Search Results - "Tan, Darlene Q."

Ammonia synthons for the multicomponent assembly of complex γ-lactams by Tan, Darlene Q., Martin, Kevin S., Fettinger, James C., Shaw, Jared T., Schreiber, Stuart L.

“…The synthesis of γ-lactams that are unsubstituted at the 1-position (nitrogen) as well as their subsequent N-functionalization is reported. A recently…”
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Mechanistic Investigation of Castagnoli–Cushman Multicomponent Reactions Leading to a Three-Component Synthesis of Dihydroisoquinolones by Howard, Sara Y, Di Maso, Michael J, Shimabukuro, Kristin, Burlow, Noah P, Tan, Darlene Q, Fettinger, James C, Malig, Thomas C, Hein, Jason E, Shaw, Jared T

“…The mechanisms for the three- and four-component variants of the Castagnoli–Cushman reaction (CCR) have been investigated. A series of crossover experiments…”
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Stereocontrol in Asymmetric γ‑Lactam Syntheses from Imines and Cyanosuccinic Anhydrides by Pattawong, Ommidala, Tan, Darlene Q, Fettinger, James C, Shaw, Jared T, Cheong, Paul Ha-Yeon

“…Computations (SCS-MP2//B3LYP) reveal that the asymmetric synthesis of highly substituted γ-lactams with three stereogenic centers, including one quaternary…”
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Stereoselective Synthesis of γ‑Lactams from Imines and Cyanosuccinic Anhydrides by Tan, Darlene Q, Younai, Ashkaan, Pattawong, Ommidala, Fettinger, James C, Cheong, Paul Ha-Yeon, Shaw, Jared T

“…A reaction between imines and anhydrides has been developed with chiral disubstituted anhydrides and chiral imines. The synthesis of highly substituted…”
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Diastereoselective Synthesis of and Mechanistic Understanding for the Formation of 2-Piperidinones from Imines and Cyano-Substituted Anhydrides by Di Maso, Michael J., Snyder, Kevin M., De Souza Fernandes, Fábio, Pattawong, Ommidala, Tan, Darlene Q., Fettinger, James C., Cheong, Paul Ha-Yeon, Shaw, Jared T.

“…2‐Piperidinones are synthesized in a single step from imines and 2‐cyano glutaric anhydrides. The reaction provides the products in good diastereoselectivity…”
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Synthesis of a γ-Lactam Library via Formal Cycloaddition of Imines and Substituted Succinic Anhydrides by Tan, Darlene Q, Atherton, Amy L, Smith, Austin J, Soldi, Cristian, Hurley, Katherine A, Fettinger, James C, Shaw, Jared T

“…Formal cycloaddition reactions between imines and cyclic anhydrides serve as starting point for the synthesis of diverse libraries of small molecules. The…”
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Ammonia synthons for the multicomponent assembly of complex [gamma]-lactams by Tan, Darlene Q, Martin, Kevin S, Fettinger, James C, Shaw, Jared T

“…The synthesis of ...-lactams that are unsubstituted at the 1-position (nitrogen) as well as their subsequent N-functionalization is reported. A recently…”
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Ammonia synthons for the multicomponent assembly of complex γ-lactams by Tan, Darlene Q, Martin, Kevin S, Fettinger, James C, Shaw, Jared T

“…The synthesis of γ-lactams that are unsubstituted at the 1-position (nitrogen) as well as their subsequent N-functionalization is reported. A recently…”
Get full text