biomacromolecules (09-01-2017)“…Introduction of hydrophilic components, particularly amines and zwitterions, onto a degradable polymer platform, while maintaining precise control over the…”
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Overcoming Barriers in Polycarbonate Synthesis: A Streamlined Approach for the Synthesis of Cyclic Carbonate Monomers
Published in Macromolecules (23-02-2021)“…Accessing cyclic carbonate monomers on a large scale is critical for the development of any new carbonate-based materials platform. The synthesis of carbonate…”
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3
Advances in sample preparation and analytical techniques for lipidomics study of clinical samples
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-03-2015)“…•Lipids are important biological molecules for the maintenance of a healthy body.•Clinical lipidomics helps to understand lipid-related human…”
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4
Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926)
Published in Journal of medicinal chemistry (23-07-2009)“…Recent evidence suggests that blocking aberrant hedgehog pathway signaling may be a promising therapeutic strategy for the treatment of several types of…”
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5
Broad Spectrum Macromolecular Antimicrobials with Biofilm Disruption Capability and In Vivo Efficacy
Published in Advanced healthcare materials (01-08-2017)“…In this study, antimicrobial polymers are synthesized by the organocatalytic ring‐opening polymerization of an eight‐membered heterocyclic carbonate monomer…”
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6
Nanocomplexes of Biodegradable Anticancer Macromolecules: Prolonged Plasma Half‐Life, Reduced Toxicity, and Increased Tumor Targeting
Published in Advanced healthcare materials (01-07-2023)“…Anticancer drug resistance is a large contributing factor to the global mortality rate of cancer patients. Anticancer macromolecules such as polymers have been…”
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7
Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range
Published in Journal of Chromatography A (06-12-2013)“…•We present a method for the determination of high pI antibody charge variants.•It is based on IEX chromatography in association with highly linear pH…”
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8
Human Transport Protein Carrier for Controlled Photoactivation of Antitumor Prodrug and Real-Time Intracellular Tumor Imaging
Published in Bioconjugate chemistry (20-05-2015)“…Current anticancer chemotherapy often suffers from poor tumor selectivity and serious drug resistance. Proper vectors for targeted delivery and controlled drug…”
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9
Amphiphilic Sulfonated Polycarbonates Inactivate SARS-CoV‑2 in Seconds
Published in Macromolecules (08-08-2023)“…The global pandemic due to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to more than 661 million infections and over 6.6 million…”
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10
Lipidomic Profiling of Lung Pleural Effusion Identifies Unique Metabotype for EGFR Mutants in Non-Small Cell Lung Cancer
Published in Scientific reports (14-10-2016)“…Cytology and histology forms the cornerstone for the diagnosis of non-small cell lung cancer (NSCLC) but obtaining sufficient tumour cells or tissue biopsies…”
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11
Comparison of reproductive indicators and analysis of the reproductive seasonality of the tinfoil barb, Puntius schwanenfeldii, in the Perak River, Malaysia
Published in Environmental biology of fishes (01-08-1999)“…The reproductive seasonality of Puntius schwanenfeldii from the Perak River, Malaysia was investigated over a 19 month period. Females greater than 160g had…”
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12
Liquid Formulations for Stabilizing IgMs During Physical Stress and Long-Term Storage
Published in Pharmaceutical research (01-03-2013)“…ABSTRACT Purpose To develop a liquid formulation for IgMs to survive physical stress and storage. Methods Stabilizing formulations for 8 monoclonal…”
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13
Su1483 Novel Metabolomics Markers for Characterization and Early Detection of Malignancy in Pancreatic Cysts
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2015)Get full text
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14
Change of steroidogenic pathways in the ovary of a tropical catfish, Clarias macrocephalus, Gunther, after hCG treatment
Published in General and comparative endocrinology (01-11-1989)“…Adult female catfish received an im injection of 454 IU hCG in 0.2 ml saline. Sixteen hours later, the ovarian tissue from the hCG-treated or control fish was…”
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15
TBSAM: an access method for efficient processing of statistical queries
Published in IEEE transactions on knowledge and data engineering (01-12-1989)“…The domain of statistical and scientific databases is targeted here, and the class of aggregate queries which are very often encountered in this domain is…”
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On efficient matching and optimization of rule sets in AI and databases
Published 01-01-1990“…Expert systems with large knowledge bases have necessitated the use of database technology for efficient knowledge management. Emerging applications like…”
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Dissertation